ZHANG Shengsheng's experience in treating chronic atrophic gastritis and precancerous lesions of gastric cancer by using ternary combinations of herbal drugs based on the "regulating states and resolving masses"

WANG Aling; LI Danyan; ZHANG Shengsheng

doi:10.16025/j.1674-1307.2025.12.013

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ZHANG Shengsheng's experience in treating chronic atrophic gastritis and precancerous lesions of gastric cancer by using ternary combinations of herbal drugs based on the "regulating states and resolving masses"

更新时间：2026-01-24

- ZHANG Shengsheng's experience in treating chronic atrophic gastritis and precancerous lesions of gastric cancer by using ternary combinations of herbal drugs based on the "regulating states and resolving masses"
- Beijing Journal of Traditional Chinese Medicine Vol. 44, Issue 12, Pages: 1576-1580(2025)
- 作者机构：
  
  首都医科大学附属北京中医医院，北京 100010
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2025.12.013
  CLC：
- Received：11 February 2025，
  
  Published：25 December 2025
- 稿件说明：
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王阿玲，李丹艳，张声生.张声生基于“调态消癥”法运用角药治疗慢性萎缩性胃炎及胃癌前病变的经验［J］.北京中医药，2025，44（12）：1576-1580.

WANG Aling,LI Danyan,ZHANG Shengsheng.ZHANG Shengsheng's experience in treating chronic atrophic gastritis and precancerous lesions of gastric cancer by using ternary combinations of herbal drugs based on the "regulating states and resolving masses"[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(12):1576-1580.
王阿玲，李丹艳，张声生.张声生基于“调态消癥”法运用角药治疗慢性萎缩性胃炎及胃癌前病变的经验［J］.北京中医药，2025，44（12）：1576-1580. DOI： 10.16025/j.1674-1307.2025.12.013.

WANG Aling,LI Danyan,ZHANG Shengsheng.ZHANG Shengsheng's experience in treating chronic atrophic gastritis and precancerous lesions of gastric cancer by using ternary combinations of herbal drugs based on the "regulating states and resolving masses"[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(12):1576-1580. DOI： 10.16025/j.1674-1307.2025.12.013.

摘要

角药是在中医理论指导下，以辨证论治为前提，将三味中药恰当组合的特殊配伍形式，或相反相成，或相互协同，以达减毒增效的目的。慢性萎缩性胃炎（CAG）及胃癌前病变（PLGC）是消化系统的常见病、疑难病，有进展为胃癌的风险。张声生教授诊治CAG及PLGC经验丰富，将本病病机总结为“虚、浊、滞、瘀、毒、癥”，提出“调态消癥”的治法，并基于此治法精准配伍，合理运用角药治疗，临证多有效验。

Abstract

Ternary combination of herbal drugs is a special form of herbal combination guided by traditional Chinese medicine theory and based on syndrome differentiation and treatment. It involves the appropriate combination of three Chinese herbs， which may mutually enhance or counteract each other， with the purpose of reducing toxicity and enhancing efficacy. Chronic atrophic gastritis （CAG） and precancerous lesions of gastric cancer （PLGC） are common and challenging digestive diseases with a risk of progression to gastric cancer. Professor ZHANG Shengsheng has extensive experience in the diagnosis and treatment of CAG and PLGC. He summarizes the pathogenesis of these conditions as "deficiency， turbidity， stagnation， stasis， toxin， and masses"， and proposes the therapeutic method of "regulating states and resolving masses". Based on this method， he applies ternary combinations of herbal drugs rationally and accurately， achieving effective clinical outcomes in most cases.

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references

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