最新刊期
期 3 ， 2020
- 摘要：炎症性肠病（inflammatory bowel disease, IBD）在我国的发病率及患病率均明显上升,其发病机制尚未完全明确,诊断和治疗均较困难。虽然5-氨基水杨酸类、糖皮质激素、免疫调节剂和生物制剂等为IBD治疗提供了许多行之有效的手段,但仍有大量患者病情得不到有效控制。中西医结合治疗可为IBD患者提供优化的治疗手段,在诱导深度缓解以及达标治疗中发挥重要作用。结合IBD流行病学与中西医结合治疗现状、治疗目标、临床定位、治疗原则、用药模式及临床应用等内容,对IBD中西医结合治疗策略进行阐述以供临床参考。关键词：炎症性肠病;中西医结合;溃疡性结肠炎;克罗恩病
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发布时间：2023-04-11 - 摘要：溃疡性结肠炎是一种慢性非特异性炎症性肠病,具有迁延难愈、反复发作的特点。笔者根据多年临床经验形成"整体辨证,局部辨病"诊疗模式,整体上采用分期辨证论治,活动期祛湿化瘀解毒以祛其邪,缓解期健脾补气温阳以固其本;局部以"痈疡"辨病论治,用中药青赤散灌肠,以敛疮生肌、燥湿止血。内服汤药,外用灌肠,"整体辨证"与"局部辨病"相结合治疗左半结肠型、轻中度溃疡性结肠炎,效果良好。关键词：溃疡性结肠炎;痈疡论治;整体辨证;局部辨病
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发布时间：2023-04-11 - 摘要：Objective To explore the therapeutic effect and mechanism of Huazhuo Jiedu Prescription in the treatment of ulcerative colitis（UC）.Methods 120 patients with UC were randomly divided into observation group and control group with 60 cases each.The observation group was treated with Huazhuo Jiedu Prescription one bag and twice a day,and the control group was treated with Mesalazide enteric coated tablets 1.0 g each time and 3 times a day.Continuous treatment lasted for 4 weeks as one course in both groups.The improvement of Geboes index,colonoscopy mucosal performance,quality of life score,Mayo activity index,serum inflammatory factors IL-8,IL-35,and coagulation index serum FIB levels before and after treatment were compared, and the recurrence was added up within one year after the treatment finished.Results After the treatment,the Geboes index,Mayo activity index,serum inflammatory factor IL-8 level,and blood coagulation index serum FIB levels in the observation group were lowered more than that before the treatment（P<0.05）.Particularly,Mayo activity index,serum inflammatory factor IL-8 level,and blood coagulation index serum FIB levels in the observation group were lower than that of the control group,quality of life scores,serum inflammatory factor IL-35 Level was higher than that of the control group after the treatment（P<0.05）.Compared with the control group,the improvement of erosion and ulcer in the treatment group was not significant（P>0.05）,and the improvement of intestinal mirror performance such as congested edema and granulomatous changes was better than that of the control group（P<0.05）.The relapse rate was 10.64% in the observation group,and 23.53% in the control group one year after treatment（P<0.05）.Conclusion Huazhuo Jiedu Prescription can improve the clinical symptoms of UC patients,repair the pathological damage of intestinal mucosa and reduce the recurrence rate.The mechanism may be related to the regulation of serum inflammatory factors IL-8,IL-35 and coagulation factor FIB.关键词：Ulcerative colitis;Huazhuo Jiedu;action mechanism
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发布时间：2023-04-11 - 摘要：Objective To explore the therapeutic effect and mechanism of Weichang’an Pill on dextran sodium sulfate（DSS）-induced ulcerative colitis in mice.Methods Sixty SPF C57 BL/6 mice were used.Except for normal control group of mice,the other mice were given 2.5% DSS aqueous solution with free consumption for 7 days to prepare ulcerative colitis models.After model evaluation,they were randomly divided into model group,Mesalazine group,Weichang’an Pill high-dose group,medium-dose group,low-dose group.The Weichang’an pill low,medium,and high dose groups were given 0.015,0.03,and 0.06 g/（kg·d）of Weichang’an pill suspension respectively by intragastric administration 0.5 mL,once a day; the mesalazine group was given 0.52 g/（kg·d）mesalazine suspension by intragastric administration of 0.5 mL once a day; the normal control group and model group were orally administered with equal volume of pure water,all for 10 consecutive days.The disease activity index（DAI）score and colon length of the mice in each group were compared,and the pathological and morphological changes of the colon tissue of the mice were observed with HE staining.The percentage of Treg,Th17,CD4+,and CD8+ lymphocyte in the spleen tissue was detected by flow cytometry.Serum cytokines TNF-α,IL-6,IL-8,IL-10 and CRP were detected by ELISA.Results During the drug intervention,the body weight of the mice in each group was increased day by day,and the symptoms such as diarrhea,hematochezia,and weight loss were alleviated day by day.Compared with the model group,the above symptoms could be alleviated more rapidly in the mesalazine group and Weichang’an Pill high-dose group.DAI scores of both two groups were reduced day by day（P<0.05）.After drug intervention,compared with the model group,the mice in the high-dose Weichang’an Pill group and mesalazine group had longer colons（P<0.05）,and the congestion of colon tissue,interstitial edema,and inflammatory cell infiltration were milder.Compared with the model group,the percentage of CD4+,CD8+,and Treg cells and serum IL-10 levels in the high-dose group of Weichang’an Pill and mesalazine were higher（P<0.05）; the percentage of Th17 cells and serum TNF-α,IL-6,IL-8,CRP level was lower（P<0.05）.Conclusion Weichang’an Pill can alleviate the intestinal mucosal damage induced by DSS in mice.The mechanism may be related to the restoration of Treg/Th17 immune balance and the regulation of related cytokines.关键词：Weichang’an Pill;Ulcerative colitis;dextran sodium sulfate;mice
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发布时间：2023-04-11 - 摘要：炎症性肠病（inflammatory bowel disease,IBD）是一种严重威胁人类健康的慢性非特异性肠道炎性疾病。近年来,其发病率及患病率逐渐增高,但仍存在诊疗体系复杂、药物治疗局限、缺乏长期管理等问题。中医药在维持缓解和预防复发方面优势凸显。从"天人合一"的整体观、多维度诊疗模式、中医复方与单方和内外治结合的确切疗效、改善体质、防止复发等方面,对中医药治疗IBD的特色与优势进行评述,以期进一步提高中医药治疗IBD的临床疗效。关键词：炎症性肠病;溃疡性结肠炎;克罗恩病;中医药;诊治现状;特色;优势
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发布时间：2023-04-11 - 摘要：炎症性肠病（IBD）是一组慢性非特异性肠道炎症性疾病,主要包括溃疡性结肠炎（UC）和克罗恩病（CD）,目前西医治疗存在并发症多、易复发的问题,中医药治疗展现其独特优势。从IBD的中医辨治、中医药疗效及治疗机制3个方面进行归纳及总结。IBD发病基础为正气不足、脾肾虚弱;中医药治疗分为解伏毒利湿,调气血,注重脾、肝、肾调理,同时可维持肠道菌群稳态,减轻炎症反应;中医药治疗IBD作用机制主要为维持以T细胞17（Th17）/调节性T细胞（Treg）为主的免疫微环境平衡和炎症介质的分泌调节。关键词：炎症性肠病;中医药治疗;疗效;机制
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发布时间：2023-04-11 - 摘要：为更好地指导北京市的中医药抗击新型冠状病毒肺炎疫情工作,北京市中医专家组紧密结合北京的地理气候特点和疫情救治经验,在第一、二版《北京市新型冠状病毒肺炎中医药防治方案》基础上修订了第三版并予以公布。在第三版中增加了中医病因病机部分,明确了疾病发展由疫毒袭肺、疫毒闭肺到内闭外脱的临床演变过程,治疗上注重采用宣肺透邪、清热利湿、解毒凉血等治法。方案包括了预防、治疗,以及儿童和成人的不同方案,有理论依据,实用性强。关键词：新型冠状病毒肺炎;中医药;方案;解读
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发布时间：2023-04-11 - 摘要：三因制宜是中医临床治疗疾病的法则。本次新型冠状病毒肺炎因南北地域不同、气候差别、人体体质各异,北方地区感受疫毒之邪病因病机与湖北武汉有所区别。北方地域气候、生活习性、饮食习惯易致体内郁热,病邪具有"郁、湿、热、毒"特点,易伤阴从热化。临床防治应扶正祛邪、三因制宜,才能取得良好的临床治疗效果。关键词：新型冠状病毒肺炎;三因制宜;中医药
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发布时间：2023-04-11 - 摘要：Objective To analyze the prescriptions for the prevention and treatment of novel coronavirus pneumonia（COVID-19）promulgated by national Chinese medicine masters and interpret their thoughts about syndrome differentiation and the laws of using drugs.Methods Search prescriptions for the prevention and treatment of COVID-19 promulgated by national Chinese medicine masters between January 1,2020 to February 12,2020.Results A total of 9 national medical masters released 22 prescriptions.8 masters including ZHOU Zhong-ying,SUN Guang-rong,TANG Zu-xuan,LI Dian-gui,JIN Shi-yuan,WANG Qi,XIONG Ji-bai,LIU Zu-yi made 9 preventive prescriptions,involving 32 kinds of herbs.These prescriptions were mainly used for replenishing qi,removing dampness,clearing heat and removing toxicity,supplemented by nourishing yin and clearing heat,dispersing wind and relieving the exterior syndrome,dispersing lung and resolving phlegm.TANG Zu-xuan,YANG Chun-bo,SUN Guang-rong and Li Dian-gui promulgated 10 treating prescriptions,involving 61 kinds of herbs.The prescriptions were based on the basic principle of "removing dampness,clearing heat and removing toxicity".Professor TANG gave treatment by differentiating of the pathogenic dampness combined with cold,heat and toxin respectively; Professor YANG made differentiation according to the transformation of dampness in the body; Professor LI focused on "dampness,heat and toxin"; Professor SUN emphasized "dispelling wind and clearing away heat".Master LI Dian-gui,ZHOU Zhong-ying and WANG Qi promulgated 3 prescriptions for perfume bags including 14 kinds of herbs,and everyone used Agastache to remove dampness by means of aromatics.Conclusion Many masters of Chinese Medicine actively participate in the prevention and treatment of COVID-19,their understandings about the etiology and pathogenesis of this disease was basically the same.No matter for treatment or for prevention,the prescriptions are mainly used to replenish qi,remove dampness,clear heat and remove toxicity.According to the statistics of drug use frequency,the most commonly used drugs are astragalus,agastache and honeysuckle.However,the specific syndrome differentiation and treatment are different.关键词：novel coronavirus pneumonia;national Chinese medicine masters;treatment;prevention;analysis of prescription
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发布时间：2023-04-11 - 摘要：观察新型冠状病毒肺炎病程中腹泻一症,结合临床辨证,提出此症出现原因及对总体辨证的影响。腹泻的发生在该病的初期及临床治疗过程中比例及原因不同,需对疾病初期腹泻及治疗过程中药物不良反应问题区别对待。新型冠状病毒肺炎是感受疫疠之气致病,无论是病情所致或药物不良反应,腹泻症状在临床上相对常见,属湿浊所致,治疗以祛湿为要。关键词：新型冠状病毒肺炎;腹泻症;中医辨析
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发布时间：2023-04-11 - 摘要：新型冠状病毒肺炎（COVID-19）患者除呼吸道症状以外,常伴有纳差腹胀、大便不调等消化道症状,舌苔往往厚腻,有湿邪侵犯中焦的特点。中医认为脾胃与肺关系密切,手太阴肺经起于中焦,下络大肠,还循胃口,与脾共司水液代谢。同时从国家及各地区发布的COVID-19中医诊疗方案中也可看出,针对脾胃的治疗贯穿始终,与《温疫论》中的观点不谋而合,因此在治肺的基础上应当重视脾胃的治疗。结合《温疫论》中相关论述及现有的报道和临床资料,参照《新型冠状病毒感染的肺炎诊疗方案（试行第五版）》疾病分期,探讨从脾胃角度防治COVID-19。关键词：新型冠状病毒肺炎;温疫论;脾胃;膜原
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发布时间：2023-04-11 - 摘要：王玉章教授在乳腺增生病的诊疗中,不仅对其病因病机的认知有独到之处,还提出"理、健、调"的治疗思路,反对过用攻伐之剂,其在理气、健脾、调冲任思路下研制中成药消癖糖浆临床使用至今。王老提倡外科重外治,使用消化膏外敷缓解乳腺疼痛、结节。其内外合治的理念对中医乳腺疾病治疗起到发展和推动作用。关键词：王玉章;乳腺增生;理气;健脾;调冲任;消癖糖浆;消化膏
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发布时间：2023-04-11 - 摘要：胡荫奇教授是全国名老中医,擅长治疗风湿病等内科疑难杂症。胡教授认为先天禀赋不足,饮食不节,导致脾肾功能失调,内生痰浊湿毒,湿浊是高尿酸血症（HUA）重要的病理因素。利湿化浊是HUA的治疗大法。自拟利湿降浊汤作为治疗HUA的专病专方。根据HUA患者不同体质、证候表现、病情轻重及疾病阶段,在利湿降浊汤的基础上,加减变化。在符合传统中药饮片性味归经、主治功效的前提下,结合现代药理循证遴选具有降尿酸药理作用的单味中药饮片。胡教授治疗HUA充分体现辨病与辨证相结合及循证选药。在药物治疗同时,重视强调HUA生活方式调整,男性慎饮食,女性避寒凉。关键词：胡荫奇;高尿酸血症;湿浊;名老中医经验
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发布时间：2023-04-11 - 摘要：原发性三叉神经痛属于难治性痛症,王麟鹏教授强调针刺治疗本病以远治、分季节论治为要,即选穴以四肢为主,并顺应四时阴阳消长为治疗思路。在春夏季节,配合阳经腧穴足三里、阳陵泉助阳升发;秋冬季节,配合阴经腧穴太溪、照海、三阴交滋阴养血,临床疗效显著。关键词：王麟鹏;原发性三叉神经痛;远治法;分季节法;针刺;名中医经验
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发布时间：2023-04-11 - 摘要：幼年特发性关节炎（juvenile idiopathic arthritis,JIA）是儿童最常见的结缔组织病之一,属中医学"痹病""小儿痹"范畴。由于儿童处于快速生长发育阶段,不同年龄段其身体功能亦有不同,故JIA多表现为不同的临床亚型。目前认为,先天禀赋不足、脾肾亏虚是JIA发病的内因,湿、瘀、毒三者相互作用则是其进一步发展变化的关键。湿、瘀、毒既可由内伤产生,也可由外感导致,同时湿浊和瘀血既是致病因素也是病理产物,而从湿浊到瘀血、从湿瘀成毒到湿瘀毒互结是JIA病情进展的两个质变。因此,正确认识湿、瘀、毒三者的来源及其在JIA发病中的相互关系十分重要,有助于提高JIA辨证论治的准确性,治疗上也应当重视祛湿、化瘀、解毒法的运用,同时还需考虑不同年龄段患儿的生理特性。关键词：幼年特发性关节炎;湿毒瘀;论治
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发布时间：2023-04-11 - 摘要：牡蛎泽泻散首出《伤寒论·辨阴阳易差后劳复病脉证并治》"大病差后,从腰以下有水气者,牡蛎泽泻散主之"。方中药物组成独具巧思,是仲景理法的重要组成部分,治疗上尤其注重通过软坚散结、利水消肿治疗慢性肾病出现的顽固性水肿。通过剖析牡蛎泽泻散的用药配伍,结合现代临床常见的慢性肾病对牡蛎泽泻散的临床疗效进行论述。关键词：经方;牡蛎泽泻散;伤寒论;慢性肾脏病;糖尿病肾病
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发布时间：2023-04-11 - 摘要：通过论述肝的生理功能、经脉分布以及医家从肝论治白疕经验、临证心得等,结合白疕的病机特点,探讨在整体辨证下,从肝入手针药并用调畅气血论治白疕的可行性,丰富了中医药治疗白疕的临证思路,为中医药从肝论治白疕提供了理论依据。关键词：白疕;银屑病;肝;中医辨证
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发布时间：2023-04-11 - 摘要：《本草图经》记载:"牛皮胶制作不甚精。"为求证原因,笔者以北魏《齐民要术》所载煮胶法为基础,分别用鲜牛皮与牛皮鞋制作牛皮胶。结果显示,鲜牛皮制作的牛皮胶出胶率高,胶呈琥珀色,色泽明亮,拍之即碎,断面有玻璃茬,无腥秽气味;而用牛皮鞋制作的牛皮胶出胶率低,胶呈黑褐色,色泽晦暗,不易干燥,拍之难碎,断面无玻璃茬,有轻度腥秽气味。由于北宋的皮革业发展水平远远高于北魏时期,后者鞋履等旧皮多为未经过鞣制的生皮,前者则为经过鞣制的熟皮。因此,《本草图经》记载的"牛皮胶制作不甚精"真实原因可能是煮制过程中使用了充分鞣制过的熟牛皮。关键词：牛皮胶;阿胶;炮制;本草图经;熟牛皮
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发布时间：2023-04-11 - 摘要：血虚证是临床常见证候,通过对中医古籍中血虚证相关论述的整理,从病因病机、临床表现及舌脉象、治则治法三个方面对血虚证的源流进行考证。总结历代医家对血虚证病因病机及证候的认识,同时对血虚证的治则治法进行综述并深入剖析,规范其理法方药体系,明确其临床应用指征,以期拓宽血虚证临床治疗思路,并为血虚证的理论与临床研究提供借鉴。关键词：血虚证;源流;病因病机;临床表现;舌脉;治则
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发布时间：2023-04-11 - 摘要：目的探讨孔伯华先生辨治中风病的思路与用药规律。方法利用古今医案云平台,梳理《孔伯华医案存真》及《孔伯华》两书中"中风"一章的所有医案,对体征、症状、证型、治法、方药进行统计分析。结果医案中涉及的舌象有腻、厚、白、黄等15种;脉象有弦、数、滑等24种;症状有发热、便秘、言语謇塞等40种;中医证型有痰证、肝热动风等20种;治法有豁痰、达络、润导等36种,药物有石膏、旋覆花、代赭石等154种。结论孔伯华先生以痰壅热盛、外邪中窍、气机逆乱为中风病主要病机;祛痰平逆、通腑泄热、疏风达络为主要治法;用药切合病机,并能随机应变。关键词：孔伯华;中风;辨证论治;用药
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发布时间：2023-04-11 - 摘要：目的探索社区原发性高血压患者中医证型分布情况及其相关因素。方法对来源于北京市3个社区的原发性高血压患者,根据中医证素特征进行辨证分型,观察中医证型分布情况,并进一步分析证型分布与年龄、性别、饮酒、合并心肌梗死的关系。结果共纳入符合条件的原发性高血压患者1 069例,中医证型分布为痰湿壅盛证446例（41.7%）、阴虚阳亢证237例（22.2%）、肝火亢盛证197例（18.4%）、阴阳两虚证189例（17.7%）。不同性别、年龄及是否饮酒、合并心肌梗死的原发性高血压患者中医证型分布存在差异（P<0.05）。结论社区原发性高血压患者的中医证型以痰湿壅盛证为主,性别、年龄、饮酒及合并疾病等因素对其中医证型的分布存在一定影响。关键词：高血压;中医证型;分布规律;社区
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发布时间：2023-04-11 - 摘要：目的观察头部腧穴针刺治疗卒中后中枢性疼痛（CPSP）的临床效果。方法选择2016年1月—2018年12月北京中西医结合医院针灸科和脑病科收治的CPSP患者138例,随机分为针刺组和药物组,剔除脱落患者,最终针刺组和药物组分别为67例和62例。针刺组给予头部腧穴针刺,每周5次,药物组给予每天口服阿米替林,25 mg/次,2次/日,均治疗4周。对比2组疗效及治疗前后疼痛视觉模拟评分（VAS）、简明McGill疼痛问卷评分、SF-36生活质量评分。结果针刺组总有效率高于药物组（P<0.05）。治疗后2组VAS评分、疼痛评级指数（PRI）感觉项、PRI情感项、PRI总分、现在疼痛状况（PPI）均较治疗前降低（P<0.05）,且针刺组低于药物组（P<0.05）。2组SF-36生活质量评分均较治疗前升高,针刺组效果优于对照组（P<0.05）。结论头部腧穴针刺能够有效缓解CPSP患者的症状,提高其生活质量。关键词：脑卒中;中枢性疼痛;头部腧穴;针刺
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发布时间：2023-04-11 - 摘要：目的观察自拟健脾祛浊通络汤治疗慢性肛周湿疹脾虚痰瘀阻滞证的临床疗效,并探讨其可能的作用机制。方法选择2017年1月—2018年11月就诊的慢性肛周湿疹患者80例,按随机数字表法分为对照组与治疗组各40例。2组均采用复方亚甲蓝注射液肛周局部点状封闭治疗,对照组给予口服盐酸左西替利嗪片5 mg/d,肛周局部外用丁酸氢化可的松乳膏;治疗组给予自拟健脾祛浊通络汤内服与肛周熏洗治疗。2组均治疗4周。对比2组治疗前后瘙痒程度、皮损形态、皮损面积评分及皮肤病生活质量指数（DLQI）评分;检测2组治疗前后血清白细胞介素-4（IL-4）、白细胞介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）及总IgE;对比2组疗效。结果 2组治疗后瘙痒程度、皮损形态、皮损面积及DLQI评分均较治疗前降低（P<0.05）,且治疗组低于对照组（P<0.05）。2组治疗后血清IL-4、IL-6、TNF-α及总IgE水平均较治疗前降低（P<0.05）,且治疗组低于对照组（P<0.05）。治疗组总有效率高于对照组（P<0.05）。结论自拟健脾祛浊通络汤能够减轻慢性肛周湿疹患者的瘙痒程度,改善皮损状态,减小皮损面积,提高生活质量及临床疗效,其作用机制可能与降低机体炎症因子水平、抑制变态反应有关。关键词：健脾祛浊通络汤;慢性肛周湿疹;疗效;作用机制
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发布时间：2023-04-11 - 摘要：目的观察手法结合揿针治疗膝骨关节炎（knee osteoarthritis,KOA）的临床疗效。方法选择北京市丰盛中医骨伤专科医院骨科2016年9月—2017年1月收治的KOA患者70例（70膝）,按随机数字表法分为试验组和对照组各35例。试验组脱落1例,对照组脱落3例,最终试验组入组34例,对照组32例。对照组给予基础治疗+手法治疗,试验组给予基础治疗+手法治疗+揿针治疗。采用日本骨科协会（JOA）评分,对比2组治疗前、治疗后及随访4周膝关节症状疗效。结果试验组无患者对揿针出现不耐受和过敏反应。试验组治疗后、随访4周JOA评分与治疗前比较差异有统计学意义（P<0.05）;试验组治疗后、随访4周JOA评分与对照组比较差异有统计学意义（P<0.05）。结论手法结合揿针治疗KOA效果优于单纯应用手法治疗。关键词：膝骨关节炎;手法;揿针;针刺治疗
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发布时间：2023-04-11 - 摘要：目的观察疏肝健脾颗粒剂（Shugan Jianpi Granule,SGJP）治疗乳腺癌癌因性疲乏（breast cancer related fatigue,BCRF）的临床疗效。方法采用单臂临床试验方法,纳入40例BCRF肝郁脾虚证患者,服用SGJP 8周,观察治疗前及治疗后4、8、12周Piper疲乏自评量表（PFS）、体能状况（ECOG）评分、中医证候量表、综合性医院焦虑抑郁量表（HAD）评分、匹茨堡睡眠质量指数量表（PSQI）评分及血尿便常规、生化等安全性指标。结果 38例患者完成全部随访,2例发生脱落。PFS、中医证候量表、HAD焦虑量表评分均在试验第4、8、12周显著下降,ECOG评分、HAD抑郁量表均在试验第8、12周显著下降,PSQI评分在治疗第12周显著下降,差异均有统计学意义（P<0.05）。在整个随访过程中,所有患者在治疗后未出现明显血常规、尿便常规及生化指标异常。结论 SGJP可以减轻乳腺癌患者的疲乏,增强体力,改善焦虑抑郁及睡眠质量,值得临床借鉴。关键词：乳腺癌;癌因性疲乏;疏肝健脾
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发布时间：2023-04-11 - 摘要：目的基于中医传承辅助平台软件分析运用化浊解毒理论治疗糖尿病中药处方的用药规律。方法在中国知网（CNKI）、万方和维普数据库检索运用化浊解毒理论治疗糖尿病中药处方,检索词为"化浊解毒"和"糖尿病",检索时间为收录起始年至2018年11月23日。采用关联规则、复杂系统熵聚类等数据挖掘方法,分析处方中药物的使用频次和关联规则,挖掘核心药物组成和新处方。结果共检出226条符合标准的处方,确定黄连、佩兰为高频使用药物;频次24次以上的药物组合19对,其中前3位分别为黄连+佩兰（64次）,佩兰+苍术（33次）,玄参+佩兰（32次）;挖掘出14个核心组合和7首新处方。结论应用化浊解毒理论治疗糖尿病时,药物以清热药、化湿药为主,活血药、淡渗利湿药、补气药、理气药为辅,其中以黄连、佩兰为主,治法主要以化浊解毒为主,淡渗利湿和活血化瘀为辅,兼顾调达气机。关键词：化浊解毒;糖尿病;用药规律
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发布时间：2023-04-11 - 摘要：目的分析北京中医药大学东方医院君药或臣药是毒性饮片的口服中成药临床使用情况,为临床合理用药提供参考。方法抽取本院2015—2017年度门诊中成药电子处方,对其中使用君药或臣药是毒性饮片中成药的患者情况进行统计分析。结果本院2015—2017年开具的主药为毒性饮片的中成药有45种,占全部中成药品种数的11.6%,占含毒性饮片中成药品种数的44.6%。其中女性、老年患者使用此类中成药的比例较大,用药科室以骨科为主。门诊使用率较高的中成药为麝香保心丸、小儿感冒宁糖浆、小金丸等。结论医院应对使用主药为毒性饮片中成药"数量多""种类广""风险高"的科室进行重点监测,尤其应关注老年患者等重点人群的合理用药情况,以期提高以毒性饮片为主药的口服中成药的用药安全性。关键词：毒性饮片;中成药;合理用药;用药安全
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发布时间：2023-04-11
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