Pathogenesis and treatment of diabetes cognitive impairment based on the "<italic style="font-style: italic">Xuanfu</italic> theory"

LI Runqi; ZHAO Yi; LIU Lantian; WU Rui; XU Bingrui; YE Zimengwei; ZHAO Dandan; GAO Sihua

doi:10.16025/j.1674-1307.2026.01.020

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Pathogenesis and treatment of diabetes cognitive impairment based on the "Xuanfu theory"

更新时间：2026-04-01

- Pathogenesis and treatment of diabetes cognitive impairment based on the "Xuanfu theory"
- Beijing Journal of Traditional Chinese Medicine Vol. 45, Issue 1, Pages: 116-120(2026)
- 作者机构：
  
  1.北京中医药大学中医学院，北京 100029
  2.中国中医科学院广安门医院南区内分泌科，北京 100053
  3.保定幼儿师范高等专科学校，保定 072700
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2026.01.020
  CLC：
- Received：29 August 2025，
  
  Published：25 January 2026
- 稿件说明：
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李润琪，赵祎，刘蓝天，等.玄府学说视角下糖尿病认知障碍的病机与治疗探析［J］.北京中医药，2026，45（1）：116-120.

LI Runqi,ZHAO Yi,LIU Lantian,et al.Pathogenesis and treatment of diabetes cognitive impairment based on the "Xuanfu theory"[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(01):116-120.
李润琪，赵祎，刘蓝天，等.玄府学说视角下糖尿病认知障碍的病机与治疗探析［J］.北京中医药，2026，45（1）：116-120. DOI： 10.16025/j.1674-1307.2026.01.020.

LI Runqi,ZHAO Yi,LIU Lantian,et al.Pathogenesis and treatment of diabetes cognitive impairment based on the "Xuanfu theory"[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(01):116-120. DOI： 10.16025/j.1674-1307.2026.01.020.

摘要

糖尿病认知障碍（DACI）是糖尿病的重要并发症之一，主要表现为记忆力减退、执行功能障碍及注意力下降。现代医学对其发病机制的认识目前尚不明确。玄府学说认为，玄府是周身孔窍，是气血津液精神之通路，可为DACI的病机提供新的理论解释。DACI的发生发展以玄府郁闭为关键病理环节。玄府闭郁导致气血津液运行受阻，脑玄府不通，神机失调，导致认知功能下降。在治疗上，应以开通玄府为核心治则，其中发散开玄与通下开玄两法尤为重要，二者相辅相成，分别从表与里、上与下两方面调畅气机、疏解郁闭，调和阴阳以恢复玄府功能。

Abstract

Diabetes cognitive impairment （DCI） is an important complication of diabetes mellitus， primarily manifested as memory decline， executive dysfunction， and decreased attention. The pathogenesis of DCI remains unclear in modern medicine. According to the

Xuanfu

theory，

Xuanfu

refers to the body's orifices， serving as pathways for

， blood， fluids， and spirit， and provides a new theoretical explanation for the pathogenesis of DCI. The occurrence and development of DCI are primarily related to the obstruction of

Xuanfu

blockage leads to impaired circulation of

， blood， and fluids， resulting in dysfunction of the brain's

Xuanfu

and disordered mental activity， which in turn causes cognitive decline. In treatment， opening the

Xuanfu

is the core principle. Among the methods， dispersing and opening the upper

Xuanfu

and clearing and opening the lower

Xuanfu

are especially important. These two approaches complement each other， regulating

from the exterior and interior， upper and lower aspects， resolving obstruction， harmonizing yin and yang， and restoring

Xuanfu

function.

关键词

Keywords

references

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⁰

Pathogenesis and treatment of diabetes cognitive impairment based on the "Xuanfu theory"

DOI：10.16025/j.1674-1307.2026.01.020

摘要

Abstract

关键词

Keywords

references