Clinical study on blood pressure regulation of multiple system atrophy by Shengqing Jiangzhuo method

Qian WANG; Chun-yan ZHANG; Yu-jing CHEN; Hong WANG; Ya-nan SUN; Jian-dong WANG; Fei-xue WANG; Xiao-bo HUANG

doi:10.16025/j.1674-1307.2022.07.002

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Clinical study on blood pressure regulation of multiple system atrophy by Shengqing Jiangzhuo method

更新时间：2023-02-15

- Clinical study on blood pressure regulation of multiple system atrophy by Shengqing Jiangzhuo method
- Beijing Journal of Traditional Chinese Medicine Vol. 41, Issue 7, Pages: 709-712(2022)
- 作者机构：
  
  1.首都医科大学宣武医院北京市中西医结合老年疾病研究所，北京 100053
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2022.07.002
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王倩，张春燕，陈玉静，等.升清降浊法对多系统萎缩患者血压调节作用的临床研究［J］.北京中医药，2022，41（7）：709-712.

WANG Qian,ZHANG Chun-yan,CHEN Yu-jing,et al.Clinical study on blood pressure regulation of multiple system atrophy by Shengqing Jiangzhuo method[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(07):709-712.
王倩，张春燕，陈玉静，等.升清降浊法对多系统萎缩患者血压调节作用的临床研究［J］.北京中医药，2022，41（7）：709-712. DOI： 10.16025/j.1674-1307.2022.07.002.

WANG Qian,ZHANG Chun-yan,CHEN Yu-jing,et al.Clinical study on blood pressure regulation of multiple system atrophy by Shengqing Jiangzhuo method[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(07):709-712. DOI： 10.16025/j.1674-1307.2022.07.002.

摘要

目的,2,观察升清降浊法对多系统萎缩（multiple system atrophy，MSA）合并直立性低血压（OH）与仰卧位高血压（SH）患者血压调节作用及相关临床症状的影响。,方法,2,连续纳入2020年6月—2022年10月首都医科大学宣武医院门诊及住院的MSA伴发OH⁃SH患者90例，采用随机数字表法分为观察组和对照组各45例。2组均予盐酸米多君片口服，观察组在此基础上采用升清降浊法组方随症加减治疗。连续治疗8周，观察2组治疗前后直立位、仰卧位血压及卧立位血压差值，直立性低血压自评量表（OHQ）评分、中医证候积分的变化情况。,结果,2,经治疗2组立位收缩压、舒张压均较治疗前升高（,P,<,0.05），且观察组收缩压高于对照组（,P,<,0.05）；2组卧立位收缩压、舒张压差值均较治疗前减低（,P,<,0.05），观察组卧立位收缩压差值低于对照组（,P,<,0.05）。治疗后，2组OHQ量表评分均较治疗前减低（,P,<,0.05），观察组治疗前后评分差值优于对照组（,P,<,0.05）。观察组中医疗效有效率为77.78%，高于对照组的53.33%（,P,<,0.05）。观察组中医证候积分较治疗前减低（,P,<,0.05），对照组差异无统计学意义（,P,>,0.05）。2组均无明显不良反应。,结论,2,升清降浊法对MSA血压异常具有较好的调节作用，可与盐酸米多君协同增效，改善OH且不加重原有SH，并减轻相关临床症状。

Abstract

关键词

升清降浊法多系统萎缩血压调节

Keywords

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