BAI Zhiyuan,WANG Wei,JIANG Wenjiao,et al.Efficacy of subcutaneous embedding acupuncture therapy on chemotherapy-induced nausea and vomiting in children with soft tissue sarcoma[J]. Beijing Journal of Traditional Chinese Medicine,2024,43(03):261-264.
BAI Zhiyuan,WANG Wei,JIANG Wenjiao,et al.Efficacy of subcutaneous embedding acupuncture therapy on chemotherapy-induced nausea and vomiting in children with soft tissue sarcoma[J]. Beijing Journal of Traditional Chinese Medicine,2024,43(03):261-264. DOI: 10.16025/j.1674-1307.2024.03.007.
Efficacy of subcutaneous embedding acupuncture therapy on chemotherapy-induced nausea and vomiting in children with soft tissue sarcoma
摘要
目的
2
观察揿针疗法防治软组织肉瘤(soft tissue sarcoma, STS)患儿化疗所致恶心呕吐(chemotherapy-induced nausea and vomting, CINV)的效果。
方法
2
选取2021年5月—2022年5月首都医科大学附属北京儿童医院肿瘤内科病房收治的STS患儿74例,按照随机数字表法将患儿分为试验组和对照组各37例。2组均接受长春新碱+阿霉素+环磷酰胺(vincristine+ doxorubicin+ cyclophosphamide, VDC)方案化疗,试验组在上述化疗基础上加揿针治疗。对比2组化疗第1、2天CINV发生情况和生活功能指数量表(functional living index-emesis, FLIE)评分。
结果
2
与对照组比较,试验组化疗第1、2天恶心、呕吐严重程度更低(
P
<
0.05),化疗期间FLIE评分高(
P
<
0.05)。
结论
2
揿针疗法可减少STS患儿化疗所致CINV的发生,提高患儿化疗期间的生活质量。
Abstract
Objective
2
To explore the efficacy of subcutaneous embedding acupuncture therapy on chemotherapy-induced nausea and vomiting in children with soft tissue sarcoma(STS).
Methods
2
74 children with STS who were admitted into the Oncology ward of our hospital from May 2021 to May 2022 were selected and were divided into control group and experimental group by random number table. All children underwent vincristine+ doxorubicin+ cyclophosphamide (VDC) treatment. The control group (37 cases) was treated with routine western medicine ondansetron hydrochloride injection with intravenous injection for antiemetic treatment. The experimental group (37 cases) was treated with external treatment of traditional Chinese medicine for subcutaneous embedding acupuncture therapy on the basis of western medicine antiemetic treatment in the control group. The chemotherapy-induced nausea and vomting(CINV) on day 1 and day 2 and functional living index-emesis(FLIE) of 2 groups before and after intervention were collected and compared.
Results
2
Compared with the control group, the severity of nausea, vomiting in the experimental group on chemotherapy d1 and d2 were significantly reduced (
P
<
0.05). Compared with the control group, the FLIE of the experimental group during chemotherapy was significantly higher(
P
<
0.05).
Conclusion
2
Subcutaneous embedding acupuncture therapy can significantly reduce the occurrence of CINV and improve FLIE in children with soft tissue sarcoma.
关键词
软组织肉瘤儿童揿针化疗恶心呕吐
Keywords
Soft tissue sarcomachildrensubcutaneous embedding acupuncturechemotherapynausea and vomiting
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TOTADRI S. Prophylaxis and management of antineoplastic drug in-duced nausea and vomiting in children with cancer[J]. J Pediatr Hematol Oncol, 2016,1(3):50-55.
MARTIN AR, PEARSON JD, CAI B, et al. Assessing the impact of chemotherapy-induced nausea and vomiting on patients' daily lives: a modified version of the Functional Living Index-Emesis (FLIE) with 5-day recall[J]. Support Care Cancer, 2003,11(8):522-527.
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Related Institution
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