ZHANG Xinyue,JI Xingyu,ZHAO Lu,et al.Clinical treatment of Crohn's disease based on Treatise on Cold Damage and Miscellaneous Diseases[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(04):554-559.
ZHANG Xinyue,JI Xingyu,ZHAO Lu,et al.Clinical treatment of Crohn's disease based on Treatise on Cold Damage and Miscellaneous Diseases[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(04):554-559.DOI: 10.16025/j.1674-1307.2026.04.027.
Clinical treatment of Crohn's disease based on Treatise on Cold Damage and Miscellaneous Diseases
Crohn's disease is a chronic inflammatory bowel disease characterized by abdominal pain, diarrhea, and hematochezia, which seriously affects patients' quality of life. Based on the theories of the
Treatise on Cold Damage and Miscellaneous Diseases
, this article discusses traditional Chinese medicine (TCM) treatment strategies for Crohn's disease. For the syndrome of dampness-heat accumulation, treatment should focus on clearing heat, eliminating dampness, resolving blood stasis, and removing toxin, with representative prescriptions such as
Huangqin Decoction
and
Baitouweng Decoction
. For the syndrome of liver-spleen disharmony, treatment should aim to soothe the liver, regulate the spleen, and promote the smooth flow of
qi
, using prescriptions such as
Sini Powder
or
Chaihu Guizhi Decoction
. For the syndrome involving a mixture of cold and heat, treatment should combine warming and cooling methods as well as reinforcing and reducing therapies, with prescriptions such as
Banxia Xiexin Decoction
and
Wumei Pills
. For the syndrome of
yang
deficiency with cold coagulation, treatment should focus on replenishing
qi
, warming
yang
, astringing the intestines, and securing against prolapse, using prescriptions such as
XU L , HE B , SUN Y , et al . Incidence of inflammatory bowel disease in urban China: a nationwide population-based study [J ] . Clin Gastroenterol Hepatol , 2023 , 21 ( 13 ): 3379 - 3386.e29 .
ZHANG S , ZHONG R , TANG S , et al . Metabolic regulation of the Th17/Treg balance in inflammatory bowel disease [J ] . Pharmacol Res , 2024 , 203 : 107184 .
NONG F , LUO S , LIANG Y , et al . Evaluation of the effect of Dahuang-Mudan decoction on TNBS-induced colitis using UPLC-QTOF/MS-based metabolomic analysis [J ] . Biomed Chromatogr , 2021 , 35 ( 3 ): e5003 .
YANG J , MIAO L , XUE Y , et al . Yiyi Fuzi Baijiang Powder alleviates dextran sulfate sodium-induced ulcerative colitis in rats via inhibiting the TLR4/NF-κB/NLRP3 inflammasome signaling pathway to repair the intestinal epithelial barrier, and modulating intestinal microbiota [J ] . Oxid Med Cell Longev , 2023 : 3071610 .
CAI Y , LI X , HAN Q , et al . Si-Ni-San improves experimental colitis by favoring Akkermensia colonization [J ] . J Ethnopharmacol , 2023 , 305 : 116067 .
YU W , LIANG Z , LI Q , et al . The pharmacological validation of the Xiao-Jian-Zhong formula against ulcerative colitis by network pharmacology integrated with metabolomics [J ] . J Ethnopharmacol , 2022 , 298 : 115647 .
CAI Lianxiang's experience in treating fat liquefaction of incision after gynecological abdominal surgical by "Tuobu method"
Clinical application of Hyperici Perforati Herba-Acanthopanacis Senticosi Radix et Rhizoma Seu Caulis herb pair in coronary heart disease with depression based on "deficiency, stasis, and depression"
"Eight methods of abdomen Tuina" in the treatment of dizziness based on circular movement
TCM clinical characteristics, etiology, and pathogenesis of ANCA-associated vasculitis with lung and kidney involvement
Experience in differentiating and treating female functional constipation from the perspective of blood