A non-inferiority clinical study of press-needle versus filiform-needle therapy for chronic tic disorder in children at the same frequency

LYU Xiaoqin; MAO Gai; CHANG Ying; HUANG Guimin; WANG Zhongyi; LIU Qingquan

doi:10.16025/j.1674-1307.2026.04.003

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A non-inferiority clinical study of press-needle versus filiform-needle therapy for chronic tic disorder in children at the same frequency

更新时间：2026-06-10

- A non-inferiority clinical study of press-needle versus filiform-needle therapy for chronic tic disorder in children at the same frequency
- Beijing Journal of Traditional Chinese Medicine Vol. 45, Issue 4, Pages: 444-447(2026)
- 作者机构：
  
  1.首都医科大学附属首都儿童医学中心中医科，北京 100020
  2.首都儿科研究所大数据研究中心，北京 100020
  3.首都医科大学附属北京中医医院儿科，北京 100010
  4.首都医科大学附属北京中医医院，北京 100010
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2026.04.003
  CLC：
- Received：24 January 2025，
  
  Published：25 April 2026
- 稿件说明：
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吕小琴，毛改，常莹，等.同频次下揿针与毫针治疗儿童抽动障碍的非劣效性临床研究［J］.北京中医药，2026，45（4）：444-447.

LYU Xiaoqin,MAO Gai,CHANG Ying,et al.A non-inferiority clinical study of press-needle versus filiform-needle therapy for chronic tic disorder in children at the same frequency[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(04):444-447.
吕小琴，毛改，常莹，等.同频次下揿针与毫针治疗儿童抽动障碍的非劣效性临床研究［J］.北京中医药，2026，45（4）：444-447. DOI： 10.16025/j.1674-1307.2026.04.003.

LYU Xiaoqin,MAO Gai,CHANG Ying,et al.A non-inferiority clinical study of press-needle versus filiform-needle therapy for chronic tic disorder in children at the same frequency[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(04):444-447. DOI： 10.16025/j.1674-1307.2026.04.003.

摘要

目的

观察同频次下揿针与毫针治疗儿童抽动障碍（TD）的临床疗效。

方法

选取2021年2月—2024年4月首都医科大学附属首都儿童医学中心确诊为TD的患儿120例，采用随机数字表法分为揿针组、毫针组、可乐定组各40例。可乐定组给予可乐定透皮贴治疗，揿针组给予揿针针刺+可乐定透皮贴治疗，毫针组给予毫针针刺+可乐定透皮贴治疗，均连续治疗12周。对比3组治疗前及治疗第4、8、12周耶鲁综合抽动严重程度量表（YGTSS）评分，统计治疗期间发生的不良反应。

结果

治疗第4周，3组YGTSS总分减分值比较差异无统计学意义（

0.05）；治疗第8、12周，揿针组、毫针组YGTSS总分减分值均高于可乐定组（

0.05）。3组不良反应发生率比较，差异无统计学意义（

0.05）。

结论

在每周1次频率下治疗12周，揿针与毫针对儿童抽动障碍的疗效相当，均优于单纯可乐定透皮贴治疗，且安全性良好。

Abstract

Objective

To observe the clinical efficacy of press needle versus filiform needle therapy administered at the same frequency in the treatment of children with tic disorder （TD）.

Methods

A total of 120 children diagnosed with TD at the Capital Center for Children's Health，Capital Medical University from February 2021 to April 2024 were enrolled and randomly divided into a press needle group， a filiform needle group， and a clonidine group （

=40 each） using a random number table method. The clonidine group received clonidine transdermal patch therapy. The press needle group received press needle acupuncture combined with clonidine transdermal patch therapy， while the filiform needle group received filiform needle acupuncture combined with clonidine transdermal patch therapy. All groups were treated continuously for 12 weeks. The Yale Global Tic Severity Scale （YGTSS） scores were compared among the three groups before treatment and at weeks 4， 8， and 12. Adverse events during treatment were recorded.

Results

At week 4， there was no

statistically significant difference in the reduction of total YGTSS scores among the three groups （

0.05）. At weeks 8 and 12， the reductions in total YGTSS scores in the press needle group and filiform needle group were both greater than those in the clonidine group （

0.05）. There was no statistically significant difference in the incidence of adverse events among the three groups （

0.05）.

Conclusion

With once-weekly treatment for 12 weeks， press needle and filiform needle therapies show comparable efficacy in children with TD， both superior to clonidine transdermal patch monotherapy， with good safety profiles.

关键词

Keywords

references

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