ZHANG Sizheng,CAO Dezhong,SU Liang,et al.Pathogenesis and treatment of functional impotence based on the theory of "unity of form and spirit"[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(04):503-506.
ZHANG Sizheng,CAO Dezhong,SU Liang,et al.Pathogenesis and treatment of functional impotence based on the theory of "unity of form and spirit"[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(04):503-506.DOI: 10.16025/j.1674-1307.2026.04.015.
Pathogenesis and treatment of functional impotence based on the theory of "unity of form and spirit"
Functional impotence is a common male sexual dysfunction in clinical practice, which seriously affects patients' physical and mental health as well as their quality of life. "Unity of form and spirit" is one of the important theories in traditional Chinese medicine (TCM). Our team considers functional impotence to be a typical disorder characterized by the coexistence of form and spirit pathology. Its pathogenesis is dominated by disturbance of the spirit, with
qi
deficiency serving as a prerequisite for disease onset, while dysregulation of form and the internal generation of blood stasis represent the pathological changes in the later stage. Based on the theory of "unity of form and spirit", it is proposed that treatment should focus on regulating the spirit, tonifying
qi
, removing blood stasis, and relieving emotional disturbances, so as to comprehensively regulate functional impotence and ultimately achieve the integrated treatment of form and spirit, and the harmonization of body and mind.
JIANG R . Analyzing a recent study on erectile dysfunction: perspective on "Erectile dysfunction prevalence in the United States: report from the 2021 National Survey of Sexual Wellbeing" [J ] . J Sex Med , 2025 , 22 ( 12 ): 2164 .
ZHANG S X , LUTAS A , YANG S , et al . Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling [J ] . Nature , 2021 , 597 ( 7875 ): 245 - 249 .
KÜHN S , GALLINAT J . A quantitative meta-analysis on cue-induced male sexual arousal [J ] . J Sex Med , 2011 , 8 ( 8 ): 2269 - 2275 .
LIU Q , ZHANG Y , WANG J , et al . Erectile dysfunction and depression: a systematic review and meta-analysis [J ] . J Sex Med , 2018 , 15 ( 8 ): 1073 - 1082 .
SAHU MK , DUBEY RK , CHANDRAKAR A , et al . A systematic review and meta-analysis of serum and plasma cortisol levels in depressed patients versus control [J ] . Indian J Psychiatry , 2022 , 64 ( 5 ): 440 - 448 .
LATTIN CR , KELLY TR . Glucocorticoid negative feedback as a potential mediator of trade-offs between reproduction and survival [J ] . Gen Comp Endocrinol . 2020 , 286 : 113301 .
BELLINGHIERI G , SANTORO G , SANTORO D , et al . Ultrastructural changes of corpora cavernosa in men with erectile dysfunction and chronic renal failure [J ] . Semin Nephrol , 2004 , 24 ( 5 ): 488 - 491 .
AYDOS K , BALTACI S , SAĞLAM M , et al . Ultrastructual changes of corpora cavernosa in vascular erectile dysfunction [J ] . Int Urol Nephrol , 1996 , 28 ( 3 ): 375 - 385 .
A non-inferiority clinical study of press-needle versus filiform-needle therapy for chronic tic disorder in children at the same frequency
Experience in differentiating and treating female functional constipation from the perspective of blood
Jianpi Yiqi Shexue Formula in treatment of thrombocytopenia after CAR-T for diffuse large B-cell lymphoma
Preliminary exploration of the experience in differentiating and treating Hailey-Hailey disease based on the theory of "healthy qi deficiency and latent pathogens"
Differentiation and treatment of granulomatous mastitis by the Yanjing School of Surgery based on the theory of nursing the field