Objectve A clinical research was carried out through an orthogonal design test， in which the best scheme was selected from the clinical schemes for intervention of sepsis high fever with different factor levels of Chinese medicine collapse stain.

Methods

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90 sepsis patients who met the inclusion criteria were randomly divided into 9 groups according to the orthogonal design table. The concentration of the drug solution， the temperature of the drug solution， the humidity of the stained gauze， and the stained area were used as factors. Each factor was set at three levels and randomly divided into nine groups of experiments arranged in the L9 （34） orthogonal table. All enrolled patients received traditional Chinese medicine stain intervention for 1 hour with 4 hours as one course of treatment. The effectiveness of technical intervention was evaluated by observing changes in bladder temperature in patients.

Results

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The best plan for using traditional Chinese medicine stain to intervene sepsis with high fever was to use Chinese medicine solution with a concentration of 0.3 g/mL and a temperature of 25~30 ℃. The humidity of the stained gauze should be ≥80%， and the stained area should be the Stomach Meridian of Foot Yangming and the Large Intestine Meridian of Hand Yangming.

Conclusion

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The optimal solution for traditional Chinese medicine stain obtained through orthogonal experimental method can improve the effectiveness of clinical intervention for sepsis with high fever，as it could achieve rapid reduction of human body temperature， reduce adverse reactions during the process， save medical resources， reduce patient economic burden， and ultimately achieve the goal of improving patient compliance and satisfaction with the treatment plan for traditional Chinese medicine stain.