Objective To explore the evaluation value of modified early warning score（MEWS）and acute physiology and chronic health evaluation score（APACHEⅡ）score on prognosis of sepsis patients with different syndrome types in ICU.Methods 187 sepsis patients in ICU of Guang′anmen Hospital of China Academy of Chinese Medical Sciences from January 2016 to December 2017 were scored in TCM syndrome types, MEWS and APACHE Ⅱ.The scores of two different types of syndromes were compared, as well as the mortality of different syndrome types, the two ROC curves drawn, the correlation and the AUC calculated,prognostic evaluation value of scores in two types evaluated;the correlation of scores of types.Results The mortality and two kinds of scores from low to high were the deficiency syndrome,excessive syndrome, syndrome of intermingled deficiency and excess, and the deficiency syndrome and the other two syndromes were statistically different（P<0.05）.The two scores of syndrome of intermingled deficiency and excess could effectively predict the death condition, and the correlation was significantly correlated with the Spearman test（P<0.01）;the mortality rates before and after the best truncation point of different syndrome type two scores were compared.The difference was statistically significant（P< 0.05）.Conclusion Two scores can evaluate the condition and evaluate the prognosis in the evidence and deficiency syndrome.