Effect evaluation of Qiju Ganlu Yin triple therapy in treating dry eye related to obstructive meibomian gland dysfunction of lung⁃kidney yin deficiency type
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Effect evaluation of Qiju Ganlu Yin triple therapy in treating dry eye related to obstructive meibomian gland dysfunction of lung⁃kidney yin deficiency type
Beijing Journal of Traditional Chinese MedicineVol. 41, Issue 1, Pages: 7-11(2022)
Cheng⁃yi ZHU, Dong LI, Qiong YI, et al. Effect evaluation of Qiju Ganlu Yin triple therapy in treating dry eye related to obstructive meibomian gland dysfunction of lung⁃kidney yin deficiency type. [J]. Beijing Journal of Traditional Chinese Medicine 41(1):7-11(2022)
DOI:
Cheng⁃yi ZHU, Dong LI, Qiong YI, et al. Effect evaluation of Qiju Ganlu Yin triple therapy in treating dry eye related to obstructive meibomian gland dysfunction of lung⁃kidney yin deficiency type. [J]. Beijing Journal of Traditional Chinese Medicine 41(1):7-11(2022) DOI: 10.16025/j.1674-1307.2022.01.002.
Effect evaluation of Qiju Ganlu Yin triple therapy in treating dry eye related to obstructive meibomian gland dysfunction of lung⁃kidney yin deficiency type
Objective,2,To evaluate the clinical effect of“Qiju Ganlu Yin”in treating mild and moderate dry eyes related to obstructive meibomian gland dysfunction (OMGD)of lung-kidney yin deficiency type.,Methods,2,Using a random number table method,150 patients with mild and moderate dry eyes related to OMGD of lung-kidney yin deficiency type were divided into a control group and a treatment group with 75 cases each.Both groups were treated with 0.1 % pranoprofen,0.1 % sodium hyaluronate eye drops for both eyes and meibomian gland massage.Meanwhile,the treatment group was also given Qiju Ganlu Yin for oral taking and external fumigation,while the control group was fumigated with distilled water.Patients of two groups had 4 weeks of treatment.Then,the overall efficacy,ocular surface disease index(OSDI)score,meibomian gland score,ocular red analysis, fluorescein stain score(FSS),first tear film break-up time(TBUTf),average tear film break-up time(BUTav),lower tear meniscus height(TMH)and TCM syndrome score were observed and analyzed.,Results,2,After treatment,the total effective rate in the treatment group was 90.41 %,which was significantly higher than 65.75 % in the control group(,P,<,0.05).Compared with the control group,OSDI score,the meibomian gland score,eye red analysis,FSS and traditional Chinese medicine(TCM)syndrome score in the treatment group were significantly reduced(,P,<,0.05),while the BUTf,BUTav and TMH in the treatment group were significantly increased(,P,<,0.05).,Conclusion,2,Qiju Ganlu Yin triple therapy can significantly improve the subjective and objective symptoms of mild and moderate dry eye in patients related to OMGD of lung-kidney yin deficiency type,invigorate the lung and the kidney,promote the mutual growth of gold and water,restore the balance of yin and Yang in the lung and kidney,promote the secretion of tear,improve the microcirculation of eye surface,and restore the homeostasis of eye surface.
关键词
阻塞型睑板腺功能障碍干眼杞菊甘露饮金水相生肺肾阴虚型睑板腺按摩熏蒸
Keywords
Obstructive meibomian gland dysfunction OMGDdry eyeQiju Ganlu Yinmutual growth of gold and waterlung-kidney yin deficiency typemeibomian gland massagefumigating treatment
references
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Clinical observation on Qianli Fumigation Recipe combined with meibomian gland massage in treating dry eye related to obstructive meibomian gland dysfunction
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Related Institution
Department of Pharmacy, Beijing No.6 Hospital
Department of Ophthalmology, Beijing Hepingli Hospital
Department of Ophthalmology, Beijing Oriental Hospital,Beijing University of Chinese Medicine