摘要:Objective To evaluate the clinical efficacy and safety of Cangfu Lotion in treating keratosis eczema of hands and feet externally,which come from the empirical formulas of a famous TCM doctor ZHAO Bing-nan’s. Methods The treatment group of60 cases was treated externally with Cangfu Lotion and white vaseline ointment. The control group of 60 cases was treated with Binghuangfule Ointment. The course of treatment was 4 weeks. The area of skin rash,itching degree and objective index of skin rash were scored every week. The effect was evaluated at the end of the course. Results The total effective rate of the treatment group was 75. 4 %,and the control group was 76. 8 %. There was no statistical difference between the two groups( P > 0. 05).After treatment,the scores of both groups were lower than that before treatment,which were significantly different( P < 0. 05).The scores of keratinization,rhagadia,squama and skin lesion were all lower than that of the control group,and the difference was statistically significant( P < 0. 05). There were no serious adverse reactions in both two groups. Conclusion The clinical effect of Cangfu Lotion in externally treating keratosis eczema of hands and feet is good. It is worthy of clinical application and further development.
关键词:Cangfu Lotion;external treatment of TCM;keratosis eczema
摘要:Objective To study the clinical efficacy of reversing powder combined with dual wavelength laser in the treatment of rosacea of excessive heat in the lung and stomach. Methods 52 patients with rosacea were randomly divided into 2 groups. 27 patients in the treatment group were treated with reversal powder combined with Cynergy dual wavelength laser treatment. The treatment parameters were selected according to the skin types,the thickness and depth of the blood vessel,the degree of erythema,and after the therapeutic purpura disappeared,reversing powder was used externally every day. 25 patients in the control group were treated with Cynergy dual wavelength laser. The course of treatment was 8 weeks. Results The effective rate was 81. 5% in the treatment group and56. 0% in the control group. The difference of effective rate between the two groups was statistically significant( P < 0. 05),and the effective rate of the treatment group was higher than that of the control group. Conclusion reversing powder combined with dual wavelength laser has good clinical efficacy and fewer side effects in the treatment of rosacea of excessive heat in the lung and stomach.
摘要:目的评价干扰素(IFN)联合黄芪注射液(AI)治疗小儿病毒性心肌炎的临床疗效。方法计算机检索Cochrane图书馆、Pub Med、EMbase、Medline、CNKI、VIP、万方数据库中关于比较干扰素联合黄芪注射液加西医常规治疗(以下简称"试验组")与西医常规治疗(以下简称"对照组")小儿病毒性心肌炎的随机对照试验,时间均为建库至2017年3月。对符合纳入标准的随机对照试验采用Rev Man 5.3软件进行Meta分析,用森林图表示Meta分析结果。计量资料采用均数±标准差(x珋±s)表示,计数资料采用频数、率、比(%)表示。结果共纳入16个研究,1336例患者。Meta分析结果显示,试验组治疗小儿病毒性心肌炎总有效率优于对照组[OR=6.60,95%CI(4.35,10.01),P<0.01];治疗后,试验组CK水平较对照组低[SMD=-0.97,95%CI(-1.57,-0.37),P=0.002]、试验组CK-MB水平较对照组低[SMD=-1.07,95%CI(-1.58,-0.57),P<0.01]、试验组LDH水平较对照组低[SMD=-0.94,95%CI(-1.47,-0.41),P=0.0005];治疗后试验组心电图恢复时间较对照组短[SMD=-3.28,95%CI(-4.36,-2.20),P<0.01]。结论病毒性心肌炎患儿在西药常规治疗下使用干扰素联合黄芪注射液可明显改善临床疗效和症状。
摘要:目的系统评价麝香保心丸治疗高脂血症的疗效及安全性。方法计算机检索Cochrane图书馆、Pub Med、Embase、CNKI、CBM、VIP、万方数据库,纳入相关RCT,并进行评价,采用Rev Man 5.3软件分析数据。结果纳入8篇RCTs共715例。相比对照组,麝香保心丸的心绞痛疗效较高[RR=1.20,95%CI(1.08,1.33),P=0.0008]。治疗后总胆固醇水平低于对照组[WMD=-0.56,95%CI(-0.88,-0.23),P<0.00001]。治疗后甘油三酯水平低于对照组[WMD=-0.26,95%CI(-0.37,-0.15),P<0.00001]。治疗后高密度脂蛋白水平与对照组相比差异无统计学意义[WMD=0.04,95%CI(-0.06,0.15],P=0.42]。治疗后低密度脂蛋白水平低于对照组[WMD=-0.28,95%CI(-0.51,-0.04),P=0.02]。各项研究均未报道不良反应案例。结论本文认为麝香保心丸治疗心绞痛疗效明显。对TC、TG、LDL-C改善整体有效,与常规治疗相比效果显著,但联合他汀类药物与单独使用他汀类药物相比差异未见统计学意义,对HDL-C的疗效仍需更多文献证明。推荐临床应用于冠心病合并高脂血症的治疗,并建议补充更多高质量的相关研究。