ZHANG Nannan,RAO Xiangrong.RAO Xiangrong's experience in diagnosis and treatment of idiopathic membranous nephropathy complicated with acute kidney injury[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(06):751-753.
ZHANG Nannan,RAO Xiangrong.RAO Xiangrong's experience in diagnosis and treatment of idiopathic membranous nephropathy complicated with acute kidney injury[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(06):751-753. DOI: 10.16025/j.1674-1307.2025.06.017.
RAO Xiangrong's experience in diagnosis and treatment of idiopathic membranous nephropathy complicated with acute kidney injury
The pathogenesis of idiopathic membranous nephropathy (IMN) complicated with acute kidney injury (AKI) is complex and involves multiple factors. Based on clinical experience, professor RAO Xiangrong believes that the pathogenesis of IMN complicated with AKI is characterized by deficiency of the root and excess of the manifestation, spleen and kidney insufficiency, and obstruction caused by dampness and blood stasis. Treatment should first differentiate the severity of lesions in the triple energizerand adopt the principles of treating the upper energizer with dredging, harmonizing the middle energizer, and directing the lower energizer downward. Tonifying deficiency, activating blood circulation, and promoting diuresis should be applied throughout the treatment, with frequent emphasis on reconciliation and maintaining balance. It is important to distinguish the severity and urgency during treatment. Integrating traditional Chinese and western medicine can improve clinical efficacy and reduce the occurrence of clinical endpoint events.
关键词
Keywords
references
CATTRAN DC , BRENCHLEY PE . Membranous nephropathy: integrating basic science into improved clinical management [J ] . Kidney Int , 2017 , 91 ( 3 ): 566 - 574 .
XU X , WANG G , CHEN N , et al . Long-term exposure to air pollution and increased risk of membranous nephropathy in China [J ] . J Am Soc Nephrol , 2016 , 27 ( 12 ): 3739 - 3746 .
LI Z , WENG M , LIN L , et al . Acute kidney injury in patients with idiopathic membranous nephropathy: influencing factors and prognosis [J ] . Ren Fail , 2023 , 45 ( 1 ): 2194451 .
CHEN T , ZHOU Y , CHEN X , et al . Acute kidney injury in idiopathic membranous nephropathy with nephrotic syndrome [J ] . Ren Fail , 2021 , 43 ( 1 ): 1004 - 1011 .
ZHOU XM , CHEN QH . Biochemical study of Chinese rhubarb.XXII.inhibitory effect of anthraquinone derivatives on Na + -K + -ATPase of the rabbit renal medulla and their diuretic action [J ] . Yaoxue Xuebao , 1988 , 23 ( 1 ): 17 - 20 .