Analysis of medication rules of patent Chinese herbal medicines for the treatment of ulcerative colitis in Chinese Pharmacopoeia based on data mining

LIU Jun-cen; BA Yin-ying; WANG Wen-juan; WANG Jia-jia

doi:10.16025/j.1674-1307.2023.07.028

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Analysis of medication rules of patent Chinese herbal medicines for the treatment of ulcerative colitis in Chinese Pharmacopoeia based on data mining

更新时间：2023-08-24

- Analysis of medication rules of patent Chinese herbal medicines for the treatment of ulcerative colitis in Chinese Pharmacopoeia based on data mining
- Beijing Journal of Traditional Chinese Medicine Vol. 42, Issue 7, Pages: 808-812(2023)
- 作者机构：
  
  1.首都医科大学中医药学院，北京 100069
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2023.07.028
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刘俊岑，巴寅颖，王文娟，等.基于数据挖掘方法分析《中华人民共和国药典》中治疗溃疡性结肠炎的中成药用药规律［J］.北京中医药，2023，42（7）：808-812.

LIU Jun-cen,BA Yin-ying,WANG Wen-juan,et al.Analysis of medication rules of patent Chinese herbal medicines for the treatment of ulcerative colitis in Chinese Pharmacopoeia based on data mining[J]. Beijing Journal of Traditional Chinese Medicine,2023,42(07):808-812.
刘俊岑，巴寅颖，王文娟，等.基于数据挖掘方法分析《中华人民共和国药典》中治疗溃疡性结肠炎的中成药用药规律［J］.北京中医药，2023，42（7）：808-812. DOI： 10.16025/j.1674-1307.2023.07.028.

LIU Jun-cen,BA Yin-ying,WANG Wen-juan,et al.Analysis of medication rules of patent Chinese herbal medicines for the treatment of ulcerative colitis in Chinese Pharmacopoeia based on data mining[J]. Beijing Journal of Traditional Chinese Medicine,2023,42(07):808-812. DOI： 10.16025/j.1674-1307.2023.07.028.

摘要

目的,2,运用古今医案云平台与名医传承辅助平台的数据挖掘方法分析2020版《中华人民共和国药典》（简称《药典》）中治疗溃疡性结肠炎（UC）的成方制剂和单味制剂的用药规律与组方特点。,方法,2,对2020版《药典》所载的治疗UC的方剂进行筛选，将所选成方和单味制剂的药物组成、功效主治等录入Excel 2007软件，数据标准化后导入平台，对症状和药物进行标准化标注后进行数据分析与挖掘。,结果,2,《药典》中治疗UC的成方制剂和单味制剂共计106种，涉及UC相关症状99个，中药237味，核心药物为木香、茯苓、陈皮、甘草等22味，药物功效主要为清热解毒、行气止痛、燥湿化痰、清热燥湿等，药物归经以脾、胃经为主，药物四气多为温性、平性、寒性，五味多为辛味、苦味、甘味，潜在药物组合包括当归-黄芪、白术-党参、黄连-黄芩等95对，潜在药物群共10类。UC的核心症状有腹泻、腹痛、恶心、呕吐、腹胀、大便脓血等，存在以茯苓、陈皮、白术等治疗腹痛，苍术、黄连、广藿香等治疗腹泻等药症关联规律。,结论,2,《药典》中治疗UC的中成药组方中多为味辛性温之品，归脾、胃经，具有清热、解毒、燥湿、健脾等作用，药物组合体现了辨证治疗中消食药、补益药、安神药、理气药等诸种药物的合理应用。

Abstract

关键词

溃疡性结肠炎中成药数据挖掘用药规律

Keywords

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