摘要:Objective To investigate the relationship between the clinical features and tongue manifestations of corona virus disease 2019(COVID-19)cases.Methods The symptoms,signs,laboratory examinations and imaging examinations of 40 COVID-19 patients together with tongue manifestations were analyzed.Results(1)Tongue manifestations: among 40 cases,all cases(100%)had red tongue,among which 19 cases(47.5%)had dark red tongue.There were 5 cases(12.5%)with little tongue coating,27 cases(67.5%)with white and sticky tongue coating,and 8 cases(20.0%)with yellow and sticky tongue coating.(2)Clinical manifestations: among the 40 patients,27 cases(67.5%)had fever,among them,18 cases(45.0%)had low fever(37.3-37.9℃),8 cases(20.0%)had moderate fever(38-38.9℃),and 1 cases(2.5%)had high fever(≥39℃).There were 25 cases of cough(62.5%),13 cases of fatigue(32.5%),6 cases of pharyngeal pain(15.0%),12 cases of muscle pain(30.0%),and 2 cases of diarrhea(5.0%).Those with red tongue with little tongue coating were milder,with only cough,pharyngeal pain,fatigue and so on,and pharyngeal pain were more common in those with thick and greasy tongue coating,the difference was statistically significant(P<0.05).The patients with white greasy and yellow greasy coating on the tongue were mainly characterized by cough and fever,among which the patients with white greasy coating on the tongue were mainly characterized by low fever,while the patients with yellow greasy coating on the tongue mostly had medium and high fever above 38℃,the difference was statistically significant(P<0.05).(3)Imaging findings: chest X-ray showed that among 40 cases,13 cases had bilateral pulmonary inflammation(32.5%),18 cases(45.0%)had unilateral pulmonary inflammation,including 7 cases(17.5%)of left pneumonia and 11 cases(27.5%)of right pulmonary inflammation,the remaining 9 cases(22.5%)showed no significant abnormality on chest X-ray examination.Most of the patients with red tongue with little tongue coating showed no abnormality in the imaging examination,and the chest X-ray indicated that the pulmonary inflammation was mostly those with thick and greasy coating on the tongue,among which bilateral sides of pneumonia was more common in those with red tongue with yellow greasy coating,the difference was statistically significant(P<0.05).(4)Laboratory examination: the white blood cell count of 40 cases was(5.17±1.55)×109/L,among which 3 cases were abnormally decreased(7.5%).The lymphocyte count was(1.39±0.75)×109/L,among which 8 cases(20.0%)were abnormally decreased.With the change of thickness and stickiness of tongue coating,the number of white blood cells increased gradually,while the number of lymphocytes decreased gradually,the difference was statistically significant(P<0.05).Conclusion COVID-19 patients with red tongue and little coating were more seen at the early stage with short course of disease(1-2 d),and milder symptoms,along with the progression(course of 3 d or more),the tongue coating become more in some patients,characterized by thick greasy coating,and the clinical manifestations are manifested by cough and fever,reflecting the progress of the infection,therefore,to sum up the therapeutic principle for the COVID-19 cases is heat clearing,lung dispersing and removing dampness without overuse too bitter cold herbal drugs.
摘要:Objective To explore the characteristics of TCM syndrome and pathogenesis by analyzing the clinical data of corona virus disease 2019 patients in the Beijing Youan Hospital,so as to provide further support for the clinical treatment.Methods There were 67 patients with corona virus disease 2019 hospitalized in the Beijing Youan Hospital until February 5,2020.And 27 patients of them who had complete information of tongue manifestations were selected to analyze the clinical manifestations and characteristics of TCM syndrome.Results Among 27 patients,fever was present in 22(81.0%),and there were 17(62.96%)cases presenting fever as the most common syndrome,then the second and third were lassitude in 11 cases(40.74%),general aching in 9 cases(33.33%).About the tongue manifestations,all 27 cases had thick sticky tongue coating,of them there were 3 cases(11.1%)of slightly red tongue,15 cases(55.6%)of red tongue,9 cases(33.3%)of dark red tongue.And all 27 cases had sticky tongue coating,including 17 cases(62.9%)of yellowish and greasy tongue coating.Among 27 cases,syndrome of epidemic toxin attacking lung was seen in 15 cases(55.56%),including 1 case of qi and yin deficiency,all of these had more pathogenic heat than pathogenic damp;syndrome of toxic damp accumulating in the lung was found in 12 cases(44.44%),all of these had more pathogenic damp than pathogenic heat.Conclusion The patients with the corona virus disease 2019 in Beijing are manifested as syndrome of accumulated dampness-heat.The red tongue and yellow fur imply obvious heat syndrome,and heat syndrome was more serious than dampness syndrome generally.The syndrome differentiation and treatment of TCM for the corona virus disease 2019 should follow the principle of "treatment in accordance with seasonal-local conditions and patient’s individuality."
摘要:Objective To observe TCM syndromes effect and safety of Shujin Jianyao Pill in the treatment of Lumbar Disc Herniation(LDH)(deficiency of liver and kidney syndrome and obstruction of wind damp and blood stasis syndrome).Methods According to the multi-centered,randomized and controlled clinical treatment regime,a total of 240 LDH patients who met the inclusion criteria were randomly divided into two groups,180 in the experimental group and 60 in the control group.There was no significant difference in the basic data between the two groups with comparability.The experimental group was given Shujin Jianyao Pill and Yaobitong Capsule Simulator orally,while the control group was given Shujin Jianyao Pill Simulator and Yaobitong Capsule orally.The treatment course of the two groups was 4 weeks.The total TCM syndrome score and single TCM symptom score on day 0,14 and 28 were observed,and the adverse reactions were recorded.Results There were significant differences in total TCM syndrome score between the two groups at baseline,on day 0 and day 28(P<0.01).There was significant difference in total TCM syndrome score between the two groups on day 28(P<0.05).There were significant differences between the two groups in total effective rate of total TCM syndromes and lumbago in single TCM syndromes score on day 28(P<0.05).There was no significant difference in the incidence of adverse events and serious adverse events between the two groups(P>0.05).Conclusion Shujin Jianyao Pill is effective on TCM syndromes in the treatment of LDH of deficiency of liver and kidney syndrome and obstruction of wind damp and blood stasis syndrome,especially in improving the score of total TCM syndrome score and lumbago with high safety.
摘要:Objective To discuss the characteristics of TCM patterns and syndromes of coal workers’ pneumoconiosis so as to enrich TCM theory for the treatment of this disease and provide the evidence for syndrome differentiation and treatment.Methods TCM syndromes of 208 patients with CWP were collected,investigated and statistically analyzed.Results The syndrome factors of workers’ pneumoconiosis included qi deficiency,heat(fire),exogenous wind,phlegm,blood stagnation,exogenous cold,deficiency of Yin,and endogenous damp.The locations of the illness are the lung,spleen and kidney.After differentiation of the patterns,TCM syndrome identified ten patterns: deficiency of lung qi,attack of lung by wind and heat,stagnation of blood,blockage of lung by phlegm heat,deficiency of spleen qi,attack of lung by wind and cold,blockage of lung by phlegm damp,deficiency of lung Yin,deficiency of Yin of kidney,and exterior cold and lung heat.Using cluster analysis of symptoms,seven kinds of patterns were identified: deficiency syndrome of lung qi,accumulation of phlegm heat in the lung,obstruction of lung by phlegm damp,attack of lung by wind and heat,stagnation of blood,deficiency of kidney Yin,and deficiency of spleen qi.When acute infection is complicated,the accompanied TCM syndrome types include blockage of the lung by phlegm heat,and blockage of the lung by wind and heat.Conclusion CWP is manifested by deficiency in the root and excess in the secondary condition.Deficiency of lung qi is the main root.Patients with CWP are liable to be infected by exogenous wind and cold.By means of cluster analysis,the main characteristics of TCM syndromes of CWP can be revealed to some extent.
摘要:Objective To observe the effects of Liqi Runchang Recipe on opioid-induced constipation.Methods 104 patients with constipation of Qi deficiency and Qi stagnation caused by using opioids were randomly divided into control group and treatment group with random number table method.The control group(n=52)was given oral Lactulose Oral Solution.The treatment group was given orally Liqi Runchang Recipe.Both two groups were treated for 2 weeks as a course of treatment.The score,TCM syndrome score before and after the treatment and the therapeutic effects of between the two groups were compared and the safety evaluated.Results There was no statistical difference between two groups before the treatment(P>0.05);the symptom score of two groups after the treatment were lowered(P<0.05),and the symptom score of treatment group was more lowered than that of the control group(P<0.05).The scores of TCM syndromes in both groups were decreased after treatment(P<0.05),and the scores in the treatment group were more significantly lowered than those in the control group(P<0.05).After the treatment,the findings of blood and stool routine,liver and kidney function,and ECG in both groups had no obvious changes.5 cases in the control group showed abdominal distension and nausea,which are probably the adverse reactions of Lactulose Oral Solution,so without management,these symptoms were alleviated.Any adverse reactions were found in the treatment group.Conclusion Liqi Runchang Recipe can effectively alleviate opioid-induced constipation,which has better effect than Lactulose Oral Solution.
摘要:ObjectiveTo explore the effect of "meridian flow" theory applied into Chinese medicine wax therapy on anxiety and depression in knee osteoarthritis patients.Methods A total of 66 patients with knee osteoarthritis were randomly divided into experimental group(n= 33)and control group(n=33).The experimental group was treated with time-selected Chinese medicine wax therapy based on meridian flow,while the control group was treated with conventional time traditional Chinese medicine wax therapy,both once a day,seven times as a course of treatment,and four courses of treatment together.VAS score,SAS score and SDS score were used to evaluate the pain of knee joints and psychological state in both two groups.Results The intra-group comparison showed that there were significant differences in VAS score,SAS score and SDS score between the two groups at 4 weeks of intervention and the difference was statistically significant(P<0.05).The comparison between the two groups showed that the scores of VAS,SAS and SDS in the experimental group were more lowered than those in the control group(P<0.05)at 4 weeks after intervention,and there was significant difference between the two groups(P<0.05).Conclusion The effect of meridian flow selective Chinese herbal wax therapy can effectively relieve pain and improve patients’ psychological state,which is better than that of conventional time Chinese herbal wax therapy.
摘要:目的探讨吴茱萸敷脐疗法配合穴位注射足三里治疗重症患者胃肠功能障碍的疗效。方法纳入符合诊断标准的入住ICU并伴有胃肠功能障碍的重症患者共80例,随机数字表法分为4组:常规组20例、单纯吴茱萸敷脐疗法组20例、单纯维生素B12穴位注射组20例、吴茱萸敷脐疗法+穴位注射组20例。通过比较4组患者治疗前和治疗7 d后急性生理及慢性健康(Acute Physiology and Chronic Health Evaluation,APACHEⅡ)评分、序贯性器官衰竭(Sequential Organ Failure Assessment,SOFA)评分、胃肠功能障碍评分、胃肠功能障碍改善疗效以及不良反应发生率,评价该中医外治法对重症患者胃肠功能障碍的效果。结果 4组患者治疗前一般情况(包括年龄、性别、APACHEⅡ评分、SOFA评分,胃肠功能障碍评分)比较,差异无统计学意义(均P>0.05),具有可比性。4组患者组内对比,治疗后APACHEⅡ评分、SOFA评分、胃肠功能障碍评分与治疗前相比有不同程度降低(P<0.05)。3个治疗组与常规组比较,治疗后APACHEⅡ评分、SOFA评分及胃肠功能障碍评分比较,皆有不同程度降低,其中吴茱萸敷脐疗法+穴位注射组下降最显著(P<0.05)。同时吴茱萸敷脐+穴位注射组与常规组比较,治疗后肠功能障碍改善疗效显著(P<0.05)。4组患者治疗前后血液、尿液、粪便三大常规以及肝、肾功能指标组间比较差异无统计学意义,未见明显不良反应。结论吴茱萸敷脐疗法配合穴位注射足三里可促进重症患者胃肠功能恢复,是一种安全、有效、简便的中医外治法。