GUO Jing-zhuo,DU Zhi-xin,XU Xu-ying.Study on correlation between TCM syndrome types and test indicators in patients with diabetic foot[J]. Beijing Journal of Traditional Chinese Medicine,2023,42(06):685-688.
GUO Jing-zhuo,DU Zhi-xin,XU Xu-ying.Study on correlation between TCM syndrome types and test indicators in patients with diabetic foot[J]. Beijing Journal of Traditional Chinese Medicine,2023,42(06):685-688. DOI: 10.16025/j.1674-1307.2023.06.025.
Study on correlation between TCM syndrome types and test indicators in patients with diabetic foot
Objective,2,To analyze the correlation between TCM syndrome types and test indicators in patients with diabetic foot (DF),.,Methods,2,The medical records of 177 DF inpatients in the Department of Ulcer Vascular Surgery, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University hospitalized from January 2019 to December 2021 were collected and retrospectively analyzed,and the correlation between each syndrome type and test index was analyzed by Spearman correlation.,Results,2,Among the 177 patients, 86 cases (48.6%) had Qi deficiency and blood stasis syndrome, 54 cases (30.5%) had excessive damp-heat syndrome, 37 cases of deficiency of both Qi and Yin, accounting for 20.9%. There was no significant difference in age, sex and the proportion of peripheral vascular disease (PAD), peripheral neuropathy (DFN), diabetic nephropathy (DR) and diabetic retinopathy (DN) among the patients of each syndrome type (,P,>,0.05). There was significant difference in the disease course of type 2 diabetes in patients with different syndromes (,P,<,0.05), and the course of type 2 diabetes in patients with Qi deficiency and blood stasis syndrome was shorter than that in patients with deficiency of both Qi and Yin (,P,<,0.05). There were significant differences in ACE among patients with different syndromes (,P,<,0.05), and the excess of damp-heat syndrome ,<, Qi deficiency and blood stasis syndrome ,<, deficiency of both Qi and Yin, and the ACE of patients with excess of damp-heat syndrome was lower than that of patients with deficiency of both Qi and Yin, with statistical significance (,P,<,0.05). There was no significant difference in LDH-L, CK, CKMB, ALP, BNP, ALT, AST, GGT, TBIL, Cr, UA and UREA among the syndromes (,P,>,0.05). Syndrome types were positively correlated with CK, ACE, Cr and UA (r were 0.155, 0.206, 0.166 and 0.152, respectively, ,P,<,0.05),.,Conclusion,2,Among DF TCM syndromes,Qi deficiency and blood stasis syndrome is the most common. Patients with excessive dampness and heat syndrome have the lowest ACE level,while patients with deficiency of Qi and Yin syndrome have the highest Cr level.
关键词
糖尿病足肌酐血管紧张素转化酶中医证型
Keywords
Diabetic footcreatinineangiotensin converting enzymeTCM syndrome type
references
SUN H, SAEEDI P, KARURANGA S, et al. IDF diabetes atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045[J]. Diabetes Res Clin Pract,2022,183:109119.