最新刊期
期 10 ， 2019
- 摘要：目的基于中医传承辅助系统软件,总结赵炳南教授外治方药的临床用药特点。方法选取《赵炳南临床经验集》收录的137个病案的148张外治处方,输入系统,采用关联规则阿Apriori算法、复杂系统熵聚类等无监督数据挖掘方法,分析赵炳南教授治疗皮外科疾病外治方药运用特点。结果赵教授应用外治方药治疗皮外科疾患的用药以清热解毒、活血散结为主。结论处方整体与湿毒蕴结辨证较为契合,体现了赵教授独特的辨治体系和用药特色,为进一步研究和挖掘提供了参考。关键词：赵炳南;外治方药;数据分析
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发布时间：2023-05-12 - 摘要：赵炳南教授在传统中医外治临方调配基础上,对临方调配方剂、方法、辅料进一步研究,常用油剂如甘草油、紫草油、蛋黄油等;继承润肌膏又创赵氏清凉（爽）膏,并衍生祛湿药膏、黄连软膏、阴蚀黄连膏、白蔹膏、苦参膏、复方化毒膏,均为油蜡药面膏制剂;古方软膏丰富,赵老尤善临方调配普连膏（芩柏膏）、普榆膏、紫色消肿膏,效果极佳。王萍教授承袭赵老经验,带领北京中医医院皮肤科深入钻研,在介质及用药方面不断尝试,对老专家经验遵循"师古创新"的治学思想,坚持中医外治辨证论治与临证配药,不断提高中医诊治皮肤病水平。关键词：中药外治;赵炳南;经验;临方调配
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发布时间：2023-05-12 - 摘要：赵炳南先生经验外洗方苍肤洗剂源自止痒杀虫汤、蛇床子汤、苦参汤等,为赵老外用代表性方剂,具有燥湿润肤、杀虫止痒功效。临床适用于慢性湿疹、手足癣、掌跖角化以及其他肥厚性、角化性皮肤病等一系列因湿邪留滞经络,气机升降失常,导致的顽固性皮肤病,即"湿滞"性皮肤病。化裁应用灵活,配伍黄柏、土大黄、芒硝加强燥湿止痒之力,配伍当归、首乌藤、桃仁等能养血润肤,配伍黄柏、花椒、白蒺藜等可燥湿祛风止痒,配伍板蓝根、蒲公英等能清热解毒,本文特举典型病案予以说明。关键词：苍肤洗剂;赵炳南;外洗方;湿滞;临证发挥
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发布时间：2023-05-12 - 摘要：赵炳南先生在中医皮外科领域具有举足轻重的地位,为我国中医皮肤科的发展贡献了毕生心血,对于瘢痕疙瘩的中医病名认识方面,赵老认为依据形态,命名瘢痕疙瘩为"锯痕症"更为直观形象,认为其病因病机主要为气机失调,气滞血凝;赵老对于黑布药膏的组方用药十分精准周到,既选药力专,又兼顾药物外用剂型所需;强调黑布药膏在使用中的正确方法及注意事项也十分重要。黑布药膏治疗瘢痕疙瘩的现代基础研究为其临床疗效提供了实验学证据。关键词：赵炳南;特色疗法;黑布药膏;瘢痕疙瘩
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发布时间：2023-05-12 - 摘要：<正>2016年2月26日,国务院印发了《中医药发展战略规划纲要（2016-2030年）》[1],明确了未来我国中医药发展方向和工作重点,提出到2020年,实现人人基本享有中医药服务。中医护理是中医药服务重要的组成部分,中医护理技术是中医护关键词：中医护理技术;应用现状;展望;述评
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发布时间：2023-05-12 -
Intervention effect of Shang tones of five tones on sedation in patients with mechanical ventilation
摘要：Objective To observe the sedative effect of Shang tones music of five tones for patients with mechanical ventilation.Methods 60 patients who were admitted to the ICU of our hospital from December 2016 to March 2019 were randomly divided into experimental group of 31 cases and control group of 29 cases.The control group was given with conventional sedation treatment,that is,sedative drug（midazolam）was used according to the doctor’s prescription,while the experimental group was also intervened with Shang tones music therapy on the basis of conventional sedation treatment.The research period was from 3 to 14 days.The research ended when the patient was pulled out of the endotracheal tube,or discharged from the hospital or transferred to another hospital,and dead.RASS scale for sedation was used to evaluate the sedative condition at 7∶00 and 17∶30 everyday.The dosage,duration,intubation time and extubation rate of sedatives were compared between the two groups.Results There was no statistical significance in RASS scale everyday between the two groups（P>0.05）.The dosage of sedatives used on day 7 in the observation group was less than that in the control group,the time of using sedatives was also less（P<0.05）,the intubation time was shorter,and the extubation rate was higher（P<0.05）.Conclusion The Shang tones music therapy can reduce the dosage and time of sedative drugs for the patients with mechanical ventilation,and can also shorten the intubation time and improve the extubation rate of these patients.关键词：music therapy;Shang tones;mechanical ventilation;calm- 2
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发布时间：2023-05-12 - 摘要：Objective To observe the effect of medicinal pillow combined with auricular acupoint pressing in relieving perioperative anxiety and depression of patients with gastrointestinal malignancy.Methods 120 patients with anxiety and depression on admission,who would undergo surgery for gastrointestinal malignancy at appropriate time,were randomly divided into emotional care group,medicinal pillow group,auricular point pressing group,medicinal pillow combined with auricular point pressing group with 30 cases in each group.Emotional nursing group was given the emotional nursing measurements according to TCM nursing plan; the medicinal pillow group was treated with Chinese herbal medicine pillow on the basis of the treatment given to the emotional nursing group;the auricular point pressing group combined auricular point pressing treatment together with the treatment for the emotional care group;on the basis of the treatment for the emotional nursing group,the combination of TCM pillow and auricular point pressing therapy was added to the medicinal pillow combined with auricular point pressing group.Anxiety self-rating scale（SAS）and depression self-rating scale（SDS）were used to evaluate the effect of intervention on admission and when discharged from the hospital.Results The SAS scores and SDS scores of the four groups of patients when discharged were significantly lowered than those on admission,all the differences were statistically significant（P<0.01）.The SAS scores and SDS scores of patients in the medicinal pillow group and ear acupoint pressing group were lower than those in the emotional care group when discharged,and the differences were statistically significant（P<0.01）;there was no statistically significant difference in SAS scores between these two groups（P>0.05）;SDS scores of patients in the medicinal pillow group were lower than those in the auricular acupoint pressing group upon discharge,and the difference was statistically significant（P<0.05）;the SAS score and SDS score of the patients in the combination of medicine pillow and auricular point sticking pressure group were lower than those in the emotional care group,medicinal pillow group and auricular point pressing group when discharged,and the difference was statistically significant（P<0.05）.Conclusion The combination of medicinal pillow and auricular point pressing can effectively relieve the perioperative anxiety and depression of patients with gastrointestinal malignancy,and the effect is better than that of emotional nursing group,medicinal pillow group and auricular point pressing group.关键词：Medicinal pillow;auricular acupoint pressing;gastric cancer;psychological nursing
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发布时间：2023-05-12 - 摘要：Objective To explore the effect of electroacupuncture stimulation combined with percutaneous penetration therapy on chemotherapy-induced nausea and vomiting and its effect on functional living index-emesis after chemotherapy in patients with malignant tumor.Methods Seventy-two patients with malignant tumor received chemotherapy with DDP were randomly divided into experimental group（n=36）and control group（n=36）.The control group were given routine prophylactic antiemetic drugs.The experimental group was treated with electroacupuncture stimulation on Qūchí（曲池LI11）,Nèiguān（内关PC6）,and Zúsānlǐ（足三里ST36）bilaterally and percutaneous penetration therapy（point application）on the basis of control group.The R-INVR scores on the 1 st,2 nd,3 rd day after chemotherapy and FLIE scores on the 1 st and 6 th day after chemotherapy were evaluated.Results 2 cases in the experimental group withdrew their informed consent and 4 cases of shedding cases in control group.Finally,there were 34 cases in the experimental group and 32 cases in the control group,totally 66 cases.There was no significant difference in the general demographic characteristics and clinical baseline data between the two groups（P>0.05）.Comparing the frequency of nausea between the two groups,there was significant difference between the two groups（P<0.05）at day 2（P=0.005）and day 3（P=0.000）.Comparing the duration of nausea between the two groups,there was significant difference between the two groups（P<0.05）at day 3（P =0.000）.Comparing the severity of nausea between the two groups,there was significant difference between the two groups（P<0.05）at day 1（P=0.047）and day 2（P=0.000）and day 3（P= 0.000）.Comparing the frequency of retching,the volume of vomiting and the severity of vomiting between the two groups,there was significant difference between the two groups（P<0.05）at day 3（P=0.000）.Comparing the frequency and severity of retching between the two groups,there was significant difference between the two groups（P<0.05）at day 2（P = 0.002）and day 3（P=0.000）.Comparing the living function index-emesis between the two groups at day 1 an day 6,there was no significant difference at day 1（P=0.618）（P>0.05）and but is significant at day 6（P=0.000）（P<0.05）.Conclusion Electroacupuncture stimulation combined with percutaneous penetration therapy can effectively relieve nausea,vomiting,retching reaction and improve the living function of patients with malignant tumor at the delayed stage after chemotherapy.However,it had no obvious effect on relieving acute nausea,vomiting and retching after chemotherapy,and could not also completely eliminate the negative effects of CINV on the patients.关键词：electroacupuncture;percutaneous penetration therapy;malignant tumor;chemotherapy-induced nausea and vomiting（CINV）;functional Living Index-Emesis（FLIE）
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发布时间：2023-05-12 - 摘要：Objective To evaluate the effect of combined TCM fumigation and auricular point sticking pressure on diabetic skin pruritus.Methods 187 diabetic patients with skin pruritus selected from April 2017 to January 2019 were randomly divided into three groups.60 cases were assigned to the TCM fumigation group who received conventional nursing and TCM fumigation,64 cases were assigned to the auricular point pressing group who received conventional nursing and auricular pressure,and 63 cases were assigned to the combined group who were given conventional nursing,TCM fumigation and auricular pressure.The intervention course was 7 days for all diabetic patients.The changes of Modified Duo’s VAG Scale before and after the intervention of 3 groups were compared.Results The differences of nursing intervention effect of the TCM fumigation group,auricular point pressing pressure group and combined group were statistically significant（P<0.01）.Pairwise comparison of nursing intervention effect showed that the intervention effect of TCM fumigation combined with auricular point pressing was better than that of TCM fumigation group and the auricular point pressing group,and the difference was statistically significant（P<0.01）.Conclusion TCM fumigation combined with auricular point pressing can relieve itching of diabetic patients,and the effect of combined TCM fumigation group and auricular point pressing is better than single use of these two Methods.关键词：TCM fumigation;auricular point pressing;diabetes;pruritus
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发布时间：2023-05-12 - 摘要：目的基于文献,总结耳穴疗法干预卒中后抑郁临床应用规律,为临床治疗规律总结提供参考。方法检索中国知网、中文科技期刊全文数据库、万方数据库、中国生物医学文献数据库、百度学术、中国期刊全文数据库有关耳穴疗法干预卒中后抑郁的临床研究文献,应用频数统计进行分析。结果最终纳入文献37篇,耳穴刺激方法以贴压法为主,联合干预方法针刺、中药汤剂、情志护理、头针和电针最为多见;共涉及耳穴17个,应用频次较高的耳穴依次为心、神门、肝、肾、皮质下,辨证取穴使用率较低,高频次证型依次为气郁化火、心脾两虚和阴虚火旺;耳穴贴压按压频率最常见为2次/d,更换耳贴频率最常见为2 d,干预时间以4周最为多见;观察指标中应用最多的为汉密尔顿抑郁量表（HAMD）、中医证候积分、神经功能缺损量表（NHISS）。结论耳穴疗法干预卒中后抑郁研究尚不充分,临床研究中应关注除贴压法外其他耳穴刺激方法的疗效,大力提高护理人员辨证施护水平,延长临床干预时间,增加客观评价指标的应用,为耳穴疗法干预卒中后抑郁临床应用提供参考。关键词：耳穴疗法;卒中后抑郁;临床研究;文献分析
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发布时间：2023-05-12 - 摘要：目的将中药热熨敷技术应用于肿瘤症状护理并细化关键技术操作环节,提升中医肿瘤专科护理质量。方法成立多学科临床实践小组,通过文献检索、专家论证、临床实践及数据分析,进行症状遴选,以及温度、手法、介质等方面的细化研究。结果将细化后的中药热熨敷技术应用于肿瘤常见症状干预,其中癌因性疲乏185例,癌性疼痛97例,癌症腹胀60例,合计342例。护理有效率分别为88.1%、93.8%、85.0%,患者满意度及依从性均为100%,无烫伤等不良事件发生。结论细化后的中药热熨敷技术,对肿瘤患者常见症状护理具有良好的护理效果,患者满意度高且依从性好。关键词：中药热熨敷;肿瘤症状护理;实践研究
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发布时间：2023-05-12 - 摘要：<正>随着时间医学的发展,中医时间医学的代表——子午流注理论引起国内外学者的广泛关注。中医历代医家均强调"天人相应、天人合一"的整体观念,《灵枢经·岁露论》曰:"人与天地相参也,与日月相应也。"这与西方医学生命与时间关键词：子午流注;中医护理技术;时间医学
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发布时间：2023-05-12 - 摘要：目的观察虎符铜砭刮痧疗法治疗肝火亢盛型高血压的临床效果。方法选择2018年1月—2018年12月河南中医药大学第一附属医院门诊及体检中心初诊为肝火亢盛型高血压患者80例,就诊先后顺序对应的随机卡随机分为对照组和观察组2组,各40例。对照组给予高血压健康教育方案干预,观察组在对照组基础上配合虎符铜砭刮痧疗法,2次刮痧间隔时间为7 d（上次痧印需消退）,共治疗10次。对比2组疗效;对比2组治疗前后24 h动态血压变化,包括24 h平均收缩压、24 h平均舒张压;治疗前后统计患者的中医证候积分。结果观察组降压疗效、中医证候积分改善疗效高于对照组（P<0.05）。治疗后,2组24 h平均收缩压、24 h平均舒张压均较治疗前降低（P<0.01）。与对照组相比,治疗后观察组24 h平均收缩压低（P<0.01）;2组治疗后24 h平均舒张压下相比差异无统计学意义（P>0.05）。治疗后,2组中医证候积分较治疗前降低（P<0.01）。与对照组相比,治疗后观察组中医证候积分低（P<0.01）。结论虎符铜砭刮痧联合健康教育可降低初诊为肝火亢盛型高血压患者的血压,改善临床症状。关键词：肝火亢盛;高血压;虎符铜砭;刮痧;健康教育
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发布时间：2023-05-12 - 摘要：Objective To investigate the effect of Jianpi Bushen Yifei Formula on improving airflow limitation of rats with chronic obstructive pulmonary disease（COPD）by detecting COX-2 and p38 MAPK protein in lung tissue,and study its mechanism.Methods 40 Wistar rats were randomly divided into 4 groups（n=10 each）:normal group,model group（COPD rat model established）,COX-2 inhibitor group（COPD model rats receiving celecoxib 10 mgokg-1 od-1）and Jianpi Bushen Yifei Formula group（COPD model rats receiving Jianpi Bushen Yifei Formula 25.2 gokg-1 od-1）.The FEV0.3,FVC,PEF and MMEF in each group were determined.The expression level of COX-2 and p38 MAPK protein in lung tissue were detected by immunohistochemistry.Results Significant decrease of FEV0.3,FEV0.3/FVC,PEF and MMEF were found in model group,COX-2 inhibitor group and Jianpi Bushen Yifei Formula group when compared with normal group（P<0.01）; FEV0.3,FEV0.3/FVC,PEF and MMEF of COX-2 inhibitor group and Jianpi Bushen Yifei Formula group were significantly improved when compared with model group（P<0.01）; MMEF in Jianpi Bushen Yifei Formula group was significantly improved when compared with COX-2 inhibitor group（P<0.05）.The expression of COX-2 and p38 MAPK in model group,COX-2 inhibitor group and Jianpi Bushen Yifei Formula group were significantly increased compared with normal group（P<0.01 or P<0.05）; The expression of COX-2 in COX-2 inhibitor group and Jianpi Bushen Yifei Formula group were significantly decreased compared with model group（P<0.01）; the expression of p38 MAPK in Jianpi Bushen Yifei Formula group were significantly lowered than model group and COX-2 inhibitor group.Conclusion Jianpi Bushen Yifei Formula can improve airflow restriction by inhibiting COX-2 expression in COPD rats,which may be related to down-regulation of p38 MAPK expression.关键词：Jianpi Bushen Yifei Formula;airflow limitation;COX-2;p38MAPK
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发布时间：2023-05-12 - 摘要：Objective To investigate the therapeutic effect of astragaloside on intrauterine membrane inflammation model of rabbits.Methods Rabbits’ intrauterine membrane inflammation model were instructed,the effects of different doses of astragaloside on rabbit blood routine were observed,histopathological examination were carried out,and protein expression level of CD40 in the endometrial tissue were detected by Western blot.Results Compared with the intrauterine membrane inflammation model group,the total number of monocytes,neutrophils and lymphocytes were decreased after treated by astragaloside,the difference was statistically significant（P<0.05）; histopathological Results showed that with the increase of concentration of astragaloside,the inflammatory cells quantity and infiltration radius in the endometrial tissue were reduced; in addition,astragaloside could lower the protein expression of CD40 in endometrial tissue of intrauterine membrane inflammation model of rabbits.Conclusion Astragaloside has a certain improvement effect on rabbit intrauterine membrane inflammation model,its mechanism may be related to the fact that it can lower protein expression of CD40 in endometrial tissue.关键词：Astragaloside;rabbit;intrauterine membrane inflammation;CD40
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发布时间：2023-05-12 - 摘要：精索静脉曲张（VC）在中青年男性中发病率较高,其中12%～25%患者伴有不育。针对重度VC临床症状明显且伴不育症者可予以手术治疗,精索静脉曲张术后患者精液常规检查改善率可达50%～70%。但VC术后仍有部分患者精液未得到显著改善,郭军教授认为肾虚、血瘀、湿热是精液参数未改善的基本病机,其自拟三藤活络方加减治疗术后精液参数未改善具有显著效果。关键词：精索静脉曲张;男性不育症;郭军;经验继承
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发布时间：2023-05-12 - 摘要：肺癌咳喘多由肺癌及其并发症或治疗不良反应引起,具有病因复杂、程度严重、顽固难愈等特点。杨国旺教授提出运用"病证结合"的诊疗思路治疗肺癌咳喘。肺部肿瘤进展重在短期内缓解症状,宜攻补兼施。肺癌术后状态重在顾护正气,宜补肺健脾。放射性肺炎分期论治,急性期宜清热解毒、养阴生津,慢性纤维化形成期宜活血通络,纤维化期宜滋阴扶阳,重在处理热毒、阴伤与血瘀的矛盾关系。合并阻塞性肺炎宜清消痰热,急则治其标。恶性胸腔积液重在温化,悬饮早期宜泻肺逐饮,悬饮中期宜攻逐痰饮,悬饮晚期宜益气养阴、温阳利水,注意合用化瘀通络法。关键词：杨国旺;病证结合;肺癌;咳嗽;气喘
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发布时间：2023-05-12 - 摘要：类风湿关节炎（RA）是一种主要以对称性累及手足小关节的慢性多关节炎,是全身性、异质性自身免疫性疾病。孟凤仙教授认为热毒痰浊,湿瘀交织互滞为RA急性期病机特征;寒热错杂,痰瘀胶结,虚实并存为慢性迁延期病机特点;正气不足,阴阳俱损,伏邪久留为晚期共性病候。治疗注重整体观念,攻补兼施,擅长使用藤类药及虫类药,并针对RA急性期热毒瘀滞证创立"藤莓汤"。关键词：孟凤仙;类风湿关节炎;辨证论治;老中医
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发布时间：2023-05-12 - 摘要：张秋云教授认为功能性便秘为虚实夹杂之证,病位主要在大肠,与脾、胃、肺脏腑功能失调有密切联系,病机为脾肺气虚,胃肠气滞。脾胃升降失常是功能性便秘发病的病理基础,肺肠宣降失宜是该病发生的重要因素。因此,在临证治疗中,不可过度攻伐,应补通兼顾,宜采用健脾理肺通便之法;强调健运脾胃,宣畅肺气,从而达到恢复大肠传导功能的目的;用药平和,注重补中有通,补而不滞,通而有度,补虚泻实,标本兼顾,临床收效显著。关键词：张秋云;功能性便秘;健脾理肺
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发布时间：2023-05-12 - 摘要：越婢加术汤出自《金匮要略》,清热生津以治水。临床应用越婢加术汤应明辨患者"虚劳"体质,证治不应拘于泌尿系统及免疫系统疾病。临床取效有3个关键点:一是抓住主要方证与方证鉴别,越婢加术汤的方证是湿热之水肿或湿疹,皮肤局部色红瘙痒,汗多,双下肢无力,面色偏黄,纳差,脉沉,其主要方证是湿热之水肿或湿疹,双下肢无力;二是临证运用此方需明确麻黄与石膏不同配伍比例的药效,并且对于湿邪较重的患者应当用苍术代替白术则疗效更佳;三是按照类方加减以及经方叠用拓展越婢加术汤的证治范围。若兼见腰重而冷痛、腰部时有水肿、尿频、尿失禁者可合用甘草干姜茯苓白术汤,若兼见胸腔积液、夜间不能平卧或夜间时有憋醒、胸满胀、面部浮肿、全身倦怠感、咳逆上气、喘鸣塞迫、咳黄稠痰、四肢冷者可合用葶苈大枣泻肺汤。关键词：越婢加术汤;水肿;湿疹;临床经验
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发布时间：2023-05-12 - 摘要：类风湿关节炎是一种以慢性、进行性、侵袭性关节炎为主要表现的全身性自身免疫疾病。病程特点为活动期和缓解期交替出现,各期表现独具特征,分期辨证论治可显著提高针对性。病证结合、分期论治可扼要概括为:早期风寒湿、活动期湿热瘀、缓解期正虚邪实;再结合患者特定情况辨证治疗,可使治疗方案原则性与灵活性兼备。具有较强临床实用性和可操作性,从而提高类风湿关节炎中医临床疗效、改善患者预后。关键词：类风湿关节炎;中医;辨证;病证结合;分期论治
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发布时间：2023-05-12 - 摘要：阳气亏虚、阴邪阻滞是胸痹的基本病机。以该病机为指导辨治胸痹是常规经典治疗思路。温病学家以擅治温病闻名,考虑胸痹阳气亏虚、阴邪阻滞的病机,温病学家似于胸痹并无特色。然而《临证指南医案》亦收录了叶天士治疗胸痹的医案,值得探讨研究。本文基于《临证指南医案·胸痹》14则胸痹医案,以治法为切入点和整理主线,解析叶氏治疗胸痹医案,将叶天士治疗胸痹的治法总结为法仲景,辛滑温通;宣肺卫,苦辛开郁;运中焦,调和升降及通血络,蠲痹止痛等四法。同时,叶天士注意到了胸痹病机演变中有热证,痹久具有向肺痈肺痿转化之机,此时用药多辛苦润,该病机演变尚需深入研究及阐释。关键词：临证指南医案;胸痹;叶天士
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发布时间：2023-05-12 - 摘要：目的观察桂枝茯苓胶囊对子宫内膜异位症术后患者痛经和血清CA125水平的影响。方法选择2014年1月—2016年12月在浙江省慈溪市妇幼保健院妇科进行腹腔镜手术的子宫内膜异位症患者84例,术后患者随机分为对照组和观察组,每组42例。2组患者均予术后第1次月经来潮第5天起服用米非司酮25 mg/次,1次/d,连服3个月;观察组在对照组基础上加服桂枝茯苓胶囊,连续用药3个月后,比较2组临床疗效、疼痛程度VAS评分和血清CA125水平变化。术后随访12个月,比较2组复发及妊娠情况。结果观察组总有效率明显高于对照组（P<0.05）。治疗前,2组VAS评分和血清CA125水平比较,差异无统计学意义（P>0.05）;治疗后,观察组VAS评分和血清CA125水平明显低于对照组,差异均有统计学意义（P<0.01）。随访12个月,观察组复发率低于对照组（P<0.05）,受孕率高于对照组（P<0.05）。结论桂枝茯苓胶囊治疗子宫内膜异位症术后患者疗效确切,可以降低患者痛经程度和复发率、提高受孕率,其作用机制可能与降低患者血清CA125水平有关。关键词：桂枝茯苓胶囊;子宫内膜异位症;肿瘤相关抗原125
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发布时间：2023-05-12 - 摘要：目的观察参芪地黄汤对血清抗磷酯酶A2受体（PLA2R）抗体（+）的特发性膜性肾病气阴两虚型患者的临床疗效。方法将62例拒绝应用激素及免疫抑制剂治疗的特发性膜性肾病气阴两虚型患者分为观察组34例及对照组28例,对照组应用血管紧张素转化酶抑制剂（ACEI）/血管紧张素II受体阻滞剂（ARB）治疗,观察组在对照组治疗基础上应用参芪地黄汤为主方中药汤剂口服治疗,分别于治疗前及治疗8、16、24周后观察2组PLA2R抗体滴度、24 h尿蛋白定量、血清白蛋白（ALB）水平及中医症状评分等指标。结果治疗8、16、24周后,2组血清PLA2R抗体滴度、24 h尿蛋白定量水平及中医症状评分呈下降趋势,ALB水平呈上升趋势。观察组治疗16、24周后24 h尿蛋白定量及中医症状评分较对照组低,差异有统计学意义（P<0.05）;治疗24周后ALB水平较对照组高,差异有统计学意义（P<0.05）;治疗8、16、24周后血清PLA2R抗体滴度均低于对照组,差异均有统计学意义（均P<0.05）。观察组治疗8、16、24周后膜性肾病疗效分别为46.88%、59.38%、81.25%,对照组为38.46%、26.92%、53.85%,16、24周后2组间差异有统计学意义（P<0.05）;观察组治疗8、16、24周后中医证候疗效分别为56.25%、81.25%、90.63%,对照组为38.46%、53.84%、69.23%,2组间差异有统计学意义（P<0.05）。结论参芪地黄汤对于特发性膜性肾病气阴两虚型有较明显疗效,血清PLA2R抗体下降可作为临床疗效预测指标。关键词：参芪地黄汤;气阴两虚;特发性膜性肾病;血清抗磷酯酶A2受体
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发布时间：2023-05-12 - 摘要：目的比较通调三焦理论的中药治疗方案与传统幽门螺杆菌（Hp）根除疗法治疗慢性胃炎Hp阳性的疗效。方法观察组给予金宇安主任通调三焦法所拟定的方药,对照组采用传统Hp根除疗法方案,分别在治疗前及治疗后采用Hp清除率以及症状评分对患者进行评定,观察2组患者Hp根除率,以及症状评分的改善情况,同时进行综合疗效评价。结果观察组Hp根除率82.76%、对照组Hp根除率85.96%,2组间差异无统计学意义（P>0.05）。2组上腹饱胀感、胃痛、胃灼热感方面症状积分改善,与治疗前比较差异有统计学意义（P<0.05）;观察组改善症状积分改善优于对照组,差异有统计学意义（P<0.05）。结论通调三焦法中药在根除Hp方面疗效与传统西药方案等效,在改善主观症状方面更具优势。关键词：慢性胃炎;幽门螺杆菌;中医治疗;金宇安
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发布时间：2023-05-12 - 摘要：<正>糖尿病肾病是临床常见的糖尿病主要微血管并发症之一,其基本病理改变为肾小球系膜基质增生、肾小球毛细血管基底膜增厚与肾小球硬化[1],逐渐发展为肾小球、肾小管间质纤维化,最终导致肾功能衰竭,从而步入透析[2]。其在早关键词：糖尿病肾病;病因病机;辨证论治
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发布时间：2023-05-12 - 摘要：<正>放疗作为腹盆腔恶性肿瘤综合治疗的重要手段之一,对提高局部肿瘤控制率、降低复发转移率意义重大。虽然近些年来放疗精准度在不断提高,但随着腹盆腔恶性肿瘤发病率的提高、放疗技术的普及,放射性肠炎的患病人数也呈现较大关键词：放射性肠炎;中医外治;研究进展
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发布时间：2023-05-12 - 摘要：<正>膝骨关节炎（knee osteoarthritis,KOA）是由多因素共同作用导致膝关节功能和结构损害的慢性病,以关节软骨变形、破坏及骨质增生为特征[1],其在我国的发病率较高且严重影响患者的生活质量,有研究[2]结果显示,我国症状性KOA患者约关键词：膝骨关节炎;影像学;手法;治疗
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发布时间：2023-05-12 - 摘要：<正>姜黄素是中药姜黄的主要成分之一,其在抗新生血管生成方面具有显著作用,本文概括了姜黄素抗新生血管作用的研究进展及相关机制,主要有抑制血管内皮细胞增殖、黏附及迁移,促进血管内皮细胞凋亡,抑制促血管生成因子的表达,同时总结了其在眼科新生血管类疾病的研究应用,关键词：姜黄;姜黄素;抗新生血管;眼科新生血管类疾病
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发布时间：2023-05-12
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