Objective,2,To observe the curative effect of Qing's palace bone setting manipulation of pulling， poking， rubbing and twisting methods（QPM） in the treatment of lateral epicondylitis（LE） on the basis of the theory of combining dynamic with static and taking activity as the dominant factor.,Methods,2,A total of 64 patients with LE who received treatment in Wangjing Hospital of China Academy of Chinese Medical Sciences from October 2020 to December 2021 were selected and randomly divided into manipulation group and control group with 32 cases in each group. Both two groups shad got related education and elbow exercise guidence. The manipulation group were treated with the QPM method 3 times a week for 4 weeks；and the control group was applied with Diclofenac Diethylamine Emulgel and wore elbow padsonce a dayfor 4 weeks. The visual analogue scale（VAS） score， the hospital for special surgery（HSS） elbow joint score and the elbow tenderness threshold of two groups were obtained before treatment， immediately and 2 months after complete treatment so as to compare the clinical efficacy between two groups.,Results,2,The VAS score， HSS score， and elbow tenderness threshold of immediately and 2 months after complete treatment in two groups were significantly improved than before treatment（,P,<,0.05）. Significant improvements were observed in VAS score， HSS score and tenderness threshold immediately and 2 months after complete treatment in the manipulation group compared with the control group （,P,<,0.05）. Compared with instant after complete treatment， there was no significant difference in the VAS score of 2 months after complete treatment in the manipulation group（,P,>,0.05）， but the VAS score of 2 months after complete treatment in the control group was significantly was increased，the HSS score and the tenderness threshold were significantly decreased（,P,<,0.05） and the HSS score and the tenderness threshold were significantly decreased（,P,<,0.05）.,Conclusion,2,Based on the theory of combining dynamic with static and taking activity as the dominant factor， QPM method has a good clinical effect oneasing the pain and improving function of elbow joint than applying nonsteroidal antiinflammatory drugs （NSAIDs）externally.