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Volume 45 期 1，2026 2026年第45卷第1期

    SHI Wen, MA Haijuan, HE Jintao, DONG Lei, LIU Yao, ZHAO Huiling, XING Yuan

    Vol. 45, Issue 1, Pages: 1-5(2026) DOI: 10.16025/j.1674-1307.2026.01.001
    摘要：ObjectiveTo observe the clinical efficacy of Huangjing Jiangya Decoction combined with amlodipine in treating patients with hypertension complicated by anxiety.MethodsA total of 71 patients with primary hypertension of qi-deficiency type and comorbid anxiety， treated at the Traditional Chinese Medicine， Cardiology， and Neurology Outpatient Departments of Beijing Sixth Hospital from May 2022 to November 2023， were randomly divided into an observation group and a control group. The control group received conventional Western medicine treatment with amlodipine besylate tablets 5 mg once daily. The observation group received additional oral administration of self-formulated Huangjing Jiangya Decoction on top of the control regimen. Both groups were treated continuously for 8 weeks. Clinical efficacy， clinic blood pressure， home blood pressure， 24-hour ambulatory blood pressure， GAD-7 score， and TCM syndrome scores before and after treatment were compared between the two groups.ResultsAfter treatment， the total clinical efficacy and total TCM syndrome efficacy in the observation group were higher than those in the control group （both P < 0.01）. Clinic and home blood pressure in the observation group were significantly reduced compared to baseline （both P < 0.05） and were lower than those in the control group （both P < 0.01）. The 24-hour systolic and diastolic blood pressure in the observation group decreased significantly compared to baseline （both P < 0.05） and were lower than those in the control group （both P < 0.01）. The GAD-7 score and TCM syndrome scores in the observation group were significantly lower than before treatment （both P < 0.05） and lower than in the control group （both P < 0.01）. No adverse reactions such as nausea or vomiting were observed during treatment， and liver and kidney function indicators remained normal in both groups.ConclusionHuangjing Jiangya Decoction combined with amlodipine can significantly reduce blood pressure， improve anxiety symptoms and clinical manifestations in patients with qi-deficiency hypertension and anxiety， with overall efficacy superior to amlodipine alone， and demonstrates high safety.  
    关键词：hypertension with anxiety;Qi-deficiency syndrome;Huangjing Jiangya Decoction   
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    更新时间：2026-04-01

    TAN Xinhuan, LIU Huihui, WANG Tianrui, BI Hongzheng, CHU Haibin, YANG Qingmin, YU Dapeng, WANG Fei

    Vol. 45, Issue 1, Pages: 6-10(2026) DOI: 10.16025/j.1674-1307.2026.01.002
    摘要：ObjectiveTo observe the effect of Modified Xugu Huoxue Decoction on mineralized osteogenesis in the treatment of tibial bone transport.MethodsA total of 73 patients with tibial bone defects admitted to Wendeng Orthopedic Hospital， Shandong Province， from January 2018 to August 2023 were selected. Using a random number table， patients were divided into an observation group （37 cases） and a control group （36 cases）. All patients underwent small-incision semicircular osteotomy at the proximal or distal tibia under continuous epidural anesthesia according to the location of the bone defect. Starting from the first postoperative day， the observation group received oral Modified Xugu Huoxue Decoction， with each course lasting 2 weeks for a total of 3 courses. Bone mineral density （BMD） in the lengthening area was compared at 1， 4， 8， 12， and 16 weeks postoperatively. Callus diameter ratio （CDR） was measured at 4， 8， 12， and 16 weeks. Bone healing index was compared at the time of external fixator removal. Functional recovery was evaluated at 1 year postoperatively.ResultsAt 4， 8， 12， and 16 weeks after surgery， BMD in the lengthening area of the observation group was higher than that of the control group （P < 0.05）. At 8， 12， and 16 weeks postoperatively， CDR in the observation group was higher than that in the control group （P < 0.05）. The healing index was （1.208 ± 0.124） in the observation group and （1.594 ± 0.135） in the control group， with the observation group showing a significantly lower index （P < 0.05）. At 1-year follow-up， the rate of excellent and good functional recovery was 89.2% in the observation group and 75.0% in the control group， with the observation group significantly higher than the control group （P < 0.05）.ConclusionModified Xugu Huoxue Decoction can enhance mineralized osteogenesis in the tibial bone transport area， promote callus growth， increase BMD， accelerate postoperative healing， and facilitate recovery of limb function.  
    关键词：fractures;bone transport;tibial bone defects;bone mineral density   
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    更新时间：2026-04-01

    LIU Yuan, LIAO Rong, HE Liuji, WU Xuzhou, LIANG Funing, CAI Yu, WEI Guikang

    Vol. 45, Issue 1, Pages: 11-15(2026) DOI: 10.16025/j.1674-1307.2026.01.003
    摘要：ObjectiveTo observe the clinical efficacy of ear acupoint pressing with beans combined with WEI Guikang's three-dimensional manipulation of the meridians， tendons， and bones in the treatment of knee osteoarthritis （KOA）.MethodsSixty KOA patients admitted to the Ren'ai Branch of the First Affiliated Hospital of Guangxi University of Chinese Medicine from January to December 2023 were enrolled and randomly assigned into an observation group and a control group （30 patients each） according to a random number table. The control group received WEI Guikang's three-dimensional manipulation treatment alone， while the observation group received the same manipulation combined with ear acupoint pressing with beans for 4 consecutive weeks. Before and after treatment， joint dysfunction was assessed using the Lequesne functional index. Knee function was evaluated with the Western Ontario and McMaster Universities Osteoarthritis Index （WOMAC）. Pain was assessed using the Visual Analog Scale （VAS）. Knee function and stability were evaluated with the Lysholm score. Standing and walking ability was assessed using the Timed Up and Go Test （TUGT）. Balance was measured with the Berg Balance Scale （BBS）. Lower-limb muscle strength and dynamic balance were evaluated using the Five Times Sit-to-Stand Test （FTSST）. Safety and clinical efficacy during treatment were compared between the two groups.ResultsAfter treatment， VAS， WOMAC， and Lequesne scores decreased and Lysholm scores increased in both groups compared with baseline （both P < 0.05）. The observation group showed greater improvement than the control group （P < 0.05）. FTSST and TUGT scores decreased， and BBS scores increased in both groups after treatment （both P < 0.05）. The observation group improved more than the control group （P < 0.05）. At 4， 8， and 12 weeks post-treatment， the observation group had a higher total effective rate than the control group （P < 0.05）. No significant adverse reactions occurred in either group during treatment.ConclusionEar acupoint pressing with beans combined with WEI Guikang's three-dimensional manipulation of the meridians， tendons， and bones provides a lasting therapeutic effect in patients with KOA.  
    关键词：Ear acupoint pressing with bean therapy;WEI Guikang;three-dimensional manipulation of the meridians， tendons， and bones;knee osteoarthritis   
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    更新时间：2026-04-01

    WANG Xiaorui, XIA Ruiqi, LIU Yitao, WU Yingying, CHEN Hui, FENG Wei

    Vol. 45, Issue 1, Pages: 16-21(2026) DOI: 10.16025/j.1674-1307.2026.01.004
    摘要：ObjectiveTo evaluate and compare the efficacy of nasal irrigation with Jiawei Yupingfeng and saline combined with nasal corticosteroids in the treatment of rhinitis medicamentosa.MethodsA prospective controlled study was conducted at Wangjing Hospital of China Academy of Traditional Chinese Medicine from September 2023 to December 2024. The study included 84 patients diagnosed with Rhinitis medicamentosa and treated during this period. Patients were randomly divided into two groups： a saline rinse group and a traditional Chinese medicine rinse group. The randomization method used was a numerical table method. The saline rinse group was treated with saline nasal irrigation combined with nasal corticosteroids， while the traditional Chinese medicine rinse group was treated with Jiawei Yupingfeng nasal irrigation combined with nasal corticosteroids. The patients were followed up for a period of one month. The patients in the Chinese medicine rinsing group underwent a 2-week course of nasal irrigation with Jiawei yupingfeng in conjunction with nasal corticosteroids， followed by a 3-month follow-up period. The Visual Analog Scale of Nasal Congestion （VAS）， the Nasal Resistive Index （NRI）， the Nasal Acoustic Reflex （NAR）， and the sinuses outcome test-20（SNOT-20） were compared and analyzed before and after treatment for the two groups.ResultsThe total effective rate of treatment in the Chinese medicine flushing group （92.7%） was higher than that in the saline flushing group （76.2%）， and the difference was statistically significant （P < 0.05）； the rate of decongestant reuse in the Chinese medicine flushing group （7.7%） was lower than that of decongestant reuse in the saline flushing group （28.1%） and the difference was statistically significant （P < 0.05）； Compared with before treatment， VAS score， SNOT-20 score and effective resistance of nasal cavity decreased （P<0.05）， and nasal cavity volume increased significantly （P<0.05）. The VAS score of nasal obstruction ，nasal effective resistance and nasal volume 0-7cm from nostril were not significantly different between the two groups before treatment （P>0.05）. After treatment， the VAS score of nasal obstruction，the SNOT-20 score， nasal effective resistance in the Chinese medicine irrigation group were significantly lower than those in the saline irrigation group （P<0.05）， and nasal volume 0-7cm from nostril in the Chinese medicine irrigation group was significantly higher than that in the saline irrigation group （P<0.05）.ConclusionJiawei Yupingfeng nasal irrigation combined with nasal corticosteroids therapy is better than saline nasal irrigation combined with Nasal corticosteroids therapy， which significantly reduced the patients' dependence on decongestants and significantly improved their quality of life.  
    关键词：Jiawei Yupingfeng;rhinitis medicamentosa;nasal irrigation;nasal corticosteroids   
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    更新时间：2026-04-01

    ZHU Limeina, LU Songzhang, JIA Li

    Vol. 45, Issue 1, Pages: 22-25(2026) DOI: 10.16025/j.1674-1307.2026.01.005
    摘要：ObjectiveTo investigate the incidence of the female triad and the types of traditional Chinese medicine （TCM） constitution in patients with oral lichen planus （OLP）， providing a basis for treating OLP with the methods of promoting qi circulation， activating blood， and resolving phlegm to disperse nodules， and to promote early screening and diagnosis of the female triad in OLP patients.MethodsA total of 187 female patients with OLP who visited the Department of Stomatology at Guang'anmen Hospital， China Academy of Chinese Medical Sciences from January 2024 to December 2024 were enrolled and assigned to the observation group. During the same period， 160 female patients with other stomatological diseases were assigned to the control group. The incidence of nodules and the types of TCM constitution were compared and analyzed between the two groups.ResultsThe incidence of thyroid nodules， breast nodules or hyperplasia， uterine fibroids， and the female triad in the observation group was higher than in the control group （P < 0.05）. The incidence of multiple nodules or hyperplastic lesions was also higher in the observation group （P < 0.05）. Among the observation group， the incidence of the female triad in patients with erosive OLP was 28.6%， and in patients with non-erosive OLP was 34.4%； the difference was not statistically significant （P > 0.05）. The proportions of qi-stagnation， phlegm-dampness， and blood-stasis constitutions were higher in the observation group than in the control group （P < 0.05）.ConclusionPatients with OLP have a higher incidence of thyroid nodules， breast hyperplasia， uterine fibroids， and the female triad， and their TCM constitutions are predominantly qi-stagnation， phlegm-dampness， and blood-stasis.  
    关键词：oral lichen planus;female triad;TCM constitution;Treating different diseases with same method   
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    更新时间：2026-04-01

    GUO Ziyun, DU Lina, QIU Mengyao, XIE Xiaoxuan, YANG Yan

    Vol. 45, Issue 1, Pages: 26-29(2026) DOI: 10.16025/j.1674-1307.2026.01.006
    摘要：ObjectiveTo explore the distribution characteristics of disease onset across solar terms in three syndrome types of infantile cytomegalovirus hepatitis， and to provide a theoretical basis for disease prevention and management from the perspectives of chronomedicine and the theory of correspondence between humans and nature.MethodsA total of 360 infants with cytomegalovirus hepatitis who visited the Department of Traditional Chinese Medicine at Beijing Children’s Hospital， Capital Medical University， from January 2019 to February 2024 were enrolled. According to traditional Chinese medicine （TCM） syndrome differentiation， the patients were divided into three groups： dampness-heat internal accumulation syndrome， spleen deficiency with dampness retention syndrome， and qi stagnation with blood stasis syndrome， with 120 cases in each group. Based on the dates of disease onset， frequency analysis and line charts were used to statistically analyze the seasonal and solar-term distributions of onset among different syndrome types.ResultsThe onset of infantile cytomegalovirus hepatitis was mainly concentrated in winter and spring， with solar terms predominantly occurring during Chunfen （Spring Equinox）， Qingming （Pure Brightness）， Guyu （Grain Rain）， Xiaohan （Slight Cold）， and Dahan （Great Cold）. In the dampness-heat internal accumulation syndrome group， onset was mainly concentrated in spring and summer， with Qingming， Guyu， Xiazhi （Summer Solstice）， Xiaoshu （Slight Heat）， and Dashu （Great Heat） being the most common solar terms. In the spleen deficiency with dampness retention syndrome group， onset occurred mainly in spring and winter， with Qingming， Guyu， Xiaohan， and Dahan being predominant. In the qi stagnation with blood stasis syndrome group， onset was also mainly concentrated in spring and winter， with Lichun （Beginning of Spring）， Jingzhe （Waking of Insects）， Chunfen， Xiaohan， and Dahan being the most common solar terms.ConclusionThe onset of infantile cytomegalovirus hepatitis in the three syndrome types shows distinct seasonal and solar-term distribution characteristics.  
    关键词：infantile cytomegalovirus hepatitis;24 solar terms;chronomedicine;correspondence between humans and nature;dampness-heat internal accumulation;spleen-deficiency with dampness retention;qi stagnation with blood stasis   
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    更新时间：2026-04-01
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