Curative effect of Chaihu plus Longgu Muli Decoction in combination with Duloxetine on fibromyalgia syndrome

CHEN Ai-ping; SHAO Pei-pei; GU Wen; CHEN Peng

doi:10.16025/j.1674-1307.2020.10.015

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Curative effect of Chaihu plus Longgu Muli Decoction in combination with Duloxetine on fibromyalgia syndrome

更新时间：2023-04-11

- Curative effect of Chaihu plus Longgu Muli Decoction in combination with Duloxetine on fibromyalgia syndrome
- Beijing Journal of Traditional Chinese Medicine Vol. 39, Issue 10, Pages: 1067-1070(2020)
- 作者机构：
  
  1. 首都医科大学附属北京中医医院风湿病科
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2020.10.015
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[1]陈爱萍,邵培培,顾文,陈鹏.柴胡加龙骨牡蛎汤联合度洛西汀治疗纤维肌痛综合征60例疗效观察[J].北京中医药,2020,39(10):1067-1070.

CHEN Ai-ping, SHAO Pei-pei, GU Wen, et al. Curative effect of Chaihu plus Longgu Muli Decoction in combination with Duloxetine on fibromyalgia syndrome. [J]. Beijing Journal of Traditional Chinese Medicine 39(10):1067-1070(2020)
[1]陈爱萍,邵培培,顾文,陈鹏.柴胡加龙骨牡蛎汤联合度洛西汀治疗纤维肌痛综合征60例疗效观察[J].北京中医药,2020,39(10):1067-1070. DOI： 10.16025/j.1674-1307.2020.10.015.

CHEN Ai-ping, SHAO Pei-pei, GU Wen, et al. Curative effect of Chaihu plus Longgu Muli Decoction in combination with Duloxetine on fibromyalgia syndrome. [J]. Beijing Journal of Traditional Chinese Medicine 39(10):1067-1070(2020) DOI： 10.16025/j.1674-1307.2020.10.015.

摘要

目的探讨柴胡加龙骨牡蛎汤联合度洛西汀治疗纤维肌痛综合征的临床疗效,并分析其对患者疼痛、情绪、睡眠障碍及疲劳状态的影响。方法采用随机对照法,将纤维肌痛综合征患者120例,随机分为2组,观察组60例,应用柴胡加龙骨牡蛎汤联合度洛西汀治疗;对照组60例,应用度洛西汀治疗。疗程4周,采用疼痛视觉模拟评分（visual analogue scale,VAS）及纤维肌痛症弥漫疼痛指数（widespread pain index,WPI）评估2组患者的疼痛程度及疼痛范围,采用汉密尔顿焦虑量表（Hamilton anxiety scale,HAMA）以及抑郁量表（Hamilton depression scale,HAMD）评估2组患者的情绪变化,采用匹兹堡睡眠指数（Pittsburgh sleep quality index,PSQI）评估2组患者睡眠变化,采用疲劳严重度量表（fatigue severity scale,FSS）评估2组患者疲劳程度,观察2组患者临床疗效及不良反应。结果观察组患者总有效率明显高于对照组（P<0.05）;2组患者的VAS、WPI、HAMD、HAMA、PSQI及FSS均下降且观察组明显优于对照组（P<0.05）;观察组不良反应发生率明显低于对照组。结论柴胡加龙骨牡蛎汤联合度洛西汀治疗纤维肌痛综合征疗效确切且能够改善患者的疼痛、情绪障碍、睡眠障碍及疲劳状态。

Abstract

关键词

柴胡加龙骨牡蛎汤度洛西汀纤维肌痛综合征慢性疼痛情绪障碍

Keywords

柴胡加龙骨牡蛎汤度洛西汀纤维肌痛综合征慢性疼痛情绪障碍

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