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Efficacy evaluation study on the treatment of rhinitis medicamentosa with nasal corticosteroids combined with traditional Chinese medicine nasal irrigation
- Beijing Journal of Traditional Chinese Medicine Vol. 45, Issue 1, Pages: 16-21(2026)
- 作者机构：
中国中医科学院望京医院耳鼻喉科，北京 100102
- 作者简介：
- 基金信息：
DOI：10.16025/j.1674-1307.2026.01.004
CLC：Received：09 May 2025，
Published：25 January 2026
- 稿件说明：
移动端阅览
王晓瑞，夏睿琪，刘怡陶，等.鼻用皮质类固醇联合中药鼻腔冲洗治疗肺脾气虚型药物性鼻炎的疗效观察［J］.北京中医药，2026，45（1）：16-21.
WANG Xiaorui,XIA Ruiqi,LIU Yitao,et al.Efficacy evaluation study on the treatment of rhinitis medicamentosa with nasal corticosteroids combined with traditional Chinese medicine nasal irrigation[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(01):16-21.
王晓瑞，夏睿琪，刘怡陶，等.鼻用皮质类固醇联合中药鼻腔冲洗治疗肺脾气虚型药物性鼻炎的疗效观察［J］.北京中医药，2026，45（1）：16-21. DOI： 10.16025/j.1674-1307.2026.01.004.
WANG Xiaorui,XIA Ruiqi,LIU Yitao,et al.Efficacy evaluation study on the treatment of rhinitis medicamentosa with nasal corticosteroids combined with traditional Chinese medicine nasal irrigation[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(01):16-21. DOI： 10.16025/j.1674-1307.2026.01.004.
摘要
目的
2
观察鼻用皮质类固醇联合中药鼻腔冲洗治疗肺脾气虚型药物性鼻炎的疗效。
方法
2
纳入2023年9月1日—2024年12月31日在中国中医科学院望京医院耳鼻喉科确诊的RM肺脾气虚证患者84例，依据随机数字表法分为对照组和观察组各42例。对照组采用盐水鼻腔冲洗联合鼻用皮质类固醇治疗，观察组采用加味玉屏风散鼻腔冲洗联合鼻用皮质类固醇治疗，连续治疗2周，随访3个月。治疗前后采用VAS评分评价鼻塞严重程度，用鼻阻力仪和鼻声反射仪测量双侧鼻腔有效阻力（R
有效
）、距前鼻孔0~7 cm的鼻腔容积（V
7
），用鼻腔鼻窦结局测试-20（SNOT-20）评分评估症状，治疗结束后3个月内定期随访统计减充血剂复用率，统计治疗期间2组发生的不良反应，比较疗效。
结果
2
观察组总有效率为92.9%，高于对照组的76.2%（
P
<
0.05）。与治疗前比较，治疗后2组鼻塞VAS评分均降低（
P
<
0.05），且观察组鼻塞VAS评分低于对照组（
P
<
0.05）。与治疗前比较，治疗后2组R
有效
均降低（
P
<
0.05），且观察组R
有效
低于对照组（
P
<
0.05）；治疗后2组V
7
均升高（
P
<
0.05），且观察组V
7
高于对照组（
P
<
0.05）。与治疗前比较，治疗后2组SNOT-20评分均降低（
P
<
0.05），且观察组SNOT-20评分低于对照组（
P
<
0.01）。观察组减充血剂复用3例（7.7%），对照组为9例（28.1%），2组比较差异有统计学意义（
P
<
0.05）。治疗期间，2组均未发生不良反应。
结论
2
加味玉屏风散鼻腔冲洗联合鼻用皮质类固醇治疗药物性鼻炎疗效优于盐水鼻腔冲洗联合鼻用皮质类固醇，能够显著降低患者对减充血剂的依赖并改善其生活质量。
Abstract
Objective
2
To evaluate and compare the efficacy of nasal irrigation with
Jiawei Yupingfeng
and saline combined with nasal corticosteroids in the treatment of rhinitis medicamentosa.
Methods
2
A prospective controlled study was conducted at Wangjing Hospital of China Academy of Traditional Chinese Medicine from September 2023 to December 2024. The study included 84 patients diagnosed with Rhinitis medicamentosa and treated during this period. Patients were randomly divided into two groups： a saline rinse group and a traditional Chinese medicine rinse group. The randomization method used was a numerical table method. The saline rinse group was treated with saline nasal irrigation combined with nasal corticosteroids， while the traditional Chinese medicine rinse group was treated with
Jiawei Yupingfeng
nasal irrigation combined with nasal corticosteroids. The patients were followed up for a period of one month. The patients in the Chinese medicine rinsing group underwent a 2-week course of nasal irrigation with Jiawei yupingfeng in conjunction with nasal corticosteroids， followed by a 3-month follow-up period. The Visual Analog Scale of Nasal Congestion （VAS）， the Nasal Resistive Index （NRI）， the Nasal Acoustic Reflex （NAR）， and the sinuses outcome test-20（SNOT-20） were compared and analyzed before and after treatment for the two groups.
Results
2
The total effective rate of treatment in the Chinese medicine flushing group （92.7%） was higher than that in the saline flushing group （76.2%）， and the difference was statistically significant （
P
<
0.05）； the rate of decongestant reuse in the Chinese medicine flushing group （7.7%） was lower than that of decongestant reus
e in the saline flushing group （28.1%） and the difference was statistically significant （
P
<
0.05）； Compared with before treatment， VAS score， SNOT-20 score and effective resistance of nasal cavity decreased （
P
<
0.05）， and nasal cavity volume increased significantly （
P
<
0.05）. The VAS score of nasal obstruction ，nasal effective resistance and nasal volume 0-7cm from nostril were not significantly different between the two groups before treatment （
P
>
0.05）. After treatment， the VAS score of nasal obstruction，the SNOT-20 score， nasal effective resistance in the Chinese medicine irrigation group were significantly lower than those in the saline irrigation group （
P
<
0.05）， and nasal volume 0-7cm from nostril in the Chinese medicine irrigation group was significantly higher than that in the saline irrigation group （
P
<
0.05）.
Conclusion
2
Jiawei Yupingfeng
nasal irrigation combined with nasal corticosteroids therapy is better than saline nasal irrigation combined with Nasal corticosteroids therapy， which significantly reduced the patients' dependence on decongestants and significantly improved their quality of life.
关键词
Keywords
references
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