最新刊期

    4 2019
    • Vol. 38, Issue 4, Pages: 307(2019)
      摘要:<正>王鸿士(1919—1985年),主任医师,河北省武清县人,全国名老中医,著名肝病和杂病学专家。王老幼承家技,攻岐黄之术,15岁即随父应诊; 1940年就学于肖龙友、孔伯华共同创办的"北京国医学院",其学术思想深受二位名医影响; 1944年拜前御医瞿文楼为师,随医侍诊,勤学不倦。王老传承名师经验,结合临床实践,形成了独具特色的肝病及疑难杂病诊疗体系。王鸿士一生积极参与中医事业的发展工作,新中国成立初期,响应政府号召,联合中医同仁积极创办北京地区的中医联合诊所,并主持衙门口中医联合诊所工作。1956年北京市卫生局(现北京市卫生健康委员会)牵头组建北京中医医  
        
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      发布时间:2023-04-10
    • LUO Ming-li,QI Tuan-jie,WANG Guo-wei
      Vol. 38, Issue 4, Pages: 307-310(2019) DOI: 10.16025/j.1674-1307.2019.04.001
      摘要:介绍王鸿士对郁证的认识与辨治经验在慢性病毒性肝炎诊疗中的应用。王老认为,郁证是慢性毒性肝炎的常见病理过程,而郁证同时会加重慢性病毒性肝炎的进展,特别是气郁后引发的血郁、痰郁可致痰浊瘀血阻塞肝络,凝聚成形,而成积聚、癥瘕等病变,进而引发肝硬化。故在慢性病毒性肝炎的治疗中应重视郁证的辨识与防治,以调气为根本大法,从气郁、气逆、气虚3个方面进行辨证论治,同时配合心理疏导与运动疗法,全方位诊治,从而提高临床疗效及患者生活质量。  
      关键词:王鸿士;郁证;气郁;调气;慢性病毒性肝炎   
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      发布时间:2023-04-10
    • WU Jing-jing,SUN Feng-xia,MEN Qiu-shuang
      Vol. 38, Issue 4, Pages: 310-312(2019) DOI: 10.16025/j.1674-1307.2019.04.002
      摘要:王鸿士先生借鉴历代医家治疗"黄疸"的理论,结合自己多年的临床实践经验,形成了独特的学术思想和证治理论,尤其对病毒性肝炎所致黄疸的证治有独到的见解。王老强调病毒性肝炎所致黄疸因"伏邪"内郁,阴精阳气失调,导致湿热为患,侵及不同的脏腑经络而发为不同类型。治疗时要辨清湿热侵袭的部位,湿热之轻重以及正邪的盛衰。清利湿热是治疗病毒性肝炎所致黄疸的基本原则,血瘀及瘀毒内蕴是病毒性肝炎所致黄疸的病理特点,因此王老提出治疗时应注意活血化瘀及解毒,同时重视顾护脾胃之气。从病因病机、治法方药等方面阐述和总结名老中医王鸿士治疗病毒性肝炎所致黄疸的临床经验和学术思想,以便更好地传承与创新。  
      关键词:王鸿士;黄疸;病毒性肝炎;湿热;名医经验   
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      发布时间:2023-04-10
    • LI Jie,QI Tuan-jie,SUN Feng-xia
      Vol. 38, Issue 4, Pages: 313-314(2019) DOI: 10.16025/j.1674-1307.2019.04.003
      摘要:探究王鸿士"和肝法"治疗肝病的临床经验,利用和肝之法以致"肝和",从而达到治愈疾病的目的。王老对于和解法的认识独特,临床疏肝、理气、平亢、补衰多法运用,以致肝和。和肝之理、法、方、药相统一,为治疗肝病以及诸脏腑疾病的重要方法。  
      关键词:王鸿士;和解法;肝和;和肝;中医辨治   
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      发布时间:2023-04-10
    • YUAN Meng,SUN Feng-xia
      Vol. 38, Issue 4, Pages: 315-319(2019) DOI: 10.16025/j.1674-1307.2019.04.004
      摘要:王国玮师从已故中医肝病名老中医王鸿士,尤擅治疗各类慢性肝病,他认为"肝主疏泄"是慢性肝病生理病理基础,"湿邪留著"贯穿慢性肝病始终,重视脏腑关系,肝病日久必传脾、伤肾,治疗上善用理气药以疏肝郁,清热利湿或健脾祛湿贯穿肝病治疗始终,并配合和脾、固肾之法,遣方用药,谨守病机,屡获疗效。  
      关键词:慢性肝病;辨证论治;经验   
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      发布时间:2023-04-10
    • LI Guo-jing,FU Xu-yan,GAO Hui-juan,ZHANG Wei-hua,FENG Xing-zhong
      Vol. 38, Issue 4, Pages: 320-324(2019) DOI: 10.16025/j.1674-1307.2019.04.005
      摘要:Objective To observe the clinical efficacy of TCM comprehensive therapy with internal and external methods in treating diabetic peripheral neuropathy with Qi deficiency and blood stasis syndrome and its effect on serum IGF-1 and BNDF in order to explore its possible mechanism.Methods 72 cases of diabetic peripheral neuropathy with Qi deficiency and blood stasis syndrome were randomly divided into treatment group and control group with 36 cases in each group.At the same time of basic treatment of Western medicine,the treatment group was also treated with internal taking of Chinese herbal medicine combined with herbal fumigation and acupuncture,while the control group was treated with Chinese herbal medicine only all for three months.The total clinical effective rate,TCM syndrome score,Toronto clinical score, nerve conduction velocity and serum levels of IGF-1 and BNDF were observed before and after treatment.Results The total clinical effective rate was 91.1 % in the treatment group and 82.8 % in the control group.The curative effect of the treatment group was better than that of the control group(P<0.05).After treatment,the median nerve, sural nerve and tibial nerve conduction velocity in the treatment group were better than those in the control group(P<0.05),and the expression of serum IGF-1 and BNDF in the treatment group was better than that in the control group(P<0.05).There were no obvious adverse reactions,and liver and kidney function damage during the treatment.Conclusion TCM comprehensive therapy of internal and external treatment can significantly improve the clinical symptoms, neuropathy score and nerve conduction velocity of patients with diabetic peripheral neuropathy, and its mechanism may be related to the increase of serum IGF-1 and BNDF expression.  
      关键词:diabetic peripheral neuropathy;Qi deficiency and blood stasis syndrome;IGF-1;BNDF;TCM comprehensive therapy   
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      发布时间:2023-04-10
    • YANG Lan,CAO Yang,JIANG Xi,QU Jian-hua
      Vol. 38, Issue 4, Pages: 325-328(2019) DOI: 10.16025/j.1674-1307.2019.04.006
      摘要:To observe the effect of Qingre Chushi Decoction on improving facial skin characteristics of patients with damp-heat type of acne.Methods 65 patients with acne of damp-heat type were randomly selected from September 2016 to December 2017 in our hospital.They were treated with Qingre Chushi Decoction and 20 healthy people were taken as control group during the same period.The skin properties of acne patients and control group before and after treatment were quantitatively evaluated and analyzed by VISIA skin image analyzer.Results VISIA data showed that the absolute scores of red area,brown spot and purple substance of acne patients before and after treatment were significantly different from those of healthy people(P<0.01),and there was no significant difference between the absolute scores of pore and healthy people(P>0.05).The improvement of red area, brown spot and purple substance in patients with acne were observed at the 2 nd and 3 rd week after treatment with Chinese herbal medicine.Conclusion Qingre chushi Decoction can improve the red area,brown spot and purple substance of acne patients significantly.  
      关键词:Acne of damp-heat type;Qingre Chushi Decoction;Chinese herbal medicine;skin properties   
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      发布时间:2023-04-10
    • QU Zhi-cheng,CAO Ying,ZHANG Hong-sheng,XU Xiang-dong,PEI Xiao-lu,YAO Wei-hai
      Vol. 38, Issue 4, Pages: 328-331(2019) DOI: 10.16025/j.1674-1307.2019.04.007
      摘要:Objective To observe the clinical efficacy of Qingfei Huatan Decoction combined with moxifloxacin in the treatment of exterior cold and interior heat type of community-acquired pneumonia( CAP). Methods This study was an exploratory,prospective randomized controlled trial in which 70 patients with cold and interior heat type of community-acquired pneumonia were randomized into a trial group and a control group with 35 patients in each group. The control group was treated with intravenous infusion of moxifloxacin injection. The experimental group was given 200 m L of Qingfei Huatan Decoction on the basis of the control group 3 times a day. Both groups were treated for 7 days. The heat withdrawal time, cough VAS score before and after treatment,the blood routine,C-reactive protein,procalcitonin level,overall efficacy and safety evaluation were compared between the two groups. Results The antipyretic time of the experimental group( 1. 34 ± 0. 93 days) was significantly shorter than that of the control group( 2. 91 ± 1. 17 days)( P < 0. 05). The cough VAS scores of the two groups were significantly lowered than those before treatment( P < 0. 05). The experimental group was more obvious( P < 0. 05). The levels of WBC,CRP and PCT in both two groups were significantly lowered than those before treatment. The CRP in the experimental group was more significantly lowered than that in the control group( P < 0. 05). The total effective rate of the experimental group was 93. 94 %, and that of the control group was 84. 85 %( P < 0. 05). In the experimental group, local skin itching in the infusion area was seen in 2 patients of experimental group and, 1 in the control group, and insomnia 1 patient. Conclusion Qingfei Huatan Decoction combined with moxifloxacin can shorten the antipyretic time, relieve cough symptoms, and effectively inhibit inflammatory reactions in CAP patients with good clinical efficacy.  
      关键词:Qingfei Huatan Decoction;community-acquired pneumonia;exterior cold and interior heat syndrome;integrated Chinese and western medicine;clinical observation   
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      发布时间:2023-04-10
    • SUN Wu,GAO Jing-hua,YANG Ke-xin,YUAN Na,GAO Chun-yu,ZHU Li-guo
      Vol. 38, Issue 4, Pages: 332-335(2019) DOI: 10.16025/j.1674-1307.2019.04.008
      摘要:Objective To evaluate the clinical effects of modified Danggui Buxue Decoction in the treatment of postoperative posterior lumbar internal fixation.Methods According to digital table method,60 patients with lumbar spinal stenosis who underwent posterior decompression and internal fixation were randomly divided into treatment group and control group with 30 in each group.The treatment group was given conventional antibiotic therapy and modified Danggui Buxue Decoction after surgery.The control group was only given conventional antibiotic therapy after surgery.The clinical manifestations,drainage volume,temperature VAS score,Hgb and RBC were compared between two groups before and after the treatment.Results The drainage volume,max temperature,the VAS score,Hgb on day 1 and day 3 and RBC on day 1 were no statistically significant(P>0.05);The average fever days,Hgb on day 10,RBC on day 3 and day 10 were statistically significant(P<0.05).Conclusion For the postoperative posterior lumbar internal fixation,modified Danggui Buxue Decoction can surely improve anemia and shorten fever time.  
      关键词:Postoperative lumber vertebral;modified Danggui Buxue Decoction;case-control study;effect   
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      发布时间:2023-04-10
    • XU Cheng-yong,XU Ran,WANG Yu-guo,FENG Jian,DOU Yong-qi
      Vol. 38, Issue 4, Pages: 336-339(2019) DOI: 10.16025/j.1674-1307.2019.04.009
      摘要:To observe the effects of Astragalus membranaceus,Curcuma and its compatibility on the number of lung metastases and tumor epithelial-mesenchymal transition in Lewis tumor-bearing mice in order to study the role of epithelial-mesenchymal transition mechanism in inhibiting tumor metastasis, and analyze the application significance of Radix Astragali and Rhizoma Zedoariae compatibility.Methods Fifty mice with C57 Lewis tumors were randomly divided into model group,Cisplatin group,Huangqi single drug group,Ezhu single drug group and compatibility group.The mice were given drug intervention accordingly for 15 consecutive days after inoculation.The lungs were dissected for observation,and the number of nodules as big as more than 2 mm over the surface of the lungs was observed under a dissecting microscope; the tumor was removed from the underarms and the EnVision method was used to detect E-cad,MMP-2,and MMP-9 in the tumor tissues.Results The number of pulmonary metastatic nodules in the cisplatin group and the compatibility group was lower than that in the model group(P<0.05).The number of lung metastases in two monotherapy groups was less than that of the model group but there was no statistical difference;that in each Chinese medicine group was inferior to that in the cisplatin group(P<0.05),that in the compatibility group was less than that in the Huangqi and Ezhu group,but the difference did not show statistical significance.E-cad expression was higher in the cisplatin group and the compatibility group than in the model group(P<0.05).There was no significant difference between the two monotherapy groups and the model group;that in the Chinese medicine group was lower than that in the cisplatin group(P<0.05),that in the compatibility group was higher than that in the Ezhu group(P<0.05),compared with that in the Huangqi single drug group,there was not statistically significant.The expression of MMP-2 was not statistically significant in each group(P>0.05).The expression of MMP-9 was lower in the cisplatin group,the compatibility group,and the Ezhu group than that in the model group(P<0.05).There was no significant difference between the Huangqi group and the model group;that in each group was higher than that in the cisplatin group(P<0.05),that in the compatibility group was lower than that in the Huangqi single drug group,while similar to that in the Ezhu single drug group and there was no statistical difference between the compatibility group and the Huangqi monotherapy group(P<0.05).Conclusion The effect of Huangqi-Ezhu compatibility in inhibiting tumor metastasis is better than that of Huangqi and Ezhu used singly.The mechanism may be related to the increase of E-cad protein expression and the decrease of MMP-9 expression.The combination of Huangqi and Ezhu is superior to use them singly in enhancing E-cad expression,but is similar with Ezhu and better than Huangqi in decreasing the expression of MMP-9.  
      关键词:Huangqi;Ezhu;Epithelial-mesenchymal transition;E-cad;MMP-2;MMP-9   
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      发布时间:2023-04-10
    • HAN Lei,LI Yi,ZHAO Ping
      Vol. 38, Issue 4, Pages: 340-343(2019) DOI: 10.16025/j.1674-1307.2019.04.010
      摘要:Objective To observe radicular pain changes of rat model with acute nerve root irritation after spinal manipulative therapy and discuss the anti-inflammatory and biological mechanism of the manipulation.Methods 90 male SD rats were randomly divided into six groups with 18 rats in each group, including a blank group with no interference, a sham group with a sham surgery, a model group with an acute nerve root irritation set up by surgery but no other interference, a mobilization group with a simulating mobilization treatment on the L5-6, an etoricoxib group with etoricoxib lavaged.Common behaviors were observed and paw withdraw latency(PWL) induced by heat irritation was measured 1 day before surgery and on day 3,5,9,15,21 after surgery in 6 rats of each group.The L5 dorsal root ganglion(DRG) at the operative side were collected on day 9, 21 respectively after surgery for detecting the nitrite content in another 6 rats of each group.Results No obvious motor dysfunction was seen in all rats.The PWL in mobilization and etoricoxib group were significantly higher than that of the model group respectively(P<0.05); but no significant difference was found in PWL between these two groups(P>0.05).There was no significant difference in nitrite content of L5 DRG between mobilization and etoricoxib group(P>0.05), but there were significantly decreasing when compared with that of model group respectively(P<0.01).Conclusion Spinal mobilization can obviously alleviate inflammation irritation and pain sensitization with a similar effect caused by etoricoxib lavage.The therapeutic mechanism of spinal mobilization might be related with a reduction of nitrite content in acute nerve root irritation of rat model and improvement of absorption of inflammatory factors.  
      关键词:spinal mobilization;radicular pain;nociceptive pain;nitrite content   
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      发布时间:2023-04-10
    • GONG Xin,ZHUANG Yu-long,ZHENG Ling-qi
      Vol. 38, Issue 4, Pages: 344-346(2019) DOI: 10.16025/j.1674-1307.2019.04.011
      摘要:子宫内膜厚度是反映子宫内膜容受性的一个重要指标,薄型子宫内膜是生殖内分泌的疑难疾病,临床上常因此反复取消体外受精(IVF)周期或移植失败。迄今对其发病机制尚未明确,现代医学对该病的治疗方法有限,中医药的治疗得到了广大患者和西医同道的认可。目前中医缺少相关理论和辨证论治的思路和方案。根据国家名老中医金哲教授多年的临床经验,分别从病因、发病机制及治疗等方面对薄型子宫内膜的临证辨证思路进行总结。  
      关键词:不孕症;PCOS;卵巢功能减退;宫腔手术   
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      发布时间:2023-04-10
    • LIU Hong-xi
      Vol. 38, Issue 4, Pages: 347-351(2019) DOI: 10.16025/j.1674-1307.2019.04.012
      摘要:张允岭教授临证治疗失眠,辨证精准,追本溯源,四诊合参,善于抓住疾病的主要症状与兼夹症状,从而准确辨析失眠的病因病位病机,而根据其病机的夹杂不同,从本论治,标本兼顾。总结张允岭教授治疗失眠的临床经验,将其治疗失眠所对应的核心病机及相应的核心治法归类为:重镇安神张弛有度、透热除烦方药得当、行气活血病机明确、清热化湿辨证精准、祛痰开窍理法清晰、滋补肝肾标本兼治。同时通过分析张允岭教授以此为基准治疗失眠的处方思路,理法方药融汇其中,体现出失眠论治中的整体观念。通过分析归类总结张允岭教授治疗失眠的辨治要点和用药特点,以期为临床治疗失眠提供参考与借鉴。  
      关键词:张允岭;失眠;中医疗法;名家经验   
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    • LI LU
      Vol. 38, Issue 4, Pages: 351-354(2019) DOI: 10.16025/j.1674-1307.2019.04.013
      摘要:张珠凤主任善用中西医结合理论辨证论治脑积水。张主任认为脑积水致因极多,以实证多见;病机关键为血瘀水停阻络,因"瘀则生水",治疗强调采用通降大法,核心为"通络""利水""行瘀"。善于"辨病"与"辨证"相结合选方用药,重视利水、化瘀、通络药物的应用,主张先驱邪后扶正,首当祛除水瘀之邪,后当并以健脾益肾,善用虫类药物及"对药",并结合现代药理研究成果选方用药,从而提高临床疗效。  
      关键词:脑积水;张珠凤;辨证论治;老中医经验   
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    • DONG Qing,DONG Xue-yan,LI Zhong
      Vol. 38, Issue 4, Pages: 355-359(2019) DOI: 10.16025/j.1674-1307.2019.04.014
      摘要:乳腺癌是现代临床常见恶性肿瘤,发病率逐年升高。中医药对乳腺癌的认识已有千年历史。为了进一步拓展中医药治疗乳腺癌的理论与临床基础,采用古籍文献探索式方法,从乳腺癌的病名考究、病因病机、证候体征、辨证论治、调护转归等方面进行系统的文献整理,为后世医家提供临床诊疗思路。  
      关键词:乳腺癌;古籍;中医   
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    • Vol. 38, Issue 4, Pages: 360-362(2019) DOI: 10.16025/j.1674-1307.2019.04.015
      摘要:通过三伏贴防治小儿反复呼吸道感染研究讨论临床科研开始前、数据采集进行中以及研究后期数据分析过程中的质量控制方法和手段。回顾发现,加强临床科研的质量控制和数据管理需要加强临床研究方案的顶层设计;制定SOP、记录文件等加强文件化管理,分期分批培训研究者达到临床试验研究的同质性,采用多种手段减少失访率;数据分析要制定统计分析方案,并重视数据的清洗、转换和统计方法的选择。在实施方案中建立内部和外部质量控制体系,从而提高临床科研的质量。  
      关键词:质量控制;数据管理;临床科研;三伏贴;小儿;呼吸道感染   
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    • KANG Jia,JIANG Mei,ZHAO Su-rui
      Vol. 38, Issue 4, Pages: 363-365(2019) DOI: 10.16025/j.1674-1307.2019.04.016
      摘要:不孕症严重影响人类生殖健康,是目前全世界医学研究的热点及难点。20%~35%的不孕症为排卵障碍,而卵巢储备功能下降是引起排卵障碍的重要因素之一。该病发生的根源为肾虚,但心脾两虚是发病的重要因素,故临床治疗应以调和心脾、滋肾填精为主,方以加味甘麦大枣汤为主,随症加减,同时配合心理疏导、改变生活方式、药膳治疗、耳穴压豆、穴位贴敷及针灸等疗法,临床实践证明,中医药多途径治疗心脾两虚型卵巢储备功能下降不孕症疗效满意。  
      关键词:不孕症;卵巢储备功能下降;心脾两虚;中医药;多途径;药膳   
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    • SHAO Jian-zhu,LI Yue,MA Chen-huan
      Vol. 38, Issue 4, Pages: 366-368(2019) DOI: 10.16025/j.1674-1307.2019.04.017
      摘要:在"治未病"及"春夏养阳"思想的影响下,三伏贴疗法已在全国广泛流行。受仝小林教授其"脏腑风湿"理论启发,自拟以苓桂术甘汤为基础方的"三伏饮"疗法,即在自然界阳气最为旺盛的三伏天,通过内服通阳汤剂,以散发体内的伏寒邪气,要求患者分别于头伏、中伏、末伏分别服用数剂三伏饮汤药,进而达到预防和治疗"脏腑风湿病"或"冬病"的目的,此法可有效减轻"脏腑风湿病"发作的频率及程度。  
      关键词:春夏通阳;三伏饮;治未病;脏腑风湿   
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    • Vol. 38, Issue 4, Pages: 368-370(2019) DOI: 10.16025/j.1674-1307.2019.04.018
      摘要:糖尿病属于中医"消渴"范畴。下肢血管病变是糖尿病发展的常见严重并发症之一。阴津亏虚贯穿整个病变过程。阴虚为本,燥热为标。气为血之帅,血为气之母。阴伤气耗,气阴两伤,虚热内生,煎灼津液,炼液成痰;气虚血停,肢体脉络失养;水停气滞,气滞血瘀,脉络瘀阻,不通则痛;瘀久化热,热盛肉腐。从中医的整体观出发,糖尿病气血津液之间的变化,同样贯穿于糖尿病患者下肢缺血性疾病演变过程中。  
      关键词:糖尿病;下肢缺血;益气养阴;活血   
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    • LIU Tong-tong,RAO Xiang-rong,LI Shen
      Vol. 38, Issue 4, Pages: 371-373(2019) DOI: 10.16025/j.1674-1307.2019.04.019
      摘要:IgA肾病是公认的最常见的原发性肾小球疾病,IgA肾病的发病多由于外邪侵袭,因脏腑功能失调,正气无力抗邪,致使邪气盘踞不去,伏而内留,此与脏腑风湿病理论极为相似。通过从脏腑风湿理论阐述IgA肾病的发病规律,探讨以扶正气、透伏邪为基本原则,以三焦辨证与审因辨治相结合,以"急则治其标,缓则治其本"的指导原则论治IgA肾病的临床意义,以期为IgA肾病的中医治疗提供新的思路和治疗方法。并附以典型医案2则进行说明。  
      关键词:脏腑风湿理论;IgA肾病;中医药治疗   
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    • Vol. 38, Issue 4, Pages: 374-377(2019) DOI: 10.16025/j.1674-1307.2019.04.020
      摘要:食积发热是饮食停聚中焦,积而不化,郁而化热,内热不能被及时消导,外发成发热的一种发热类型。本病外因主要为饮食不节,食积停滞不化,伤及脾胃之气,气滞湿停而化热;内因多为脾胃虚弱,情志不遂,运化不及,饮食停滞不化,成为积滞,热与积滞相合,产生发热。在临床辩证施治过程中,应立足脾胃,抓住"食积为本,发热为标"的本质,灵活遣方用药,给邪以出路,方可消积去热。治疗重在消食化积,行滞退热。  
      关键词:食积;发热;中医药;辨证治疗   
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    • TIAN Tian,JIE Chuan-hong,REN Yan-ru
      Vol. 38, Issue 4, Pages: 377-379(2019) DOI: 10.16025/j.1674-1307.2019.04.021
      摘要:眼与肝密切相关,肝开窍于目,目为肝之外候。"肝足厥阴之脉……上连目系""肝气通于目"。眼病多因肝郁导致,情志不遂或病邪阻遏,使肝气郁滞,疏泄功能失常,郁久脉络瘀阻,血行不畅,从而影响视觉功能。根据"木郁达之"理论对眼病的临床治疗进行深入探讨,并提出肝郁致眼病不应拘泥于疏肝解郁,更应注重使气血调和,经脉运行通畅的治则,顺应肝木喜条达而恶抑郁的生理特性,故从补气健脾、滋阴养血、补益肝肾的治则展开论述。  
      关键词:木郁达之;肝郁;眼病   
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    • SHEN Yi-feng,ZHOU Qiao-yin,LI Shi-liang
      Vol. 38, Issue 4, Pages: 380-384(2019) DOI: 10.16025/j.1674-1307.2019.04.022
      摘要:目的通过检索和分析针刀相关文献以了解其当前的研究现状。方法以"needle knife;Small needle knife;acupotomy;Needle-knife therapy;Acupuncture-knife therapy;acupotomology"为检索词,在线检索SCI、Medline、Embase、Cochrane Library数据库,然后利用Endnote软件及人工对检索的文献进行分析。结果共检索出文献79篇,其中中文文献55篇,英文文献24篇;74篇为中国作者文献,3篇为韩国学者文献,2篇为美国学者文献。针刀大多译为"acupotomy"(54.41%)或"needle knife"(22.06%);补充和替代综合医学杂志及骨科、风湿等专科杂志都可接收针刀研究发表。韩国、美国已开展针刀或类针刀研究。针刀研究其核心著者主要来自北京中医药大学。针刀学科的整体研究水平还较低,文献量较少。结论针刀研究在国际上已初步具有影响力,其研究质量及其研究水平有待于进一步提高。  
      关键词:针刀;英文;文献分析   
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    • DING Jing-yong,REN Qin-you,ZHENG Jin
      Vol. 38, Issue 4, Pages: 384-387(2019) DOI: 10.16025/j.1674-1307.2019.04.023
      摘要:目的观察黄连温胆汤联合阿普唑仑治疗中度焦虑肿瘤患者失眠的疗效,探讨临床治疗肿瘤患者焦虑失眠的有效治法。方法将60例中度焦虑肿瘤(胆郁痰扰型)患者随机分为观察组和对照组各30例,2组均给予森田疗法心理治疗,其中对照组给予阿普唑仑口服;观察组在对照组基础上给予黄连温胆汤加减治疗,连续治疗14天,比较2组睡眠有效率,治疗前后中医证候量表、生活质量(KPS)、匹兹堡睡眠质量指数(PSQI)、焦虑生活量表(SAS)等评分,以及肿瘤坏死因子(TNF-α)、5-羟色胺(5-HT)、白介素-6(IL-6)的变化,监测2组不良反应。结果观察组缓解率96.7%;对照组为86.7%,组间比较差异有统计学意义(P<0.05)。2组治疗后KPS、中医证候量表评分、SAS、PSQI评分比较,差异均有统计学意义(P<0.05);2组治疗后TNF-α、IL-6、5-HT比较,差异亦有统计学意义(均P<0.05)。2组治疗前后均未出现不良反应。结论黄连温胆汤联合阿普唑仑治疗肿瘤患者失眠胆郁痰扰型确有良好疗效。  
      关键词:失眠;肿瘤焦虑;胆郁痰扰型;黄连温胆汤;阿普唑仑;中西医结合疗法   
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    • SHI Shuai,HU Yuan-hui,SONG Qing-qiao
      Vol. 38, Issue 4, Pages: 388-392(2019) DOI: 10.16025/j.1674-1307.2019.04.024
      摘要:目的系统评价丹田降脂丸治疗高脂血症的疗效和安全性。方法计算机检索Cochrane图书馆、PubMed、Embase、Medline、CNKI、CBM、VIP、万方数据库等数据库,纳入相关RCT,并进行评价,采用Revman 5.3软件分析数据。结果纳入8篇RCTs,共907例受试者。相比对照组,丹田降脂丸的血脂总疗效高于对照组(OR=5.30,95%CI[2.30,12.22],P<0.0001)。治疗后总胆固醇(TC)水平低于对照组(WMD=-0.84,95%CI[-1.28,-0.40],P<0.0002)。治疗后甘油三酯(TG)水平低于对照组(WMD=-0.45,95%CI[-0.70,-0.21],P<0.0003)治疗后高密度脂蛋白(HDL-C)水平高于对照组(WMD=0.29,95%CI[0.16,0.41],P<0.00001)。治疗后低密度脂蛋白(LDL-C)水平低于对照组(WMD=-0.52,95%CI[-0.85,-0.20],P<0.002)。各组不良反应发生率差异均无统计学意义(OR=0.74,95%CI[0.26,2.15],P=0.58)。结论丹田降脂丸治疗高脂血症疗效明显,对TC、TG、HDL-C、LDL-C的改善有效,不良反应发生率未见与其他药物有明显差异,推荐临床联合应用,并建议补充更多高质量的相关研究。  
      关键词:丹田降脂丸;高脂血症;系统评价   
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    • XU Guo-li,LU Yi-ping,GAO Jian-xin
      Vol. 38, Issue 4, Pages: 393-395(2019) DOI: 10.16025/j.1674-1307.2019.04.025
      摘要:目的观察参与型护理对胃癌合并糖尿病患者围手术期血糖控制情况的影响。方法将60例胃癌合并糖尿病围手术期患者随机分为2组,各30例。对照组接受以饮食管理为主的常规护理,观察组在此基础上接受参与型护理,包括饮食指导、中医特色护理、心理指导。观察2组患者术前及术后3个月空腹血糖(FBG)、餐后2 h血糖(2h BG)、糖化血红蛋白(HbA1c)、空腹胰岛素(FINS)水平,并通过稳态模型(HOMA-IR)评价胰岛素抵抗。结果术后3个月,观察组FBG、2hBG、HbA1c、HOMA-IR均低于对照组(P<0.05)。观察组血糖控制有效率为66.7%,高于对照组的20.0%(P<0.05)。结论参与型护理能有效控制胃癌合并糖尿病患者围手术期血糖,改善胰岛素抵抗。  
      关键词:参与型护理;中医特色护理;饮食管理;围手术期;胰岛素抵抗   
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    • LI Jia-yue,ZHANG Ying,HUANG Wei-jun
      Vol. 38, Issue 4, Pages: 396-399(2019) DOI: 10.16025/j.1674-1307.2019.04.026
      摘要:目的观察十八段锦对2型糖尿病胃肠实热型患者的护理效果。方法将符合入组标准的60例2型糖尿病患者随机分为对照组及观察组,每组30例,对照组在药物治疗不变的情况下给予基础护理措施,观察组在对照组的基础上加十八段锦练习,观察3个月,比较2组治疗前后糖化血红蛋白(HbA1c)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)、甘油三酯(TG)以及胃肠实热证候积分的变化。结果对照组干预后较干预前HbA1c、LDL-C、HDL-C、TG、证候积分分别下降0.18%、0.6 mmol/L、-0.45 mmol/L、0.20 mmol/L、8.19分;观察组分别下降-0.60%、-0.34 mmol/L、0.06 mmol/L、-0.41 mmol/L、-14.48分。治疗后与对照组比较,观察组血糖、血脂以及胃肠实热症状均有明显改善,其中HbA1c平均降低了0.6%(P<0.01);LDL-C下降0.34 mmol/L(P<0.01),HDL-C增加0.06 mmol/L(P<0.01),TG下降0.41 mmol/L(P<0.01);胃肠实热证候积分下降14.48分(P<0.01)。结论辨证练习十八段锦对改善患者的血糖、血脂以及临床症状均有较好的疗效。  
      关键词:2型糖尿病;胃肠实热证;十八段锦;辨证护理   
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