最新刊期
期 8 ， 2022
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- 摘要：ObjectiveTo investigate the relationship between bone marrow edema（BME） on sacroiliac joints（SIJ）and TCM syndromes in male patients with ankylosing spondylitis （AS） and risk factors for BME on SIJ.Methods143 male AS patients treated in outpatient and inpatient departments of TCM Rheumatology in China-Japan Friendship Hospital from August 2017 to December 2021 were selected and according to the MRI of Sacroiliac Joint Canadian Association for the Study of Spinal Arthritis （SPARCC）， the patients were divided into sacroiliac joint bone marrow edema group （SPARCC score ≥2， bone marrow edema group） and none sacroiliac joint bone marrow edema group （SPARCC score < 2， none bone marrow edema group） to analyze the differences in disease characteristics of two groups of patients with or without BME on SIJ MRI， and the risk factors for BME on SIJ MRI by logistic regression.ResultsKidney deficiency and dampness heat syndrome was more common in male AS patients in bone marrow edema group，and kidney deficiency and cold syndrome in Du meridian in male AS patients in none bone marrow edema group； compared with none bone marrow edema group， the HLA-B27 positivity rate，ESR and CRP levels were significantly higher in bone marrow edema group （P<0.05）. Multivariate logistic regression analysis showed that kidney deficiency and dampness heat syndrome， HLA-B27 positivity and ESR were risk factors for BME on SIJ MRI （SPARCC score ≥2） in male AS patients （P < 0.05）.ConclusionSevere BME on SIJ in male AS patients is more likely to be associated with kidney deficiency and dampness heat syndrome. Kidney deficiency and dampness heat syndrome，HLA-B27 positivity and ESR level are risk factors for inflammation on SIJ with male AS.关键词：Male;ankylosing spondylitis;TCM syndrome;magnetic resonance imaging;bone marrow edema
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发布时间：2023-02-15 - 摘要：ObjectiveTo investigate the clinical efficacy of Bushen Qiangdu Qinghua Decoction on ankylosing spondylitis （AS） of kidney deficiency and dampness heat syndrome.MethodsUsing a single-blind， randomized controlled study method， 70 patients with kidney deficiency and dampness heat syndrome of AS were randomly divided into observation and control groups according to random number table method. The observation group was treated with Bushen Qiangdu Qinghua Decoction combined with celecoxib， while the control group was treated with Chinese herbal medicine placebo combined with celecoxib. The course of treatment was 2 weeks for both groups. The clinical symptoms and signs， TCM symptom scores， disease activity， inflammatory response indexes of the two groups were evaluated before and after the treatment， and the clinical efficacy of Bushen Qiangdu Qinghua Decoction was assessed using the evaluation system of efficacy criteria developed by the working group of AS International Assessment Committee （ASAS）， namely ASAS20， ASAS40， ASAS5/6， BASDAI50 and the improvement rate of TCM symptom scores.ResultsAfter 12 weeks of treatment，the ASAS20 response rate was 73.5% and 44.1% in the observation group and the control group respectively； ASAS40 response rate was 47.1% and 17.6% respectively； ASAS5/6 response rate was 52.9% and 23.5% respectively； the total TCM effective rate was 91.88% and 55.88% respectively， and the differences of above indexes between the two groups were statistically significant （P<0.05）. After treatment， BAS-G， BASDAI， ASDAS-CRP， BASFI， nocturnal pain VAS score， spinal pain VAS score， TCM evidence score， laboratory index of AS patients in both groups were significantly improved compared with those before treatment， and the differences were statistically significant （P<0.05）； compared two groups， BAS-G， BASDAI， ASDAS-CRP nocturnal pain， TCM symptoms scores in the observation group were better than those in the control group， and the differences were statistically significant （P<0.05）.ConclusionThe clinical efficacy of Bushen Qiangdu Qinghua Decoction in the treatment of AS with kidney deficiency and dampness heat syndrome is significantly better than that of celecoxib with less adverse effects and high safety.关键词：Bushen Qiangdu Qinghua Decoction;ankylosing spondylitis;kidney deficiency and dampness heat syndrome;efficacy evaluation
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发布时间：2023-02-15 -
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- 摘要：ObjectiveTo investigate the current status of frailty and its correlation with TCM syndromes among the elderly who visited the Department of TCM of General Hospitals in Beijing.MethodsConvenience sampling method was used to collect the basic data of the elderly who visited the department of traditional Chinese medicine of one of the general hospitals in seven urban areas of Beijing from January 2021 to July 2021， and "FI-IM" was used to evaluate frailty， TCM syndrome differentiation was made.Results1 052 effective questionnaires were obtained. Of them，179（17.0%） were not frail，267（25.4%） were pre-frail， and 606（57.6%） were frail. IM-FI： female> male；heavy manual workers were lower than medium manual workers and light manual workers， and non-manual workers；the worse the degree of self-care，that is， the higher the physical disability， the higher the index IM-FI；it was positively correlated with allergy history，living alone history，multiple medication， long-term pain history， and chronic disease history. The population with IM-FI of western medicine，TCM and integrated TCM and western medicine was higher than that of no intervention（P<0.05）.The top 5 chronic diseases were hypertension （508 cases，48.29%）， dyslipidemia （302 cases，28.71%）， coronary heart disease （290 cases，27.57%）， diabetes （280 cases，26.62%）， chronic gastritis （196 cases，18.63%）. The top 5 symptoms were forgetfulness，fatigue，frequent nocturia，shortness of breath，and insomnia. Qi-deficiency syndrome was the main syndrome element of the elderly cases with non-frailty， pre-frailty and frailty， accounting for 60.30% to 70.62%； blood stasis syndrome accounted for 44.57% and 58.42% respectively in pre-frailty and frailty；phlegm-turbid syndrome was the second common element of the non-frailty，accounting for 44.13%. This study involved 213 TCM syndromes，the top 3 were Qi deficiency and phlegm turbidity syndrome，Qi deficiency and blood stasis syndrome，and Yin deficiency and heat syndrome. There were 52 types of syndromes in the non-frailty group， and the qi deficiency and phlegm turbidity syndrome accounted for 20.67%. Among 93 types in pre-frailty group，10.11% of Qi deficiency and blood stasis syndrome and 9.36% of Qi deficiency and phlegm syndrome were in the top two positions； among 188 types of the frailty group， multiple and complex syndromes were more commonly seen， and no syndrome accounted for more than 5%. In "IM-FI"， the percentage of yang deficiency syndrome was the highest，followed by blood deficiency syndrome，qi stagnation syndrome， blood stasis syndrome and damp syndrome. Intervention methods of integrated TCM and western medicine were highly accepted among the elderly.ConclusionThe degree of frailty of the elderly in the Department of TCM of Beijing's general hospitals is significantly correlated with the gender，age，occupation type，living alone status，allergy history， multiple medication， long-term pain， self-care level， TCM intervention， and common diseases of the elderly；the frail elderly more suffer from multiple system diseases， TCM syndromes of the frail elderly are complex and diverse，and the more syndromes are complicated，the higher the degree of frailty； the blood stasis syndrome may be an important factor affecting the frailty of the elderly；the integration of TCM and western medicine is the main mean to intervene frailty in the elderly.关键词：Senile patient;frailty;Beijing;general hospital;Department of Traditional Chinese Medicine;TCM syndromes
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发布时间：2023-02-15 - 摘要：ObjectiveTo explore TCM syndrome elements characteristics in patients with neurogenic orthostatic hypotension （nOH） combined with supine hypertension （SH）.Methods160 patients with nOH were enrolled， and were divided into nOH group （82 cases） and nOH+SH group （78 cases） according to whether they were complicated with SH or not. The two groups of patients were scored by TCM syndrome element scoring table to make comparison，and the risks of each syndrome element to SH was analyzed.ResultsIn terms of the distribution of syndrome elements，the disease location elements of the two groups were brain，spleen，kidney and liver，and there was no significant difference between the two groups （P>0.05）. Among the disease nature，the syndrome elements with higher frequency were qi deficiency，myelopathy，liver wind and phlegm turbidity syndrome in both two groups. The proportion of phlegm turbidity syndrome and blood stasis syndrome in nOH+SH group was higher than that in nOH group （P<0.05）， and blood stasis syndrome was more significant（P<0.05）. Syndrome factor integral，the scores of phlegm turbid syndrome， blood stasis syndrome， liver wind syndrome scores in nOH+SH group were higher than those in nOH group（P<0.05）， and phlegm turbid syndrome， blood stasis syndrome was more significant（P<0.01）. Logistic regression analysis showed that the syndrome elements of myelopathy syndrome，phlegm turbid syndrome，blood stasis syndrome and the occurrence of SH were related （P<0.05），the OR values were 0.037，8.504 and 12.721 respectively.ConclusionBrain is the main location element in patients with nOH combined with SH， and but the spleen，kidney and liver are also involved. The main disease elements are qi deficiency syndrome，marrow reduction syndrome，liver wind syndrome，phlegm turbidity syndrome and blood stasis syndrome. Phlegm turbidity syndrome and blood stasis syndrome may be the risk factors of SH in nOH patients.关键词：Neurogenic orthostatic hypotension;supine hypertension;TCM syndrome elements
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发布时间：2023-02-15 - 摘要：ObjectiveTo observe the effect of Feixin'an in treating chronic obstructive pulmonary disease （COPD） of deficiency of Qi and Yin in the stable stage.MethodsA total of 60 COPD patients in stable stage of deficiency of Qi and Yin with Grade II to Ⅲ lung function treated in Department of TCM of Beijing Chaoyang Hospital Affiliated to the Capital Medical University from January 2019 to December 2020 were randomly divided into a control group and an observation group with 30 cases in each group. The control group was treated with routine western medicine. On the basis of the routine western medicine，the observation group was also given Feixin'an with one bag each time， twice a day，12 weeks as a course， and follow-up for 6 months. The TCM clinical syndromes score， CAT score，mMRC score， acute aggravation times， laboratory indexes and adverse reactions in 2 groups were observed and compared before and after the treatment.ResultsThe effective rate of the observation group was 96.67%， which was higher than that of the control group（P<0.05）which was 83.33%， and the difference was statistically significant （P<0.05）. After the treatment， TCM clinical syndromes score， CAT score， mMRC score and HIF-1α were more obviously alleviated than that before the treatment（P<0.05）， serum 1，25-dihydroxyvitamin D3［1，25（OH）2D3］ were increased than that before the treatment in both two groups， the index of the experimental group was better than that of the control group and the difference was statistically significant （P<0.05） No adverse reactions were found in both groups.ConclusionFeixin'an combined with routine treatment can enhance the clinical effect of chronic obstructive pulmonary disease （COPD） of deficiency of Qi and Yin in the stable stage， improve TCM symptoms，reduce the acute aggravation and improve the quality of life.关键词：Feixin'an;chronic obstructive pulmonary disease;stable stage;Qi and Yin deficiency
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发布时间：2023-02-15 - 摘要：ObjectiveTo observe the clinical effect of Qianli Fumigation Recipe combined with meibomian gland massage in the treatment of dry eye （DE） related to obstructive meibomian gland dysfunction （OMGD）.MethodsUsing random number table method，150 patients with mild to moderate dry eye related to OMGD were divided into a control group and a treatment group of 75 cases each. Both groups were treated with 0.1% pranoprofen， 0.1% sodium hyaluronate eye drops and meibomian gland massage. Meanwhile，the treatment group was also treated with fumigation by Qianli Fumigation Recipe，while the control group was treated with distilled water fumigation. Two groups of patients received one month of treatment as one course. Later，the overall efficacy and changes of OSDI score，BUTf，BUTav，TMH，meibomian gland score，eye red analysis and FSS of two groups were measured and evaluated.ResultsAfter treatment，the total effective rate of the treatment group was 91.79%，which was significantly higher than 65.75% of the control group（P<0.05）. Compared with the control group，OSDI score， meibomian gland score，eye red analysis and FSS of the treatment group were significantly reduced. BUTf，BUTav and TMH of the treatment group were significantly increased（P<0.05）.ConclusionQianli Fumigation Recipe combined with meibomian gland massage can effectively alleviate the subjective and objective symptoms of DE related to OMGD，increase the secretion of tear fluid，prolong tear film rupture time，restore tear film stability，improve ocular surface microscopy environment，and restore the normal regulation of meibomian glands on meibomian esters.关键词：Dry eye related to OMGD;Qianli Fumigation Recipe;meibomian gland massage
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发布时间：2023-02-15 - 摘要：ObjectiveTo explore the curative effects of harmonizing method of traditional Chinese medicine on senile patients with chronic stable angina pectoris．Methods64 cases of senile patients with chronic stable angina pectoris were randomly divided into two groups．The control group was treated by baseline treatment．The treatment group was treated by Chinese herbal medicines with harmonizing and relieving paralysis actions on the basis of the control group. Both groups were treated twice daily，and the treatment course was 8 weeks．The clinical efficacy， cardiopulmonary exercise function， nitroglycerin consumption and safety of two groups were compared before and after treatment．ResultsAfter treatment，the total effective rate of symptoms in the treatment group was higher than that in the control group（P<0.05）. There was no statistical difference in the total effective rate of ECG between the two groups（P>0.05）. The oxygen pulse max（VO2/HRmax），peak oxygen uptake（PeakVO2），AT，max exercise time in treatment group after the treatment were significantly improved than those before the treatment（P<0.05）with the difference statistically significant（P<0.05）；VO2/HRmax/HRmax and AT increased after the treatment in control group with the difference statistically significant（P<0.05），while there was no statistical difference on PeakVO2 and max exercise time after the treatment（P>0.05）．VO2/HRmax， PeakVO2 and AT in the treatment group were higher than those in the control group（P<0.05） with the difference statistically significant. There was no significant difference in maximum exercise time between the two groups（P>0.05）. The stopping rate of nitroglycerin in treatment group was higher than that in control group， and the difference was statistically significant（P<0.05）. There was no adverse reactions in two groups during treatment.ConclusionTCM Harmonizing method used for senile patients with chronic stable angina pectoris is safe and effective in improving clinical symptoms， enhancing cardiopulmonary function and nitroglycerin stopping rate．关键词：Chinese herbal medicines for harmonizing and relieving paralysis;chronic stable angina pectoris;cardiopulmonary exercise testing;old people
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发布时间：2023-02-15 -
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