Clinical effect of Huangban Xiaozhong Decoction combined with ranibizumab on qi stagnation and blood stasis type of macular edema due to branch retinal vein occlusion

Cheng-yi ZHU; Dong LI; Qiong YI; Qi-ping WEI

doi:10.16025/j.1674-1307.2022.07.021

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Clinical effect of Huangban Xiaozhong Decoction combined with ranibizumab on qi stagnation and blood stasis type of macular edema due to branch retinal vein occlusion

更新时间：2023-02-15

- Clinical effect of Huangban Xiaozhong Decoction combined with ranibizumab on qi stagnation and blood stasis type of macular edema due to branch retinal vein occlusion
- Beijing Journal of Traditional Chinese Medicine Vol. 41, Issue 7, Pages: 786-790(2022)
- 作者机构：
  
  1.北京市和平里医院眼科，北京100013
  2.北京中医药大学东方医院眼科，北京100078
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2022.07.021
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朱成义，李冬，伊琼，等.黄斑消肿方联合雷珠单抗治疗气滞血瘀型视网膜分支静脉阻塞黄斑水肿的临床疗效［J］.北京中医药，2022，41（7）：786-790.

ZHU Cheng-yi,LI Dong,YI Qiong,et al.Clinical effect of Huangban Xiaozhong Decoction combined with ranibizumab on qi stagnation and blood stasis type of macular edema due to branch retinal vein occlusion[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(07):786-790.
朱成义，李冬，伊琼，等.黄斑消肿方联合雷珠单抗治疗气滞血瘀型视网膜分支静脉阻塞黄斑水肿的临床疗效［J］.北京中医药，2022，41（7）：786-790. DOI： 10.16025/j.1674-1307.2022.07.021.

ZHU Cheng-yi,LI Dong,YI Qiong,et al.Clinical effect of Huangban Xiaozhong Decoction combined with ranibizumab on qi stagnation and blood stasis type of macular edema due to branch retinal vein occlusion[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(07):786-790. DOI： 10.16025/j.1674-1307.2022.07.021.

摘要

目的,2,观察黄斑消肿方联合雷珠单抗治疗气滞血瘀型视网膜分支静脉阻塞黄斑水肿的临床效果。,方法,2,采用随机数字表的方法将62例（62只眼）气滞血瘀型视网膜分支静脉阻塞黄斑的患者分为对照组和观察组各31例（31只眼）。2组均给予玻璃体腔注射（IRI）雷珠单抗，注射次数为3次+必要时（PRN）。观察组在对照组治疗基础上，给予黄斑消肿方。2组研究周期为12个月。观察并对比2组疗效、中医证候总分、最佳矫正视力（BCVA）、黄斑中心区视网膜厚度（CST）、IRI注射次数及PRN间隔时间。,结果,2,治疗后，观察组总有效率高于对照组（,P,<,0.05）。治疗后1、6、12个月观察组中医证候总分、各症状积分、CST低于对照组（,P,<,0.05），BCVA高于对照组（,P,<,0.05）。观察组平均IRI注射次数是3（3，4）次，对照组平均IRI注射次数是5（4，6）次，2组平均IRI注射次数及PRN间隔时间比较差异有统计学意义（,P,<,0.05）。,结论,2,黄斑消肿方联合雷珠单抗治疗气滞血瘀型视网膜分支静脉阻塞黄斑水肿的临床效果优于单纯雷珠单抗治疗，可显著改善患者的中医证候，降低CST，提高BCVA，减少IRI注射次数，延长PRN间隔时间。

Abstract

关键词

黄斑消肿方雷珠单抗视网膜分支静脉阻塞黄斑水肿气滞血瘀型

Keywords

references

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