MA JIANXIONG, YE MIAOYONG, LI HAISONG, et al. Pathogenesis and therapeutic methods of diabetic erectile dysfunction based on collateral disease theory. [J]. Beijing journal of traditional chinese medicine, 2025, 44(1): 23-27.
DOI:
MA JIANXIONG, YE MIAOYONG, LI HAISONG, et al. Pathogenesis and therapeutic methods of diabetic erectile dysfunction based on collateral disease theory. [J]. Beijing journal of traditional chinese medicine, 2025, 44(1): 23-27. DOI: 10.16025/j.1674-1307.2025.01.005.
Pathogenesis and therapeutic methods of diabetic erectile dysfunction based on collateral disease theory
Diabetic erectile dysfunction (ED) is one of the common complications of diabetes and is classified as refractory erectile dysfunction (RED), for which clinical treatment strategies still need to be explored. Based on the "collateral disease theory" and the unique anatomical structure of the penile corpus cavernosum, it was proposed that RED, including diabetic ED, should be classified as "penis collateral disease". From this perspective, the pathogenesis and treatment methods of diabetic ED were discussed through a trinity approach, considering disease location, etiology, and pathology. The "penile collateral vessels" represent the micro-location of diabetic ED. The "internal heat" condition is a specific cause of the onset and progression of diabetic ED, and micro-lumps in the penile collateral vessels are the key pathological changes in diabetic ED. Treatment should focus on replenishing qi and activating blood, dredging collaterals, dispelling micro-lumps, and clearing the internal heat pathogen.
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