1.北京中医药大学研究生院,北京 100029
2.北京中医药大学东直门医院血液肿瘤科,北京 100700
隽文曦,女,23岁,硕士研究生。研究方向:中西医结合治疗血液病、心血管疾病。
张雅月,E-mail: yayuezhang@126.com
收稿:2024-09-05,
纸质出版:2026-01-25
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隽文曦,李潇,陈信义,等.基于陈信义调平理论分期辨治恶性淋巴瘤经验[J].北京中医药,2026,45(1):94-100.
JUAN Wenxi,LI Xiao,CHEN Xinyi,et al.Experience of staged differentiation and treatment of malignant lymphoma based on regulating balance theory proposed by CHEN Xinyi[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(01):94-100.
隽文曦,李潇,陈信义,等.基于陈信义调平理论分期辨治恶性淋巴瘤经验[J].北京中医药,2026,45(1):94-100. DOI: 10.16025/j.1674-1307.2026.01.015.
JUAN Wenxi,LI Xiao,CHEN Xinyi,et al.Experience of staged differentiation and treatment of malignant lymphoma based on regulating balance theory proposed by CHEN Xinyi[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(01):94-100. DOI: 10.16025/j.1674-1307.2026.01.015.
恶性淋巴瘤作为一种常见的恶性肿瘤,其治疗策略一直是医学研究的重点。不同医家对其治疗有不同观点,并提出清热解毒、化痰散结、扶正消癥、补肾固本等多种治法。恶性淋巴瘤的根本病理因素是“痰”,合并“寒”“虚”“瘀”“毒”“滞”等而形成复杂病机。北京中医药大学东直门医院陈信义教授以“中医整体观”为基础,“以平为期”为目标,提出了调平理论,主张通过调整阴阳气机,促进人体恢复脏腑及一身气血津液的平衡。中西医结合治疗恶性淋巴瘤主要分为未接受放化疗的观察期、造血干细胞移植后恢复期和带瘤生存预防复发期。在调平理论指导下对各期的治疗为化痰散结,温阳补正;补肾健脾,培正固本;化痰祛瘀,活血散结。分阶段辨证论治,在提高恶性淋巴瘤患者生活质量、控制病情进展、减少不良反应、延长生存期以及减少复发等方面均获得了显著成效。
Malignant lymphoma, as a common malignant tumor, has long been a focus of medical research with regard to its treatment strategies. Different clinicians hold varying views on its treatment and have proposed multiple therapeutic approaches, including clearing heat and removing toxins, resolving phlegm and dissipating mass, reinforcing the healthy
qi
and eliminating accumulation, and tonifying the kidney to consolidate the root. The fundamental pathological factor of malignant lymphoma is "phlegm", which is often accompanied by "cold", "deficiency", "blood stasis", "toxicity", and "stagnation", forming a complex pathogenesis. Professor CHEN Xinyi of Dongzhimen Hospital, Beijing University of Chi
nese Medicine, based on the holistic view of traditional Chinese medicine (TCM), proposed the regulating balance theory with the connotation of "maintaining equilibrium", advocating the adjustment of
yin-yang
and the
qi
of the five elements to restore the balance of
qi
, blood, and bodily fluids in the Zang-fu organs and the whole body. Integrated treatment of malignant lymphoma combining TCM and Western medicine is mainly divided into three stages, i.e., the observation period without radiotherapy or chemotherapy, the recovery period after hematopoietic stem cell transplantation, and the tumor-bearing survival period for recurrence prevention. Under the guidance of the regulating balance theory, treatment in each stage focuses on dissolving phlegm and dissipating mass, warming
yang
and replenishing healthy
qi
; tonifying the kidney and strengthening the spleen, cultivating healthy
qi
and consolidating the root; and resolving phlegm and blood stasis, activating blood circulation and dissipating mass. Stage-specific syndrome differentiation and treatment have achieved remarkable results in improving the quality of life of patients with malignant lymphoma, controlling disease progression, reducing adverse reactions, prolonging survival, and decreasing recurrence.
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