Connotation of TCM prevention and treatment of type 2 diabetes mellitus panangiopathy based on the theory of "latent evil blocking collaterals"

LI Jie; ZHENG Yafeng; ZHUANG Xin; XU Yunsheng

doi:10.16025/j.1674-1307.2025.01.024

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Connotation of TCM prevention and treatment of type 2 diabetes mellitus panangiopathy based on the theory of "latent evil blocking collaterals"

更新时间：2025-01-24

- Connotation of TCM prevention and treatment of type 2 diabetes mellitus panangiopathy based on the theory of "latent evil blocking collaterals"
- Beijing Journal of Traditional Chinese Medicine Vol. 44, Issue 1, Pages: 114-117(2025)
- 作者机构：
  
  1.山东中医药大学科研处，济南 250014
  2.山东中医药大学第二附属医院治未病中心，济南 250001
  3.山东中医药大学附属医院心内科，济南 250014
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2025.01.024
  CLC：
- Published：25 January 2025，
  
  Received：01 December 2023，
- 稿件说明：
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LI JIE, ZHENG YAFENG, ZHUANG XIN, et al. Connotation of TCM prevention and treatment of type 2 diabetes mellitus panangiopathy based on the theory of "latent evil blocking collaterals". [J]. Beijing journal of traditional chinese medicine, 2025, 44(1): 114-117.
DOI：

LI JIE, ZHENG YAFENG, ZHUANG XIN, et al. Connotation of TCM prevention and treatment of type 2 diabetes mellitus panangiopathy based on the theory of "latent evil blocking collaterals". [J]. Beijing journal of traditional chinese medicine, 2025, 44(1): 114-117. DOI： 10.16025/j.1674-1307.2025.01.024.

摘要

2型糖尿病（T2DM）泛血管病变是指T2DM患者广泛血管（涵盖心、脑、眼、肾、外周等大血管和微血管）出现以动脉粥样硬化为共同病理特征，以心脑血管事件为主要结局的一种临床综合征。有效阻止血管高糖“代谢记忆”是目前T2DM泛血管病变临床防治的核心。中医“伏邪”是指伏藏于体内、不立即发作的病邪（包括糖浊、糖瘀、糖毒、脂浊等），易藏匿于络脉，参与T2DM泛血管病变的发生发展，导致高糖“代谢记忆”，损伤血管内皮，加重病情。在“伏邪阻络”理论指导下，深入探究中医药防治T2DM泛血管病变具有重要意义，可为拓宽临床诊治思路提供借鉴。

Abstract

Type 2 diabetes mellitus （T2DM） panangiopathy refers to a clinical syndrome in T2DM patients characterized by widespread vascular involvement， including large blood vessels （such as the heart， brain， eyes， kidneys， and peripheral vessels） as well as microvessels. Atherosclerosis is the common pathological feature， and cardiovascular and cerebrovascular events are the primary outcomes. Effectively preventing vascular hyperglycemia and its "metabolic memory" is the core of current clinical prevention and treatment for T2DM panangiopathy. In traditional Chinese medicine （TCM）， "latent evil" refers to pathogenic factors hidden within the body that do not immediately cause disease （including sugar turbidity， sugar stasis， sugar toxins， and fat turbidity）. These factors tend to hide in the collateral vessels and are involved in the onset and progression of T2DM panangiopathy， leading to high blood sugar "metabolic memory"， which damages the vascular endothelium and exacerbates the condition. Under the guidance of the theory of "latent evil blocking collaterals”， exploring the role of TCM in the prevention and treatment of T2DM panangiopathy is of great significance， offering valuable insights for expanding clinical diagnosis and treatment strategies.

关键词

2型糖尿病泛血管病变中医药伏邪阻络代谢记忆

Keywords

Type 2 diabetes mellituspanangiopathytraditional Chinese medicinelatent evil blocking collateralsmetabolic memory

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