Objective,2,To explore the clinical efficacy of acupoint catgut embedding combined with oral administration of traditional Chinese medicine in the treatment of slow transit constipation of qi deficiency type under the guidance of theory of Three Jiao Viscera.,Methods,2,A total of 63 outpatients admitted to the Beijing Anorectal Hospital（Beijing Erlong Road Hospital）from June 2022 to September 2022 were collected and randomly divided into a control group and an observation group using random number table method. The observation group was treated with acupoint catgut embedding combined with oral administration of traditional Chinese medicine， while the control group was treated with polyethylene glycol 4 000 powder with 10 g/time and 2 times/d combined with mosapride citrate with 5 mg/time and 3 Times/d. Both groups were treated for 8 weeks. Comparative analysis was conducted on chronic constipation severity rating scale（CSS）， colonic transit test results， serum NO，Ach， gastrointestinal hormone expression levels SP，MTL and GAS of patients before and after 8 weeks of treatment. The overall effective rate and quality of life （PAC-QOL self-assessment scale） scores of patients with constipation were compared after treatment .,Results,2,The total effective rate of the observation group was 90. 62%， which was higher than that of the control group 64. 52%（,P,<,0.05）. After 8 weeks of treatment， the frequency of defecation， defecation effort， time to go to the toilet every time， times of unsuccessful defecation and scores of incomplete defecation in the two groups were all lower than those before treatment（,P,<,0.05）， and the scores in the observation group were lower than those in the control group（,P,<,0.05）， and the amount of markers in the observation group was higher than that in the control group（,P,<,0.05）， and the serum levels of Ach， GAS， SP and MTL in the observation group were lower than those in the control group， while the serum levels of Ach， GAS， SP and MTL in the observation group were higher than those in the control group（,P,<,0.05）.The quality of life scores of the two groups were higher than before treatment（,P,<,0.05），and the quality of life scores of the observation group were higher than those of the control group（,P,<,0.05）.,Conclusion,2,Acupoint catgut embedding combined with oral administration of traditional Chinese medicine under the guidance of the Three Jiao Viscera theory can significantly alleviate the symptoms of constipation，increase clinical efficacy，and improve the quality of life of STC type of patients with Qi deficiency.