GONG Jin,CHEN Yiyao,REN Xuelei,et al.Traditional Chinese medicine syndrome differentiation and treatment of idiopathic membranous nephropathy based on the theory of "caused by additions"[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1351-1354.
GONG Jin,CHEN Yiyao,REN Xuelei,et al.Traditional Chinese medicine syndrome differentiation and treatment of idiopathic membranous nephropathy based on the theory of "caused by additions"[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1351-1354. DOI: 10.16025/j.1674-1307.2025.10.025.
Traditional Chinese medicine syndrome differentiation and treatment of idiopathic membranous nephropathy based on the theory of "caused by additions"
The concept of "caused by additions" refers to the combined effect of pre-existing pathogenic factors and new infections that lead to disease. Subsequent generations of physicians expanded this idea to include theories such as combined pathogenic factors, latent pathogenic factors, and multiple causes of disease, emphasizing a holistic and dynamic view of the onset of illness. The pathogenesis of idiopathic membranous nephropathy (IMN) remains incompletely understood, but it is closely related to factors such as genetic predisposition and environmental influences. External infections often worsen or trigger relapses of the condition, which aligns with the essence of "caused by additions", emphasizing the accumulation of multiple factors leading to disease. Based on the "caused by additions" theory, the pathogenesis of IMN involves two main aspects: deficiency of healthy
qi
and excess of pathogenic factors, often resulting from a combination of multiple pathogenic factors. Treatment focuses on dispersing external wind and relieving internal wind, strengthening the spleen and tonifying the kidneys to support healthy
qi
and reinforce vitality, activating blood circulation and resolving stasis, eliminating dampness and removing toxins, and clearing heat and soothing the throat.
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