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1.北京中医药大学东方医院耳鼻喉科,北京 100078
2.北京中医药大学东直门医院耳鼻喉科,北京 100700
Received:22 July 2024,
Published:25 August 2025
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高天凤,吴文丽,刘大新,等.疏肝止眩饮治疗原发性后半规管良性阵发性位置性眩晕复位后残余头晕(肝郁脾虚证)疗效观察[J].北京中医药,2025,44(8):992-996.
GAO Tianfeng,WU Wenli,LIU Daxin,et al.Clinical efficacy of Shugan Zhixuan Decoction in the treatment of residual dizziness (liver depression and spleen deficiency syndrome) of primary posterior semicircular canal BPPV after reposition[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(08):992-996.
高天凤,吴文丽,刘大新,等.疏肝止眩饮治疗原发性后半规管良性阵发性位置性眩晕复位后残余头晕(肝郁脾虚证)疗效观察[J].北京中医药,2025,44(8):992-996. DOI: 10.16025/j.1674-1307.2025.08.009.
GAO Tianfeng,WU Wenli,LIU Daxin,et al.Clinical efficacy of Shugan Zhixuan Decoction in the treatment of residual dizziness (liver depression and spleen deficiency syndrome) of primary posterior semicircular canal BPPV after reposition[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(08):992-996. DOI: 10.16025/j.1674-1307.2025.08.009.
目的
2
观察疏肝止眩饮治疗原发性后半规管良性阵发性位置性眩晕(BPPV)复位后残余头晕(肝郁脾虚证)的疗效。
方法
2
选择2022年6月—2023年3月于北京中医药大学东方医院耳鼻喉科前庭中心确诊的原发性后半规管BPPV患者,经复位后残余头晕(RD)肝郁脾虚证患者80例。用随机数字表法将患者分为观察组、对照组。观察组给予疏肝止眩饮颗粒制剂,对照组给予疏肝止眩饮模拟安慰剂,2组均用50~100 mL温开水冲服,1袋/次,2次/d,连续用药14 d。对比2组治疗前后眩晕中医证候量表积分、疗效;记录改良感觉整合和平衡临床试验(mCTSIB)4种不同静态站姿下[睁眼硬底(Firm-EO)、闭眼硬底(Firm-EC)、睁眼软底(Foam-EO)、闭眼软底(Foam-EC)]的晃动速度;比较眩晕残障程度量表(DHI)评分。
结果
2
治疗后,2组眩晕中医证候量表积分均较治疗前下降(
P
<
0.05),且观察组眩晕中医证候量表积分低于对照组(
P
<
0.05)。观察组总有效率为91.67%,高于对照组总有效率73.68%(
P
<
0.05)。治疗后,2组Foam-EO、Foam-EC站立条件下的晃动速度均较治疗前下降(
P
<
0.05),且观察组Foam-EO、Foam-EC站立条件下的晃动速度低于对照组(
P
<
0.05)。治疗后,2组DHI评分较治疗前下降(
P
<
0.05),且观察组DHI评分均低于对照组(
P
<
0.05)。
结论
2
疏肝止眩饮能有效改善原发性后半规管BPPV复位后残余头晕症状,疗效显著。
Objective
2
To
observe the efficacy of
Shugan Zhixuan
Decoction
in treating residual dizziness (liver depression and spleen deficiency syndrome) after reposition in patients with primary posterior semicircular canal benign paroxysmal positional vertigo (BPPV).
Methods
2
A total of 80 patients with primary posterior semicircular canal BPPV and residual dizziness (liver depression and spleen deficiency syndrome) who were diagnosed at the Vestibular Center, Department of Otorhinolaryngology, Dongfang Hospital, Beijing University of Chinese Medicine from June 2022 to March 2023 were selected. These patients were randomly divided into the observation group and the control group using a random number table. The observation group received
Shugan Zhixuan
Decoction
granules, while the control group received a placebo simulating
Shugan Zhixuan
Decoction
. Both groups were administered 1 packet per dose, twice a day, dissolved in 50–100 mL of warm water, for 14 consecutive days. Before and after treatment, the traditional Chinese medicine (TCM) dizziness syndrome scale score and therapeutic effect were compared between the two groups. Additionally, the Modified Clinical Test of Sensory Interaction on Balance (mCTSIB) was used to measure static postural sway under four conditions [eyes open on firm surface (Firm-EO), eyes closed on firm surface (Firm-EC), eyes open on foam surface (Foam-EO), and eyes closed on foam surface (Foam-EC)]. The swaying velocity was compared. The Dizziness Handicap Inventory (DHI) scores were also compared.
Results
2
After treatment, both groups showed a significant decrease in TCM dizziness syndrome scale scores compared to baseline (
P
<
0.05). The observation group had lower TCM dizziness syndrome scale scores than the control group (
P
<
0.05). The total effective rate in the observation group was 91.67%, significantly
higher than 73.68% in the control group (
P
<
0.05). After treatment, the sway velocity under Foam-EO and Foam-EC conditions decreased in both groups compared to baseline (
P
<
0.05), with the observation group showing a lower sway velocity than the control group (
P
<
0.05). The DHI scores for both groups decreased significantly after treatment (
P
<
0.05), with the observation group having lower DHI scores than the control group (
P
<
0.05).
Conclusion
2
Shugan Zhixuan
Decoction
can effectively improve residual dizziness symptoms after reposition in primary posterior semicircular canal BPPV, with significant therapeutic efficacy.
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