Objective To analyze the prescriptions for the prevention and treatment of novel coronavirus pneumonia（COVID-19）promulgated by national Chinese medicine masters and interpret their thoughts about syndrome differentiation and the laws of using drugs.Methods Search prescriptions for the prevention and treatment of COVID-19 promulgated by national Chinese medicine masters between January 1,2020 to February 12,2020.Results A total of 9 national medical masters released 22 prescriptions.8 masters including ZHOU Zhong-ying,SUN Guang-rong,TANG Zu-xuan,LI Dian-gui,JIN Shi-yuan,WANG Qi,XIONG Ji-bai,LIU Zu-yi made 9 preventive prescriptions,involving 32 kinds of herbs.These prescriptions were mainly used for replenishing qi,removing dampness,clearing heat and removing toxicity,supplemented by nourishing yin and clearing heat,dispersing wind and relieving the exterior syndrome,dispersing lung and resolving phlegm.TANG Zu-xuan,YANG Chun-bo,SUN Guang-rong and Li Dian-gui promulgated 10 treating prescriptions,involving 61 kinds of herbs.The prescriptions were based on the basic principle of "removing dampness,clearing heat and removing toxicity".Professor TANG gave treatment by differentiating of the pathogenic dampness combined with cold,heat and toxin respectively; Professor YANG made differentiation according to the transformation of dampness in the body; Professor LI focused on "dampness,heat and toxin"; Professor SUN emphasized "dispelling wind and clearing away heat".Master LI Dian-gui,ZHOU Zhong-ying and WANG Qi promulgated 3 prescriptions for perfume bags including 14 kinds of herbs,and everyone used Agastache to remove dampness by means of aromatics.Conclusion Many masters of Chinese Medicine actively participate in the prevention and treatment of COVID-19,their understandings about the etiology and pathogenesis of this disease was basically the same.No matter for treatment or for prevention,the prescriptions are mainly used to replenish qi,remove dampness,clear heat and remove toxicity.According to the statistics of drug use frequency,the most commonly used drugs are astragalus,agastache and honeysuckle.However,the specific syndrome differentiation and treatment are different.