Clinical observation on Qianli Fumigation Recipe combined with meibomian gland massage in treating dry eye related to obstructive meibomian gland dysfunction

Hai-juan MA; Cheng-yi ZHU; Qi-ping WEI

doi:10.16025/j.1674-1307.2022.08.023

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Clinical observation on Qianli Fumigation Recipe combined with meibomian gland massage in treating dry eye related to obstructive meibomian gland dysfunction

更新时间：2023-02-15

- Clinical observation on Qianli Fumigation Recipe combined with meibomian gland massage in treating dry eye related to obstructive meibomian gland dysfunction
- Beijing Journal of Traditional Chinese Medicine Vol. 41, Issue 8, Pages: 912-916(2022)
- 作者机构：
  
  1.北京市第六医院药剂科，北京 100007
  2.北京市和平里医院眼科，北京100013
  3.北京中医药大学东方医院眼科，北京 100078
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2022.08.023
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马海娟，朱成义，韦企平.千里熏蒸方联合睑板腺按摩治疗阻塞型睑板腺功能障碍相关干眼的临床观察［J］.北京中医药，2022，41（8）：912-916.

MA Hai-juan,ZHU Cheng-yi,WEI Qi-ping.Clinical observation on Qianli Fumigation Recipe combined with meibomian gland massage in treating dry eye related to obstructive meibomian gland dysfunction[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(08):912-916.
马海娟，朱成义，韦企平.千里熏蒸方联合睑板腺按摩治疗阻塞型睑板腺功能障碍相关干眼的临床观察［J］.北京中医药，2022，41（8）：912-916. DOI： 10.16025/j.1674-1307.2022.08.023.

MA Hai-juan,ZHU Cheng-yi,WEI Qi-ping.Clinical observation on Qianli Fumigation Recipe combined with meibomian gland massage in treating dry eye related to obstructive meibomian gland dysfunction[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(08):912-916. DOI： 10.16025/j.1674-1307.2022.08.023.

摘要

目的,2,观察千里熏蒸方联合睑板腺按摩治疗阻塞型睑板腺功能障碍相关干眼的临床效果。,方法,2,采用随机数字表法，将150例轻中度阻塞型睑板腺功能障碍相关干眼的患者分为对照组和治疗组。2组均采用0.1%普拉洛芬滴眼液、0.1%玻璃酸钠滴眼液和睑板腺按摩治疗。同时治疗组采用千里熏蒸方熏蒸治疗，而对照组采用蒸馏水熏蒸治疗。2组疗程均为1个月。1个月后，观察2组的总有效率、眼表疾病指数（OSDI）评分、睑板腺评分、眼红分析、荧光素钠染色评分（FSS）、首次非侵入性泪膜破裂时间（NIBUTf）、平均非侵入性泪膜破裂时间（NIBUTav）、泪河高度（TMH）的变化情况。,结果,2,治疗后，治疗组的总有效率为91.79%，高于对照组的65.75%（,P,<,0.05）；与对照组比较，治疗组的OSDI评分、睑板腺评分、眼红分析、FSS均降低，NIBUTf、NIBUTav、TMH均提高（,P,<,0.05）。,结论,2,千里熏蒸方联合睑板腺按摩可有效缓解阻塞型睑板腺功能障碍相关干眼患者的主客观症状，增加泪液分泌量，延长泪膜破裂时间，恢复泪膜稳态，改善眼表微环境，恢复睑板腺对睑酯的正常调控。

Abstract

Objective,2,To observe the clinical effect of Qianli Fumigation Recipe combined with meibomian gland massage in the treatment of dry eye （DE） related to obstructive meibomian gland dysfunction （OMGD）.,Methods,2,Using random number table method，150 patients with mild to moderate dry eye related to OMGD were divided into a control group and a treatment group of 75 cases each. Both groups were treated with 0.1% pranoprofen， 0.1% sodium hyaluronate eye drops and meibomian gland massage. Meanwhile，the treatment group was also treated with fumigation by Qianli Fumigation Recipe，while the control group was treated with distilled water fumigation. Two groups of patients received one month of treatment as one course. Later，the overall efficacy and changes of OSDI score，BUTf，BUTav，TMH，meibomian gland score，eye red analysis and FSS of two groups were measured and evaluated.,Results,2,After treatment，the total effective rate of the treatment group was 91.79%，which was significantly higher than 65.75% of the control group（,P,<,0.05）. Compared with the control group，OSDI score， meibomian gland score，eye red analysis and FSS of the treatment group were significantly reduced. BUTf，BUTav and TMH of the treatment group were significantly increased（,P,<,0.05）.,Conclusion,2,Qianli Fumigation Recipe combined with meibomian gland massage can effectively alleviate the subjective and objective symptoms of DE related to OMGD，increase the secretion of tear fluid，prolong tear film rupture time，restore tear film stability，improve ocular surface microscopy environment，and restore the normal regulation of meibomian glands on meibomian esters.

关键词

阻塞型睑板腺功能障碍相关干眼千里熏蒸方睑板腺按摩

Keywords

Dry eye related to OMGDQianli Fumigation Recipemeibomian gland massage

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