Original meaning of <italic style="font-style: italic">Guizhi Shaoyao Zhimu Decoction</italic> based on the paradigm of "disease, pulse, syndrome, and treatment"

PU Zhenqing; PANG Bo

doi:10.16025/j.1674-1307.2025.11.015

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Original meaning of Guizhi Shaoyao Zhimu Decoction based on the paradigm of "disease, pulse, syndrome, and treatment"

更新时间：2026-01-29

- Original meaning of Guizhi Shaoyao Zhimu Decoction based on the paradigm of "disease, pulse, syndrome, and treatment"
- Beijing Journal of Traditional Chinese Medicine Vol. 44, Issue 11, Pages: 1449-1453(2025)
- 作者机构：
  
  中国中医科学院西苑医院肿瘤科，北京 100091
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2025.11.015
  CLC：
- Received：16 December 2024，
  
  Published：25 November 2025
- 稿件说明：
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普振清，庞博.基于“病脉证治”思维探析桂枝芍药知母汤方证本义［J］.北京中医药，2025，44（11）：1449-1453.

PU Zhenqing,PANG Bo.Original meaning of Guizhi Shaoyao Zhimu Decoction based on the paradigm of "disease, pulse, syndrome, and treatment"[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(11):1449-1453.
普振清，庞博.基于“病脉证治”思维探析桂枝芍药知母汤方证本义［J］.北京中医药，2025，44（11）：1449-1453. DOI： 10.16025/j.1674-1307.2025.11.015.

PU Zhenqing,PANG Bo.Original meaning of Guizhi Shaoyao Zhimu Decoction based on the paradigm of "disease, pulse, syndrome, and treatment"[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(11):1449-1453. DOI： 10.16025/j.1674-1307.2025.11.015.

摘要

桂枝芍药知母汤首见于《金匮要略》，古今医家多认为此方专为风寒湿邪郁而化热所设。基于张仲景“病脉证治”的诊疗思维，结合《黄帝内经》“八风”与卫气相关理论，认为桂枝芍药知母汤证核心病机为“经络虚，风邪入”。方证诸症状表现皆不离“虚风伤卫”之机转，风入六经，卫气不行则肢节疼痛羸弱、腰脊强、脚肿；风闭九窍，气机失调则头眩、短气、欲吐；故治在祛风邪而调卫、补经络而益卫。凡证属营阴精津亏损、风邪内入之关节病症，临证时均可考虑选用本方。

Abstract

Guizhi Shaoyao Zhimu Decoction

was first recorded in the

Medical Treasures of the Golden Chamber

. Historically and presently， many clinicians consider this formula specifically designed for the heat arising from the transformation of wind， cold， and dampness. Based on ZHANG Zhongjing's diagnostic and therapeutic approach of "disease， pulse， syndromed and treatment"， and combined with the theories of the "eight winds" and defense

Huangdi's Internal Classic

， the core pathogenesis of the syndromes of

Guizhi Shaoyao Zhimu Decoction

is considered to be "meridian and collateral deficiency with invasion of pathogenic wind". All symptoms of the syndromes reflect the mechanism of "deficient wind harming the defense

"， specifically， when wind enters the six meridians and obstructs defense

， it leads to joint pain and weakness， stiffness of the spine， and swelling of the feet； when wind blocks the nine orifices，

becomes unbalanced， causing dizziness， shortness of breath， and nausea. Therefore， treatment focuses on expelling pathogenic wind， regulating the defense

， and tonifying the meridians and collaterals to benefit the defense

. Clinically， this formula may be applied to joint disorders characterized by depletion of nutrient

yin

， essence， and body fluids， accompanied by the internal invasion of wind pathogens. This formula may be considered in clinical practice.

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references

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Original meaning of Guizhi Shaoyao Zhimu Decoction based on the paradigm of "disease, pulse, syndrome, and treatment"

DOI：10.16025/j.1674-1307.2025.11.015

摘要

Abstract

关键词

Keywords

references