Objective To explore the application of QOL scale in the clinical research of pediatric eczema and the problems. Methods The literatures about application of QOL scale in the clinical research of pediatric eczema in China and abroad were reviewed and the present status were analyzed. Results The utilization of QOL in China was still in learning period,and meanwhile the content of selfdesigned scales only involved infants’ dermatitis quality of life index （IDQo L）. The research of QOL scale in other countries was at the exploratory stage. Its reliability and validity need further to be checked and tested. But the open access to the database and website can make it possible for further study. Conclusion The specific QOL scale for pediatric eczema should combine with the advantages of other scales based on the existing scale,and take the reliability and validity into account to make it reasonable,effective and practical.