Objective,2,To analyze the therapeutic effect of Sangbaipi Decoction on bronchiectasis with phlegm-heat obstructing the lung syndrome.,Methods,2,A total of 62 patients with bronchiectasis with phlegm-heat obstructing the lung syndrome， who visited Longhua Hospital Affiliated to the Shanghai University of Traditional Chinese Medicine from January 2019 to December 2022， were randomly divided into a traditional Chinese medicine （TCM） group（,n,=31） and a control group（,n,=31）. The control group received routine western medicine treatment alone， and the TCM，group received western medicine combined with Sangbaipi Decoction Granules for one month. The proportion of acute exacerbation of bronchiectasis within 3 months after treatment， the pulmonary function indicators before and after treatment， and the St. George's Respiratory Questionnaire （SGRQ） before and after treatment were compared between the two groups， and the adverse events and laboratory indicators were recorded simultaneously.,Results,2,Within 3 months after treatment， there were 4 cases of acute exacerbation in TCM group and 5 cases in control group， with no statistical significance（,P,>,0.05）. At the end of 3 months after treatment， the SGRQ scores （symptoms， activity， psychological score and total score） in both groups were lower than those before treatment（,P,<,0.05）， and the SGRQ scores in TCM group were higher than those in the control group（,P,<,0.05）.At the end of 3 months after treatment， the pulmonary function parameters （FEV1，FVC，FEV1/FVC） of the two groups were all improved compared with those before treatment， but there was no statistical difference between the two groups（,P,>, 0.05）. Compared with the control group， there was no significant difference in the improvement of pulmonary function indexes in the Chinese medicine group（,P,>,0.05）. The incidence of adverse events in TCM group was 32.3%（10/31）， including 4 cases of diarrhea， 3 cases of abdominal distension and 3 cases of nausea. The incidence of adverse events in the control group was 35.5%（11/31）， including 5 cases of diarrhea， 2 cases of abdominal distension and 4 cases of nausea. There was no significant difference between the two groups （,χ,2,=0.072，,P,>,0.05）.,Conclusion,2,Conventional western medicine treatment combined with Sangbaipi Decoction can significantly improve the clinical symptoms， activity/endurance， and psychological state inpatients with bronchiectasis of phlegm-heat obstructing the lung syndromewith good safety.