Syndrome differentiation and treatment of hypertrophic cardiomyopathy based on theory of endowment and stasis-toxin

PANG Qinghua; CHEH Yifan; OUYANG Jiahui; A Runa; LIU Yanjiao; JIANG Zhonghui; GAO Zhuye

doi:10.16025/j.1674-1307.2025.10.005

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Syndrome differentiation and treatment of hypertrophic cardiomyopathy based on theory of endowment and stasis-toxin

更新时间：2025-12-15

- Syndrome differentiation and treatment of hypertrophic cardiomyopathy based on theory of endowment and stasis-toxin
- Beijing Journal of Traditional Chinese Medicine Vol. 44, Issue 10, Pages: 1250-1254(2025)
- 作者机构：
  
  1.北京中医药大学研究生院，北京 100029
  2.中国中医科学院西苑医院，北京 100091
  3.中国中医科学院眼科医院，北京 100040
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2025.10.005
  CLC：
- Received：01 December 2024，
  
  Published：25 October 2025
- 稿件说明：
移动端阅览
庞清华，陈一帆，欧阳嘉慧，等.基于“禀赋”和“瘀毒”探讨肥厚型心肌病的辨治［J］.北京中医药，2025，44（10）：1250-1254.

PANG Qinghua,CHEH Yifan,OUYANG Jiahui,et al.Syndrome differentiation and treatment of hypertrophic cardiomyopathy based on theory of endowment and stasis-toxin[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1250-1254.
庞清华，陈一帆，欧阳嘉慧，等.基于“禀赋”和“瘀毒”探讨肥厚型心肌病的辨治［J］.北京中医药，2025，44（10）：1250-1254. DOI： 10.16025/j.1674-1307.2025.10.005.

PANG Qinghua,CHEH Yifan,OUYANG Jiahui,et al.Syndrome differentiation and treatment of hypertrophic cardiomyopathy based on theory of endowment and stasis-toxin[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1250-1254. DOI： 10.16025/j.1674-1307.2025.10.005.

摘要

中医学认为，肥厚型心肌病的病因病机可以从“禀赋”和“瘀毒”两方面进行阐释。本文将肥厚型心肌病的病程分为3个阶段：早期，禀赋不良、多虚多瘀、瘀毒潜伏为发病基础；进展期，瘀毒互结、瘀阻脉络、毒损心体为关键病机；后期，瘀毒搏结、血塞气闭、阳脱阴竭造成危重后果。辨治思路为：早期辨识禀赋、调理体质以实现预防；进展期以活血化瘀、扶正解毒为主，随证加减；后期宣通解毒、顾护真元以应对危重变证。

Abstract

In traditional Chinese medicine （TCM）， the etiology and pathogenesis of hypertrophic cardiomyopath

y can be explained from the perspectives of endowment and stasis-toxin. This article divides the disease course into three stages. In the early stage， poor endowment， a tendency toward deficiency and stasis， and latent stasis and toxin form the basis of pathogenesis. In the progressive stage， the key pathological mechanisms include the entanglement of stasis and toxin， obstruction of the collaterals by stasis， and toxin-induced damage to the heart. In the late stage， the combination of stasis and toxin， blockage of blood and

， and exhaustion of

yang

and

yin

result in critical consequences. The diagnostic and therapeutic approach is as follows： in the early stage， identify endowment predispositions and regulate body constitution to achieve prevention； in the progressive stage， focus on activating blood circulation to resolve stasis， reinforcing healthy

， and removing toxin， with modifications based on syndrome differentiation； in the late stage， promote detoxification and dredge obstructions while preserving primordial qi to manage critical and variable conditions.

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references

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