LIU Meiying,FU Xiaofang,GUO Yan,et al.WANG Shaojie's exploration of TCM pathogenesis evolution and treatment strategies for alcoholic liver disease based on the theory of body and function[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(08):1044-1047.
LIU Meiying,FU Xiaofang,GUO Yan,et al.WANG Shaojie's exploration of TCM pathogenesis evolution and treatment strategies for alcoholic liver disease based on the theory of body and function[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(08):1044-1047. DOI: 10.16025/j.1674-1307.2025.08.020.
WANG Shaojie's exploration of TCM pathogenesis evolution and treatment strategies for alcoholic liver disease based on the theory of body and function
Professor WANG Shaojie, from the perspective of traditional Chinese medicine (TCM) that "the liver is
yin
in body and
yang
in function", proposes that the evolution of the core pathogenesis of alcoholic liver disease can be divided into three stages. In the early stage, alcohol-induced dampness-heat damages the liver's
yin
blood, impairing qi movement. In the middle stage, toxin stagnation obstructs the liver collaterals, resulting in disharmony between body and function. In the late stage, prolonged illness affects the
yin
essence of the spleen, kidneys, and heart, leading to deficiency of essence and blood, depletion of the heart spirit, and damage to both
yin
and
yang
, which easily gives rise to complications. Clinically, physicochemical examination results are used to objectively analyze abnormalities of the
zangfu
organs and the degree of impairment of their functions, thereby strengthening patients' awareness of self-health management, identifying causes through syndrome differentiation, and accurately targeting the pathogenesis. In treatment, he advocates an approach that addresses both body and function, harmonizes
yin
and
yang
, expels toxins and removes blood stasis, supports the healthy qi and dredges collaterals, thereby ensuring sufficiency of liver blood and essence, unobstructed
qi
and blood flow, effective detoxification, and achieving remarkable therapeutic outcomes.
XU H , XIAO P , ZHANG F , et al . Epidemic characteristics of alcohol-related liver disease in Asia from 2000 to 2020: A systematic review and meta-analysis [J ] . Liver Int , 2022 , 42 ( 9 ): 1991 - 1998 .
SARIN SK , KUMAR M , ESLAM M , etal . Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission [J ] . Lancet Gastroenterol Hepatol , 2020 , 5 ( 2 ): 167 - 228 .
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Related Author
CHEN Mengzhu
SHI Li
ZOU Quan
HU Shaodan
WANG Ziyuan
WANG Tan
GUO Liya
FANG Keying
Related Institution
The Affiliated Hospital of Changchun University of Chinese Medicine
Malianwa Community Health Service Center, Haidian District
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Department of Spleen and Stomach Diseases (Digestive Department), Wangjing Hospital, China Academy of Chinese Medical Sciences
Department of Traditional Chinese Medicine, Putuo District People's Hospital Affiliated to Tongji University