ZHANG Hongyu,LI Yiping,LUO Wanting,et al.XU Xian's experience in differentiating and treating prurigo nodularis based on the principle of the stagnation of yin and yang[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1303-1306.
ZHANG Hongyu,LI Yiping,LUO Wanting,et al.XU Xian's experience in differentiating and treating prurigo nodularis based on the principle of the stagnation of yin and yang[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1303-1306. DOI: 10.16025/j.1674-1307.2025.10.014.
XU Xian's experience in differentiating and treating prurigo nodularis based on the principle of the stagnation of yin and yang
Prurigo nodularis is a psychogenic disease characterized by itching and nodules as its main clinical manifestations. Professor XU Xian explores its etiology, pathogenesis, and diagnostic and therapeutic approaches from the perspective of the theory of
Yinyang
stagnation. He holds that when itching is more severe, the disorder lies in
yang
. Specifically,
qi
stagnation arises first, and sta
gnation leads to knotting, generating dampness and blood stasis, which constitutes
yin
stagnation within
yang
. When nodules are more prominent, the disorder lies in
yin
. Specifically, dampness and blood stasis congeal and bind, and knotting gives rise to stagnation, which further leads to
qi
disorder, representing
yang
stagnation within
yin
. "
Yinyang
stagnation, stagnation causing knotting, and knotting causing further stagnation" is the key to the lingering, recurrent nature of the disease. On this basis, the therapeutic principle of "promoting
qi
to relieve stagnation and regulating the blood to disperse nodules" is proposed, with the goals of alleviating itching and eliminating nodules. At the initial stage of nodule formation, promoting
qi
to relieve stagnation prevents the progression toward phlegm and blood stasis. When nodules become stubborn and indurated, regulating the blood to disperse nodules prevents
qi
disorder, allowing stagnation to be relieved and knots to be dispersed, thereby achieving harmony between
qi
and blood and mutual integration of
yin
and
yang
.
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references
HUANG AH , WILLIAMS KA , KWATRA SG . Prurigo nodularis: epidemiology and clinical features [J ] . J Am Acad Dermatol , 2020 , 83 ( 6 ): 1559 - 1565 .