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- 0 1 Traditional Chinese medicine clinical practice guidelines for Type Ⅲ prostatitis (2024) 2799
- 0 2 Clinical application experience of Qianyang Fengsui Dan combined with Yinhuo Decoction based on “minister fire theory” 2675
- 0 3 Integrated diagnosis and treatment plan for Hashimoto's thyroiditis with integrated traditional Chinese and western medicine 2444
- 0 4 Traditional Chinese Medicine diagnosis and treatment scheme for pulmonary fibrosis 2028
- 0 5 Beijing expert consensus on the integrated Chinese and western medicine treatment of Granulomatous mastitis (2025) 1774
- 0 6 Integrative Chinese and western medicine diagnosis and treatment program for Helicobacter pylori infection 1737
- 0 7 Precise syndrome differentiation and treatment approaches for male erectile dysfunction on different stages with integration of traditional Chinese and western medicine 1474
- 0 8 Exploration of the culture of Tongjitang pharmaceutical catalogue 1441
- 0 9 Syndrome differentiation and treatment of premature ejaculation based on the theory of “Yinhuo” in five viscera 1435
- 10 Diagnosis and treatment scheme of integrated traditional Chinese medicine and western medicine for epilepsy 1328
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2026年第45卷第6期
- 摘要：ObjectiveTo investigate the therapeutic efficacy and safety of different massage manipulations for constipation in patients with qi deficiency type constipation after stroke.MethodsA total of 200 patients with qi deficiency type constipation after stroke who were admitted to Dongfang Hospital of Beijing University of Chinese Medicine from September 2023 to May 2024 were selected and randomly divided into a control group， an observation group A （tonifying manipulation）， an observation group B （purging manipulation）， and an observation group C （combined tonifying-purging manipulation） according to a random number table， with 50 patients in each group. The control group received routine nursing combined with oral Biantong Tablets for constipation relief. On the basis of the treatment provided to the control group， the observation groups received constipation massage interventions using tonifying manipulation， purging manipulation， and combined tonifying-purging manipulation， respectively， for 14 days. Constipation severity （CCS score）， qi deficiency syndrome score， and Patient Assessment of Constipation Quality of Life （PAC-QOL） score were observed and compared among the groups on days 7 and 14 of treatment. After 14 days of treatment， clinical efficacy and adverse reactions were evaluated and compared among the groups.ResultsAfter 14 days of treatment， CCS and PAC-QOL scores were significantly improved in all four groups compared with those before treatment. Intergroup comparisons showed that the improvements in the above indicators in observation groups A and C were significantly greater than those in the control group and observation group B （P<0.01）， whereas there were no significant differences in any of the indicators between observation group B and the control group （P>0.05）. Regarding qi deficiency syndrome scores， no significant improvement was observed in the control group or observation group B after treatment （P>0.05）. The qi deficiency syndrome scores in observation groups A and C were significantly decreased compared with those before treatment and were significantly lower than those in the control group and observation group B at the corresponding time points （P<0.05）. Moreover， the improvement in observation group C was significantly greater than that in observation group A （P<0.05）. Regarding clinical efficacy， the total effective rates in observation groups A and C were significantly higher than that in the control group， while the total effective rate and proportion of markedly effective cases in observation group C were higher than those in observation group A （P<0.05）. There was no significant difference in clinical efficacy between observation group B and the control group （P>0.05）. Regarding safety， three cases of abdominal distension and diarrhea occurred in the control group， whereas no obvious adverse reactions occurred in any of the massage intervention groups， indicating better safety.ConclusionBoth tonifying manipulation and combined tonifying-purging constipation massage can effectively improve constipation symptoms， qi deficiency syndrome， and quality of life in patients with qi deficiency type constipation after stroke. Combined tonifying-purging manipulation has the best therapeutic efficacy and favorable safety and is worthy of clinical promotion and application.关键词：massage manipulations for constipation;stroke;qi deficiency type constipation67|14|0更新时间：2026-09-04
- 摘要：ObjectiveTo observe the clinical efficacy of Dianbo tendon-regulating manipulation combined with floating needling therapy in the treatment of rotator cuff injury.MethodsA total of 74 patients with rotator cuff injury who were admitted to the Department of Acupuncture， Moxibustion， and Tuina， Chongqing Tongliang District Hospital of Traditional Chinese Medicine， from January 2022 to June 2024 were selected and divided into an observation group and a control group using the random number table method， with 37 patients in each group. The observation group received Dianbo tendon-regulating manipulation combined with floating needling therapy， while the control group received Maitland joint mobilization. Both groups were treated once daily， with 10 days constituting one treatment course， for a total of two treatment courses， with a 1-day interval between the two courses. Pain severity was assessed using the Visual Analogue Scale （VAS）， shoulder joint function was assessed using the University of California， Los Angeles （UCLA） Shoulder Rating Scale， and shoulder range of motion （ROM） was measured before treatment， at the end of treatment， and at 3 and 6 months after treatment. Clinical efficacy was compared between the two groups at the end of treatment and at 3 and 6 months after treatment.ResultsCompared with conditions before treatment， VAS scores were significantly decreased， while UCLA scores and ROM were significantly increased in both groups at the end of treatment and at 3 and 6 months after treatment （P<0.05）. Compared with the control group， the observation group showed significantly greater improvements in VAS scores， UCLA scores， and ROM at the end of treatment and at 3 and 6 months after treatment （P<0.05）. At the end of treatment and at 3 and 6 months after treatment， the clinical efficacy of the observation group was superior to that of the control group （P<0.05）， and the rate of marked effectiveness and healing was higher than that of the control group （P<0.05）.ConclusionDianbo tendon-regulating manipulation combined with floating needling therapy has significant efficacy in treating rotator cuff injury， effectively relieving pain and improving shoulder joint range of motion.关键词：rotator cuff injury;Dianbo tendon-regulating manipulation;floating needling therapy;Maitland joint mobilization;clinical efficacy17|4|0更新时间：2026-09-04
- 摘要：ObjectiveTo explore the distribution characteristics of traditional Chinese medicine （TCM） syndromes in primary hypertension in Fujian region based on cluster analysis.MethodsThe four diagnostic information of 976 patients with primary hypertension was collected， and the K-means clustering method was used to summarize the distribution characteristics of TCM syndromes in primary hypertension.ResultsAmong patients with primary hypertension in Fujian region， liver yang hyperactivity syndrome was the most common （45.28%）， followed by phlegm-dampness internal obstruction syndrome （19.36%） and liver qi stagnation with spleen deficiency syndrome （13.62%）. The symptoms of primary hypertension， ranked by frequency from highest to lowest， were dizziness， chest tightness， dry mouth， poor sleep， and irritability. The predominant pulse patterns were wiry and slippery， while the predominant tongue manifestations were a red tongue and yellow coating. K-means clustering analysis classified the TCM syndromes of primary hypertension into five categories， each reflecting the distribution characteristics of different syndrome types， including excess， deficiency-excess complex， and deficiency patterns.ConclusionLiver yang hyperactivity syndrome is predominant among patients with primary hypertension in Fujian region. K-means clustering can classify the TCM syndromes into different types， including predominantly excess， deficiency-excess complex， and predominantly deficiency syndromes.关键词：primary hypertension;traditional Chinese medicine syndromes;cluster analysis;liver yang hyperactivity syndrome;phlegm-dampness internal obstruction syndrome9|4|0更新时间：2026-09-04
- 摘要：ObjectiveTo observe the clinical efficacy of Huize Shulinggan Liquid drip irrigation for the treatment of anastomotic leakage （AL） following colorectal cancer surgery.MethodsA total of 89 patients with AL following colorectal cancer surgery who were treated in the Department of Anorectal Surgery， Huanghua People's Hospital， from November 2017 to December 2024 were retrospectively included. According to the treatment method， the patients were divided into a control group （n=27） and an observation group （n=62）. Intervention was initiated immediately after the patient's body temperature increased. The control group received conventional treatment， while the observation group received Huize Shulinggan Liquid drip irrigation. The two groups were compared in terms of time to control of infection symptoms， time to resumption of enteral nutrition， AL healing time， and the numbers of deaths， cases of AL healing， cases of cholestasis， and intestinal diversion procedures.ResultsThe times to control of infection symptoms， resumption of enteral nutrition， and AL healing were shorter in the observation group than in the control group （all P<0.05）. No deaths occurred in either group. In the observation group， AL healed in 60 cases （97.6%）， with 1 case of cholestasis and 2 cases requiring intestinal diversion； in the control group， AL healed in 9 cases （33.3%）， with 10 cases of cholestasis and 18 cases requiring intestinal diversion. The AL healing rate was higher in the observation group than in the control group （P<0.05）.ConclusionHuize Shulinggan Liquid drip irrigation for the treatment of AL following colorectal cancer surgery can shorten the time to resumption of enteral nutrition and control of infection symptoms， increase the healing rate with conservative treatment， and reduce the incidence of cholestasis.关键词：colorectal cancer;anastomotic leakage;Huize Shulinggan Liquid;drip irrigation therapy8|6|0更新时间：2026-09-04
- 摘要：ObjectiveTo investigate the effects of Tangluoning （TLN） on abnormal cholesterol metabolism in Schwann cells （SCs） with mitochondrial thioredoxin 2 （Trx2） deficiency and its underlying mechanisms.MethodsCell experiment： SCs were divided into the blank control （Control） group， siRNA （Trx2 siRNA） group， and siRNA+TLN （TLN-medicated serum） group. High-content analysis was used to detect changes in cellular cholesterol and myelin basic protein （MBP） levels and the expression of cholesterol synthesis-related proteins， including 3β-hydroxysteroid-Δ⁸，Δ⁷-isomerase （EBP）， lanosterol synthase （LSS）， and hydroxysteroid 17-β dehydrogenase （HSD17B7）. Western blot （WB） was used to determine the protein level of lanosterol 14-α-demethylase （CYP51A）. Animal experiment： On this basis， sciatic nerve sections from rats in the blank control （C）， model control （DPN）， α-lipoic acid （ALA）， and TLN groups were collected， and immunofluorescence was used to detect the expression of LSS， CYP51A， HSD17B7， and EBP proteins.ResultsCell experiment： High-content analysis showed that， compared with the Control group， the siRNA group had significantly increased cholesterol content （P<0.01） and significantly decreased MBP protein expression （P<0.01）. Compared with the Trx2 siRNA group， the Trx2 siRNA+TLN group had significantly decreased cholesterol content （P<0.01） and significantly increased MBP protein expression （P<0.01）. Western blot showed that， compared with the Control group， the protein levels of CYP51A， EBP， LSS， and HSD17B7 were significantly increased in the Trx2 siRNA group （P<0.05，P<0.01）. Compared with the Trx2 siRNA group， the Trx2 siRNA+TLN group showed significantly decreased protein expression levels of CYP51A， EBP， and LSS （P<0.05， P<0.01）. Animal experiment： Immunofluorescence results of rat sciatic nerves showed that， compared with the C group， the DPN group had significantly increased protein expression levels of EBP， LSS， HSD17B7， and CYP51A （P<0.05， P<0.01）. Compared with the DPN group， the TLN and ALA groups both showed significantly decreased protein expression levels of EBP， LSS， HSD17B7， and CYP51A （P<0.01）.ConclusionTLN can reduce cholesterol accumulation in SCs and promote MBP expression by inhibiting the expression of the cholesterol metabolism-related proteins LSS， CYP51A， and EBP in Trx2-deficient SCs， which may be one of the mechanisms by which TLN ameliorates demyelination in diabetic peripheral neuropathy （DPN）.关键词：Tangluoning;Schwann cells;diabetic peripheral neuropathy;cholesterol;mitochondrial thioredoxin13|9|0更新时间：2026-09-04
- 摘要：ObjectiveTo investigate the mechanisms underlying the effects of Qianlong Shutong Formula （QLSTF） in the treatment of benign prostatic hyperplasia （BPH） based on metabolomics.MethodsA total of 30 male Sprague-Dawley （SD） rats were selected and randomly divided into a blank group， model group， and Chinese medicine group. The BPH model was established by surgery combined with continuous injections of testosterone propionate， and the Chinese medicine group received QLSTF by gavage. The pathological status of prostate tissue was evaluated by histopathological staining. Serum and prostate metabolomics were analyzed using liquid chromatography-mass spectrometry. Bioinformatics analysis was used to identify differential metabolites.ResultsSignificant differences were observed in the types and numbers of metabolites among the groups. KEGG enrichment analysis showed significant differences in arginine and proline metabolism between the model group and the blank group. In contrast， the differences between the Chinese medicine group and the model group were mainly associated with cholesterol， tyrosine， bile secretion， and bile acid synthesis.ConclusionThe identification of differential metabolites may help reveal potential biomarkers for the treatment of BPH， provide insights for subsequent mechanistic studies， and provide new evidence for the treatment of BPH.关键词：benign prostatic hyperplasia;Qianlong Shutong Formula;liquid chromatography-mass spectrometry analysis;metabolomics;experimental study5|5|0更新时间：2026-09-04
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