Data mining of medication rule of TCM formulas for PCI post-operation patients by LIU Hong-xu

LI Xuan; CAO Xin-fu; ZHOU Qi; XING Wen-long; TONG Tong; YANG Zhi-hai; LIU Hong-xu

doi:10.16025/j.1674-1307.2020.05.011

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Data mining of medication rule of TCM formulas for PCI post-operation patients by LIU Hong-xu

更新时间：2023-04-11

- Data mining of medication rule of TCM formulas for PCI post-operation patients by LIU Hong-xu
- Beijing Journal of Traditional Chinese Medicine Vol. 39, Issue 5, Pages: 441-445(2020)
- 作者机构：
  
  1. 北京中医药大学
  2. 首都医科大学附属北京中医医院心血管科
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2020.05.011
  CLC：
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[1]李煊,曹新福,周琦,邢文龙,佟彤,杨志海,刘红旭.刘红旭治疗PCI术后患者中医组方用药规律数据挖掘研究[J].北京中医药,2020,39(05):441-445.

LI Xuan, CAO Xin-fu, ZHOU Qi, et al. Data mining of medication rule of TCM formulas for PCI post-operation patients by LIU Hong-xu. [J]. Beijing Journal of Traditional Chinese Medicine 39(5):441-445(2020)
[1]李煊,曹新福,周琦,邢文龙,佟彤,杨志海,刘红旭.刘红旭治疗PCI术后患者中医组方用药规律数据挖掘研究[J].北京中医药,2020,39(05):441-445. DOI： 10.16025/j.1674-1307.2020.05.011.

LI Xuan, CAO Xin-fu, ZHOU Qi, et al. Data mining of medication rule of TCM formulas for PCI post-operation patients by LIU Hong-xu. [J]. Beijing Journal of Traditional Chinese Medicine 39(5):441-445(2020) DOI： 10.16025/j.1674-1307.2020.05.011.

摘要

目的基于数据挖掘探析刘红旭教授治疗经皮冠状动脉介入治疗（percutaneous coronary intervention,PCI）术后患者中医用药特点及组方规律。方法收集2013年1月1日—2018年12月31日期间刘红旭教授在首都医科大学附属北京中医医院门诊诊治的PCI术后患者处方,构建方药数据库。通过频次统计、关联规则分析及系统聚类进行研究。结果共纳入方剂489首,涉及中药162味,出现频率>10%的药物47味;关联规则分析得到关联规则135条;聚类分析得到13个组合。结论刘红旭教授治疗PCI术后患者以多个方剂按照君臣佐使进行组合,善用对药,治疗主证以益气养阴、逐瘀化痰为基本原则,治疗兼证以健脾泻肺、平肝安神为基本原则。

Abstract

Objective To analyze Professor LIU Hong-xu’s TCM medication characteristics and prescription rules for patients after percutaneous coronary intervention（PCI）based on data mining.Methods Collect prescriptions for patient after PCI prescribed by Professor LIU Hong-xu from January 1,2013 to December 31,2018 in the Beijing Hospital of TCM,and establishing a database of TCM formulas.Frequency statistics,association rules analysis,system cluster analysis were conducted.Results There were totally 489 formulas included involving 162 kinds of herbal medicines and 47 kinds with the appearance frequency no less than 10%.There were 135 correlations obtained from association rules analysis and 13 combinations obtained from clustering analysis.Conclusion Professor LIU Hong-xu treats patients after PCI by combining several prescriptions according to monarch drug,minister drug,assistant drug and servant drug; at the same time,he is good at using paired drugs and takes tonifying qi and yin as the major treatment principle,and eliminating stasis and resolving phlegm as the basic principle,accompanied by invigorating the spleen and draining the lung,soothing the liver and tranquilizing the mind.

关键词

刘红旭经皮冠状动脉介入术中医药数据挖掘用药规律

Keywords

LIU Hong-xupercutaneous coronary intervention（PCI）TCMdata miningmedication rule

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