Research on the role of test indexes on TCM syndrome differentiation of acute cerebral infarction

ZHANG Peng; WEN Xue; XU Jia; WANG Feng-mei; LIU Wen-juan; LI Qi

doi:10.16025/j.1674-1307.2020.12.023

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Research on the role of test indexes on TCM syndrome differentiation of acute cerebral infarction

更新时间：2023-04-11

- Research on the role of test indexes on TCM syndrome differentiation of acute cerebral infarction
- Beijing Journal of Traditional Chinese Medicine Vol. 39, Issue 12, Pages: 1307-1310(2020)
- 作者机构：
  
  1. 中国中医科学院西苑医院检验科
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2020.12.023
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[1]张鹏,温雪,徐佳,王凤梅,刘文娟,李琦.检验指标对急性脑梗死中医证型鉴别的作用研究[J].北京中医药,2020,39(12):1307-1310.

ZHANG Peng, WEN Xue, XU Jia, et al. Research on the role of test indexes on TCM syndrome differentiation of acute cerebral infarction. [J]. Beijing Journal of Traditional Chinese Medicine 39(12):1307-1310(2020)
[1]张鹏,温雪,徐佳,王凤梅,刘文娟,李琦.检验指标对急性脑梗死中医证型鉴别的作用研究[J].北京中医药,2020,39(12):1307-1310. DOI： 10.16025/j.1674-1307.2020.12.023.

ZHANG Peng, WEN Xue, XU Jia, et al. Research on the role of test indexes on TCM syndrome differentiation of acute cerebral infarction. [J]. Beijing Journal of Traditional Chinese Medicine 39(12):1307-1310(2020) DOI： 10.16025/j.1674-1307.2020.12.023.

摘要

目的观察急性脑梗死（ACI）患者不同中医证型与检验指标差别及规律。方法收集2018年11月—2019年10月在中国中医科学院西苑医院脑病科就诊的ACI患者405例,依照中医辨证分型为风痰阻络组159例、痰浊上扰组81例、阴虚风动组37例、痰瘀阻络组45例、阴虚阳亢组38例和气虚血瘀组45例,分析不同中医证型ACI患者检验指标变化,绘制受试者工作特征（ROC）曲线评价所观察指标对中医证型的鉴别诊断价值。结果痰瘀阻络组PLT水平低于气虚血瘀组、阴虚阳亢组和风痰阻络组（P<0.01）;痰瘀阻络组TCH和Apo-B水平均低于气虚血瘀组（P<0.01）;痰浊上扰组PLT水平低于阴虚阳亢组（P<0.05）;痰浊上扰组UA水平高于气虚血瘀组（P<0.05）;痰浊上扰组Apo-A1水平高于阴虚风动组（P<0.05）。UA在鉴别气虚血瘀组和痰浊上扰组时曲线下面积（AUC）是0.662;PLT在鉴别风痰阻络组和痰瘀阻络组时AUC是0.615;PLT在鉴别气虚血瘀组和痰瘀阻络组时AUC是0.694;PLT在鉴别阴虚阳亢组和痰瘀阻络组时AUC是0.661;Apo-A1在鉴别痰浊上扰组和阴虚风动组时AUC是0.7。结论 PLT、TCH、Apo-B、UA和Apo-A1等指标,可为辨证诊治ACI提供可量化参考。

Abstract

关键词

急性脑梗死中医证型检验指标

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急性脑梗死中医证型检验指标

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