Fatigue in yang deficiency constitution and warming-yang constitutional regulation strategies from the perspective of “yang qi insufficiency-dysregulation of the energy-metabolism network”
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Fatigue in yang deficiency constitution and warming-yang constitutional regulation strategies from the perspective of “yang qi insufficiency-dysregulation of the energy-metabolism network”
Beijing Journal of Traditional Chinese MedicineVol. 44, Issue 12, Pages: 1601-1604(2025)
CUI Shien,QIN Junjun,LI Yan,et al.Fatigue in yang deficiency constitution and warming-yang constitutional regulation strategies from the perspective of “yang qi insufficiency-dysregulation of the energy-metabolism network”[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(12):1601-1604.
CUI Shien,QIN Junjun,LI Yan,et al.Fatigue in yang deficiency constitution and warming-yang constitutional regulation strategies from the perspective of “yang qi insufficiency-dysregulation of the energy-metabolism network”[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(12):1601-1604. DOI: 10.16025/j.1674-1307.2025.12.019.
Fatigue in yang deficiency constitution and warming-yang constitutional regulation strategies from the perspective of “yang qi insufficiency-dysregulation of the energy-metabolism network”
Based on the "constitution-disease correlation" theory in traditional Chinese medicine, this paper proposes that "
yang qi
insufficiency-dysregulation of the energy-metabolism network" is the core pathogenesis linking
yang
-deficient constitution and fatigue.
Yang
-deficient constitution is considered the underlying basis for the development of fatigue, characterized by diminished
yang
-mediated warming and mobilizing functions, leading to multi-level disturbances in energy metabolism, from neuroendocrine regulation to cellular bioenergetics. Based on this pathogenic understanding, the fundamental therapeutic principle of "warming
yang
to regulate constitution" is established to activate energy, providing a novel perspective for the prevention and management of fatigue from the viewpoint of TCM body consti
LEONG PK , WONG HS , CHEN J , et al . Yang/Qi invigoration:an herbal therapy for chronic fatigue syndrome with yang deficiency [J ] . Evid Based Complement Alternat Med , 2015 : 945901 .
SWEETMAN E , KLEFFMANN T , EDGAR C , et al . A SWATH-MS analysis of myalgic encephalomyelitis/chronic fatigue syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction [J ] . Transl Med . 2020 , 18 ( 1 ): 365 .