Clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of acute lateral ankle ligament injury

PENG Hongkai; CHENG Ting; WANG Hongjie; QIU Jiaming; QI Guodong; WEI Yifei; HAO Zehan; XUE Zi'ang

doi:10.16025/j.1674-1307.2025.10.007

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Clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of acute lateral ankle ligament injury

更新时间：2025-12-15

- Clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of acute lateral ankle ligament injury
- Beijing Journal of Traditional Chinese Medicine Vol. 44, Issue 10, Pages: 1259-1264(2025)
- 作者机构：
  
  中国中医科学院望京医院骨关节二科，北京 100102
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2025.10.007
  CLC：
- Received：16 March 2025，
  
  Published：25 October 2025
- 稿件说明：
移动端阅览
彭洪凯，程桯，王宏杰，等.中西医结合治疗急性外踝韧带损伤的疗效观察［J］.北京中医药，2025，44（10）：1259-1264.

PENG Hongkai,CHENG Ting,WANG Hongjie,et al.Clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of acute lateral ankle ligament injury[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1259-1264.
彭洪凯，程桯，王宏杰，等.中西医结合治疗急性外踝韧带损伤的疗效观察［J］.北京中医药，2025，44（10）：1259-1264. DOI： 10.16025/j.1674-1307.2025.10.007.

PENG Hongkai,CHENG Ting,WANG Hongjie,et al.Clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of acute lateral ankle ligament injury[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1259-1264. DOI： 10.16025/j.1674-1307.2025.10.007.

摘要

目的

观察中医疗法联合POLICE原则（支具保护、适当负重、冰敷、加压包扎、抬高患肢）治疗急性外踝韧带损伤的临床疗效。

方法

纳入2024年6月—2025年2月于中国中医科学院望京医院就诊的急性外踝韧带损伤患者60例，用随机数字表法分为观察组和对照组各30例。2组患者均应用POLICE原则处理，对照组予双氯芬酸二乙胺乳胶剂外用，观察组予中医综合疗法，疗程3周。嘱患者于伤后4~6周进行踝关节康复训练。比较2组患者治疗前、伤后3周、伤后6周的美国足踝外科踝功能（AOFAS）评分、Karlsson评分，以及2组患者治疗前、伤后3个月的患侧踝关节磁共振成像（MRI）评分，并测量距腓前韧带区域信噪比（SNR）。

结果

伤后3周，观察组AOFAS、Karlsson评分均高于对照组（

0.05），伤后3个月SNR低于对照组（

0.05）。2组治疗期间均未发生晕针、滞针等针刺相关反应；2组治疗期间及治疗结束后1周均未发现患侧踝关节皮肤红肿、瘙痒等局部反应，也未发生晕针、滞针等针刺相关反应。

结论

中医疗法联合POLICE原则的疗法有助于急性外踝韧带损伤患者踝关节韧带修复及关节功能恢复，且安全性高。

Abstract

Objective

To observe the clinical efficacy of traditional Chinese medicine （TCM） therapy combined with the POLICE principle （Protection with brace， Optimal Loading， Ice， Compression， Elevation） in treating acute lateral ankle ligament injury.

Methods

Sixty patients with acute lateral ankle ligament injury treated at Wangjing Hospital of China Academy of Chinese Medical Sciences from June 2024 to February 2025 were enrolled and randomly divided into an observation group and a control group， with 30 patients in each group， using a random number table. Both groups received POLICE principle-based management. The control group was treated with topical diclofenac diethylamine emulgel， while the observation group received comprehensive TCM therapy. The treatment course was 3 weeks. Patients were instructed to undergo ankle rehabilitation training 4–6 weeks post-injury. The American Orthopaedic Foot & Ankle Society （AOFAS） score and Karlsson score were assessed before treatment， at 3 weeks post-injury， and at 6 weeks post-injury. MRI scores of the affected ankle and the signal-to-noise ratio （SNR） in the anterior talofibular ligament region were measured before treatment and at 3 months post-injury.

Results

At 3 weeks post-injury， the observation group had significantly higher AOFAS and Karlsson scores than the control group （

0.05）. At 3 months post-injury， SNR in the observation group was lower than that in the control group （

0.05）. No acupuncture-related adverse reactions such as dizziness or needle retention were observed during the treatment period. No local reactions such as redness， swelling， or itching of the affected ankle were obs

erved during the treatment or within 1 week after treatment completion.

Conclusion

TCM therapy combined with the POLICE principle facilitates ligament repair and functional recovery of the ankle in patients with acute lateral ankle ligament injury and demonstrates a favorable safety profile.

关键词

Keywords

references

SMITH MD , VICENZINO B , BAHR R , et al . Return to sport decisions after an acute lateral ankle sprain injury: introducing the PAASS framework-an international multidisciplinary consensus [J ] . Br J Sports Med , 2021 , 55 ( 22 ): 1270 - 1276 .

SWANSON B , HEWITT MA , BUCKLEY SE , et al . Epidemiology of ankle ligament injuries in US high school athletes [J ] . Foot Ankle Orthop , 2022 , 7 ( 4 ): 2473011421S00961 .

ZHOU Z , ZHOU H , JIE T , et al . Analysis of stress response distribution in patients with lateral ankle ligament injuries: a study of neural control strategies utilizing predictive computing models [J ] . Front Physiol , 2024 , 15 : 1438194 .

外踝韧带损伤的中西医结合治疗专家共识 [J ] . 中华骨科杂志 , 2019 ( 11 ): 653 - 659 .

VAN DEN BEKEROM MP , STRUIJS PA , BLANKEVOORT L , et al . What is the evidence for rest,ice,compression,and elevation therapy in the treatment of ankle sprains in adults [J ] . J Athl Train , 2012 , 47 ( 4 ): 435 - 443 .

邓晋丰 , 钟广玲 , 刘金文 . 骨伤科专病中医临床诊治 [M ] . 北京 : 人民卫生出版社 , 2000 : 89 - 90 .

许怀来 , 雷仲民 , 刘义辉 , 等 . 近十年中西医治疗急性踝关节扭伤的研究进展 [J ] . 现代中西医结合杂志 , 2021 , 30 ( 31 ): 3516 - 3520 .

朱小静 , 梁渤 , 许奎军 , 等 . 中药塌渍技术及针刺联合中频干扰电疗治疗非特异性腰痛的临床疗效 [J ] . 北京中医药 , 2023 , 42 ( 6 ): 692 - 695 .

彭洪凯 , 程桯 , 王宏杰 , 等 . 中医综合疗法联合POLICE原则用于急性踝关节扭伤的疗效观察 [J ] . 中国中医基础医学杂志 , 2025 , 31 ( 10 ): 1838 - 1843 .

COUGHLIN MJ , SALTZMAN CL , ANDERSON RB . 曼氏足踝外科学 [M ] . 9版 .唐康来,徐林译. 北京 : 人民卫生出版社 , 2015 : 1482 - 1485 .

BLEAKLEY CM , GLASGOW P , MACAULEY DC . PRICE needs updating, should we call the POLICE [J ] . Br J Sports Med , 2012 , 46 ( 4 ): 220 - 221 .

韩庆欣 , 张磊 , 吴俊莹 , 等 . 急性外踝韧带损伤三期中药外治方案的早期临床疗效观察 [J ] . 中国骨伤 , 2024 , 37 ( 10 ): 997 - 1002 .

温鑫柱 , 黄江海 , 方志远 , 等 . 摇拔戳手法治疗急性踝关节外侧韧带损伤的临床研究 [J ] . 中国中医骨伤科杂志 , 2023 , 31 ( 5 ): 49 - 53,59 .

裴守科 , 夏兆云 , 田忠祥 , 等 . 3.0T MRI常规扫描与优化扫描在外踝韧带训练伤中的应用价值比较 [J ] . 中国骨与关节杂志 , 2021 , 10 ( 11 ): 806 - 810 .

LIU W , LI H , HUA Y . Quantitative magnetic resonance imaging(MRI)analysis of anterior talofibular ligament in lateral chronic ankle instability ankles pre-and postoperatively [J ] . BMC Musculoskelet Disord , 2017 , 18 ( 1 ): 397 .

MARICOT A , DICK E , WALRAVENS A , et al . Brain neuroplasticity related to lateral ankle ligamentous injuries:a systematic review [J ] . Sports Med , 2023 , 53 ( 7 ): 1423 - 1443 .

张冰颖 , 张霄瀚 , 钱驿 , 等 . 急性闭合性软组织损伤处理原则的研究进展 [J ] . 中国医学科学院学报 , 2024 , 46 ( 6 ): 828 - 835 .

DU R , SUN W , HE F , et al . Early weight-bearing rehabilitation protocol after anterior cruciate ligament reconstruction [J ] . J Vis Exp , 2024 ( 1 ): 205 .

GLASGOW P , PHILLIPS N , BLEAKLEY C . Optimal loading: key variables and mechanisms [J ] . Br J Sports Med , 2015 , 49 ( 5 ): 278 - 279 .

MOHRIAK R , MANSUR NS , ALLOZA JFM . Correlation between muscle strength asymmetry and its impact on functional scores after ankle sprain rehabilitation [J ] . Foot Ankle Orthop , 2022 , 7 ( 4 ): 2473011421S00819 .

DUBOIS B , ESCULIER JF . Soft-tissue injuries simply need PEACE and LOVE [J ] . Br J Sports Med , 2020 , 54 ( 2 ): 72 - 73 .

ZARE P , GHORAISHIAN M , FAGHIH KHORASANI A . A three-dimensional model of transient bioheat transfer in the lower extremity during cryotherapy [J ] . Proc Inst Mech Eng H , 2021 , 235 ( 12 ): 1413 - 1420 .

GADDI D , MOSCA A , PIATTI M , et al . Acute ankle sprain management: an umbrella review of systematic reviews [J ] . Front Med (Lausanne) , 2022 ( 9 ): 868474 .

JONES P , DALZIEL SR , LAMDIN R , et al . Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury [J ] . Cochrane Database Syst Rev , 2015 ( 7 )： CD007789 .

STOVITZ SD , JOHNSON RJ . NSAIDs and musculoskeletal treatment:what is the clinical evidence [J ] . Phys Sportsmed , 2003 , 31 ( 1 ): 35 - 52 .

李敏 , 王斌 , 唐志书 , 等 . 芒硝及其主成分抗炎镇痛泻下效应差异研究 [J ] . 中药药理与临床 , 2012 , 28 ( 5 ): 55 - 57 .

TAO L , FU J , WANG F , et al . The application of mirabilite in traditional Chinese medicine and its chemical constituents,processing methods,pharmacology,toxicology and clinical research [J ] . Front Pharmacol , 2023 ( 14 ): 1293097 .

张会凡 , 杨琼 , 詹丽娥 . 消肿止痛酊结合冷敷在骨伤科中的应用 [J ] . 中国当代医药 , 2015 , 22 ( 10 ): 143 - 145 .

吴俊德 , 马占华 , 陈兆军 . 基于"筋骨平衡"理论探讨慢性踝关节不稳的临床诊治 [J ] . 北京中医药 , 2023 , 42 ( 12 ): 1370 - 1372 .

黄麒麟 , 陈国群 . 针刺“五虎穴”配合摇拔戳手法治疗急性踝关节扭伤的疗效观察 [J ] . 广州中医药大学学报 , 2025 , 42 ( 09 ): 2206 - 2211 .

宋晓琳 , 苏布衣 , 刘思妤 , 等 . 针刺运动结合局部针刺疗法对训练性膝关节损伤的疗效观察 [J ] . 北京中医药 , 2025 , 44 ( 4 ): 440 - 444 .

LIU AF , GONG SW , CHEN JX , et al . Efficacy and safety of acupuncture therapy for patients with acute ankle sprain:a systematic review and meta-analysis of randomized controlled trials [J ] . Evid Based Complement Alternat Med , 2020 : 9109531 .

柳杨 , 龚庆 , 赵文海 . 针刺养老穴结合运动治疗急性外踝关节扭伤30例临床观察 [J ] . 中国民族民间医药 , 2023 , 32 ( 7 ): 115 - 118 .

李思慧 , 刘书庆 , 王玥梅 , 等 . 阳陵泉穴功效主治及生物学机制研究进展 [J ] . 按摩与康复医学 , 2023 , 14 ( 4 ): 56 - 59 .

胡付聪 , 王振国 . 踝关节外侧副韧带损伤的MRI影像特征及其诊断价值 [J ] . 现代医用影像学 , 2025 , 34 ( 1 ): 89 - 91 .

SCHMID N , SCHÜLE S , RIENECKER M , et al . Low-dose computed tomography arthrography using tin-filter technology:advancing high-resolution cartilage evaluation in the ankle joint [J ] . Acad Radiol , 2025 , 32 ( 8 ): 4733 - 4740 .

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