DIAO Hua-qiong, TANG Qi-sheng, SHAO Jun, et al. Effect of modified Huanglian Ejiao Decoction on treatment of 42 cases of generalized anxiety disorder in community. [J]. Beijing Journal of Traditional Chinese Medicine 39(12):1225-1228(2020)
DOI:
DIAO Hua-qiong, TANG Qi-sheng, SHAO Jun, et al. Effect of modified Huanglian Ejiao Decoction on treatment of 42 cases of generalized anxiety disorder in community. [J]. Beijing Journal of Traditional Chinese Medicine 39(12):1225-1228(2020) DOI: 10.16025/j.1674-1307.2020.12.001.
Effect of modified Huanglian Ejiao Decoction on treatment of 42 cases of generalized anxiety disorder in community
Objective To investigate the effect of modified Huanglian Ejiao(MHLEJ) Decoction on the treatment of generalized anxiety disorder(GAD)in community. Methods Eighty-four patients with heart-kidney disharmony type of GAD,who visited community health center under the Beijing University of Chinese Medicine and other nearby community health centers from January 2015 to May 2016,were selected and divided into experimental and control groups by using random number table method with forty-two cases each and respectively treated with MHLEJ Decoction and Lorazepam for two weeks. The Hamilton Anxiety Scale(HAMA) and TCM syndrome score were used to compare the results and evaluate the clinical efficacy,and the HAMA rate of score-reducing and efficacy index were used to assess the clinical efficacy before and after treatment of two groups. The follow-up at the third mouth was given after the treatment. Results The differences of scores of HAMA and TCM syndrome between the two groups had no statistical significance after one week of treatment(P>0.05); the difference of HAMA scores between the two groups had statistical significance after two weeks of treatment(P<0.05)and the efficacy of TCM syndrome was remarkably different(P<0.01),and the side effect score was remarkably different(P<0.01).The follow-up results showed that the long-term recurrence rate of the experimental group was lower than that of the control group. Conclusion The MHLEJ Decoction can improve anxiety and TCM symptoms of heart-kidney disharmony type of GAD in community with safety.