摘要:Objective To investigate the clinical effects of dual therapy and triple therapy on sequelae of pelvic inflammatory disease( SPID) of cold-damp stagnation type. Methods 120 patients who met the diagnostic criteria of SPID of cold-damp stagnation type were randomly divided into 2 groups. Two groups were respectively given dual therapy( oral taking and enema of Chinese herbal medicines)and triple therapy( oral taking and enema of Chinese herbal medicines plus infrared light therapy). The changes of symptoms and signs,the clinical effects and safety index of both groups were observed and local sign scores and TCM syndrome scores were evaluated before and after 2 months of treatment. Results The total improvement rate of triple therapy group was 68. 33%, TCM syndrome improvement rate was 75. 00%, the local sign improvement rate was 66. 67%; while that of dual therapy group was 36. 67%,46. 67%,25. 00% respectively. The differences were statistically significant between the two groups( P < 0. 05). The sign score of both groups were obviously reduced after treatment,but the triple group was lower than the dual group,and the differences the two groups were statistically significant between( P < 0. 05). Conclusion The triple therapy has satisfactory effect on SPID of cold-damp stagnation type in improving the symptoms,local signs and can more obviously increase the clinical recovery rate which shows more positive effects than the dual therapy.
摘要:Objective To observe the clinical effect of retention enema with Chinese herbal medicines combined with colonic dialysis on chronic kidney disease( CKD) at stage III and IV. Methods 90 patients were randomly divided into control group and treatment group,each with 45 cases. All the patients were treated with conventional therapy,while the treatment group was also given retention enema with Chinese herbal medicines combined with colonic dialysis. The clinical symptoms,curative effect,the changes of renal function,uric acid and serum phosphorus of two groups were observed before and after the treatment. Results After treatment,the clinical symptoms,curative effect,renal function,uric acid,and blood phosphorus were significantly improved in both two groups( P < 0. 05,P < 0. 01),and the effect of the treatment group was better than that of the control group( P < 0. 05,P < 0. 01). Conclusion Retention enema with Chinese herbal medicines combined with colonic dialysis is effective for patients with CKD at stage III and IV,and can delay the progress of CKD.
关键词:Colon dialysis;enema with Chinese herbal medicines;CKD;clinical observation
摘要:Objective To discuss the efficacy of abdominal acupuncture on drug-dependent insomnia and establish the theoretical basis for it with clustering analysis. Methods 30 patients of drug-dependent insomnia were treated with abdominal acupuncture,and the pre-and post-treatment results of Pittsburgh Sleep Quality Index( PSQI) and symptom self-evaluation scale( SCL-90) were compared. The data were processed with clustering statistics and dimension reduction analysis to discuss the theoretical foundation for the treatment. Results The pre-/post-differences of PSQI and SCL-90 scores were both statistically significant( P < 0. 05) after four weeks of treatment,with post-treatment scores lowering than that of pre-ones. The items " somatization" on SCL-90 of 14 out of 26 patients turned from positive( pre-) to negative( post-) with T value reducing from 2. 56 to 1. 96. Conclution Somatic symptoms can be greatly improved by abdominal acupuncture after the treatment as the movement of qi and blood could be invigorated and adjusted and the meridian and collateral system could be smoothed.
摘要:Objective To observe the clinical efficacy,quality of life and adverse reactions of Chinese herbal medicine Yiqi Jianpi Prescription combined with S-1 treatment for aged cases of advanced gastric cancer. Methods A total of 85 aged cases with advanced gastric cancer were retrospectively analyzed. These cases were divided into two groups. The control group was treated with S-1 taken orally only,and the observation group was given S-1 and Chinese herbal medicine Yiqi Jianpi Prescription orally; 28 days constituted one course. The patient’ s general condition and hematological indexes were observed and the efficacy evaluated after 4 courses of treatment with one year following-up of survival rate and overall survival time. Results After 4 courses of treatment,Karnofsky scores( KPS) improvement rate of the control group was lower than that of the observation group,and the difference had statistical significance( P < 0. 05). TheⅡ Ⅳ neutrophil decline rate of the control group was higher than that of the observation group,and the difference had statistical significance( P < 0. 05). The difference of digestive tract adverse reactions had no statistical significance between the two groups and the difference had no statistical significance( P > 0. 05). The recent remission rate( CR + PR) of the control group and the observation group were 50. 0% and 58. 5% respectively,and the difference had no statistical significance( P > 0. 05). The one year survival rate between the two groups( 61. 4%,75. 6%) also had no statistical significance( P > 0. 05). Kaplan-Meier survival curve demonstrated that median survival time of the control group was 12. 6 month and that of the observation group was 15. 6 months,and the difference was statically significant( P < 0. 05). Conclusion Chinese Herbal Medicine Yiqi Jianpi Prescription combined with S-1 taken oral could improve the quality of life,reduce the adverse reactions caused by chemotherapy and prolong the overall survival time in aged patients with advanced gastric cancer.
关键词:aged patients;advanced gastric cancer;S-1;Chinese herbal medicine;quality of life
摘要:目的探讨调肝理脾法相关方剂干预腹泻型肠易激综合征(IBS-D)临床疗效。方法计算机检索2009年1月—2017年3月Pub Med、中国期刊全文数据库(CNKI)、中国科技期刊数据库以及万方数字化期刊全文数据库中有关调肝理脾法治疗IBS-D的RCTs,采用Rev Man 5.3软件进行Meta分析。结果纳入16项RCT,共1409例患者。Meta结果显示,调肝理脾法相关方剂干预IBS-D在改善腹痛、腹泻等主要症状、中医证候以及生活质量方面优于西药常规治疗。结论综合考虑纳入RCTs研究方法学质量、较少报道复发率等情况,对上述结果不能过于乐观,中医药防治IBS仍面临挑战。
摘要:目的系统评价醒脑静联合依达拉奉治疗脑出血的临床疗效和安全性与单用依达拉奉是否存在差异,为临床合理用药提供依据。方法计算机检索Pub Med、Embase光盘数据库、Cochrane图书馆、CNKI、VIP、万方数据库、中国生物医学文献数据库,检索时间均限定为建库至2017年8月。收集醒脑静联用依达拉奉治疗脑出血的随机对照研究(RCTs),由两名研究者按照纳入与排除标准独立筛选文献、评价纳入研究的方法学质量并提取资料后,用Rev Man 5.3软件进行Meta分析。结果共纳入15个研究,包括1464例患者。最终分析结果显示,与对照组相比,联合用药能够提高临床疗效[OR=4.18;95%CI:2.906.02],在降低神经功能缺损评分[MD=-5.07,95%CI:-7.01-3.13]和Barthel指数[MD=22.14,95%CI:19.5024.79],提高GCS评分[MD=3.03,95%CI:2.633.42]方面具有一定优势,其差异均有统计学意义(P<0.05);对照组不良反应发生率为6.01%;试验组发生率为5.64%。敏感性分析和漏斗图分析显示纳入的文献未出现影响结果的偏倚。结论目前研究显示醒脑静联合依达拉奉治疗脑出血比单用依达拉奉能提高疗效,有利于神经功能恢复、改善生活质量。安全性无明显差异,还需要进一步探讨。