Clinical effect of Shugan Jianpi Granules on 38 cases of breast cancer-related fatigue with liver depression and spleen deficiency syndrome

NIAN Jia-yun; YU Ming-wei; LI Chen; WANG Xiao-min

doi:10.16025/j.1674-1307.2020.03.026

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Clinical effect of Shugan Jianpi Granules on 38 cases of breast cancer-related fatigue with liver depression and spleen deficiency syndrome

更新时间：2023-04-11

- Clinical effect of Shugan Jianpi Granules on 38 cases of breast cancer-related fatigue with liver depression and spleen deficiency syndrome
- Beijing Journal of Traditional Chinese Medicine Vol. 39, Issue 3, Pages: 283-286(2020)
- 作者机构：
  
  1. 首都医科大学附属北京中医医院肿瘤科
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2020.03.026
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[1]念家云,于明薇,李琛,王笑民.疏肝健脾颗粒治疗38例乳腺癌癌因性疲乏肝郁脾虚证患者的临床疗效[J].北京中医药,2020,39(03):283-286.

NIAN Jia-yun, YU Ming-wei, LI Chen, et al. Clinical effect of Shugan Jianpi Granules on 38 cases of breast cancer-related fatigue with liver depression and spleen deficiency syndrome. [J]. Beijing Journal of Traditional Chinese Medicine 39(3):283-286(2020)
[1]念家云,于明薇,李琛,王笑民.疏肝健脾颗粒治疗38例乳腺癌癌因性疲乏肝郁脾虚证患者的临床疗效[J].北京中医药,2020,39(03):283-286. DOI： 10.16025/j.1674-1307.2020.03.026.

NIAN Jia-yun, YU Ming-wei, LI Chen, et al. Clinical effect of Shugan Jianpi Granules on 38 cases of breast cancer-related fatigue with liver depression and spleen deficiency syndrome. [J]. Beijing Journal of Traditional Chinese Medicine 39(3):283-286(2020) DOI： 10.16025/j.1674-1307.2020.03.026.

摘要

目的观察疏肝健脾颗粒剂（Shugan Jianpi Granule,SGJP）治疗乳腺癌癌因性疲乏（breast cancer related fatigue,BCRF）的临床疗效。方法采用单臂临床试验方法,纳入40例BCRF肝郁脾虚证患者,服用SGJP 8周,观察治疗前及治疗后4、8、12周Piper疲乏自评量表（PFS）、体能状况（ECOG）评分、中医证候量表、综合性医院焦虑抑郁量表（HAD）评分、匹茨堡睡眠质量指数量表（PSQI）评分及血尿便常规、生化等安全性指标。结果 38例患者完成全部随访,2例发生脱落。PFS、中医证候量表、HAD焦虑量表评分均在试验第4、8、12周显著下降,ECOG评分、HAD抑郁量表均在试验第8、12周显著下降,PSQI评分在治疗第12周显著下降,差异均有统计学意义（P<0.05）。在整个随访过程中,所有患者在治疗后未出现明显血常规、尿便常规及生化指标异常。结论 SGJP可以减轻乳腺癌患者的疲乏,增强体力,改善焦虑抑郁及睡眠质量,值得临床借鉴。

Abstract

关键词

乳腺癌癌因性疲乏疏肝健脾

Keywords

乳腺癌癌因性疲乏疏肝健脾

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