1.东南大学附属中大医院中西医结合男科,南京 210009
孙大林,男,36岁,博士研究生。研究方向:中西医结合治疗男科病。
金保方,E-mail: hexiking@126.com
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孙大林,金保方.微循环理论在男性不育症中西医诊治中的应用价值探讨[J].北京中医药,2022,41(12):1346-1350.
SUN Da-lin,JIN Bao-fang.Application value of microcirculation theory in the diagnosis and treatment of male infertility with traditional Chinese and western medicine[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(12):1346-1350.
孙大林,金保方.微循环理论在男性不育症中西医诊治中的应用价值探讨[J].北京中医药,2022,41(12):1346-1350. DOI: 10.16025/j.1674-1307.2022.12.005.
SUN Da-lin,JIN Bao-fang.Application value of microcirculation theory in the diagnosis and treatment of male infertility with traditional Chinese and western medicine[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(12):1346-1350. DOI: 10.16025/j.1674-1307.2022.12.005.
微循环是人体循环的基础,可以调控生精内环境,与精子生成、成熟和排泄紧密相关,对维持生殖功能至关重要。中医学的气、血、经络理论与微循环密切相关,中医学对微循环障碍的病机概括为血瘀证。微循环障碍是男性不育的重要因素,是多种病因导致的共同病理结果。临床使用中、西药改善微循环,促进生精环境的营养代谢,在治疗男性不育中发挥重要价值。
Microcirculation, the basis of human circulation, can regulate the internal environment of spermatogenesis, is closely related to spermatogenesis, maturation and excretion, and plays an important role in maintaining reproductive function. The theory of qi and blood and the theory of meridians and collaterals in traditional Chinese medicine are closely related to microcirculation. Blood stasis syndrome is the summary of pathogenesis of microcirculation disorder in traditional Chinese medicine. Microcirculation disturbance is an important factor in male infertility, and is a common pathological result caused by a variety of etiologies. Clinical use of traditional Chinese medicine and/or western medicine to improve microcirculation and promote the nutrient metabolism of spermatogenic environment plays an important role in the treatment of male infertility.
生殖微循环男性不育症生精内环境血瘀证精血同源
Reproductive microcirculationmale infertilityinternal environment of spermatogenesisblood stasis syndromeessence and blood sharing the same source of
金亦涵,金保方,孙大林,等.养精胶囊在男性生殖微循环中的作用及机制研究进展[J].中国男科学杂志,2021,35(5):90-92.
谷亚龙,张新东,金保方.睾丸微循环概述[J].中国男科学杂志,2015,29(2):61-65.
SCALA G, DE GIROLAMO P, CORONA M, et al. Microvasculature of the buffalo epididymis [J]. Anat Rec, 2002,266(1):58-68.
王丹丹,孙大林,金保方.胰激肽原酶在男性生殖领域的研究进展[J].中华男科学杂志,2021,27(5):445-449.
常成成,魏聪,吴以岭.脉络学说“孙络-微血管”概念及其临床指导意义[J].中医杂志,2016,57(1):7-11.
李林森,田金洲,蔡艺灵,等.血瘀证生物学基础研究进展[J].山东中医杂志,2010,29(12):863-865.
田牛,李玉珍,刘育英.血瘀证的微循环研究[J].中国中西医结合杂志,2001,21(4):248-251.
顾磊,金保方,张新东.睾丸微循环结构及功能调控的研究进展[J].微循环学杂志,2014,24(3):65-67.
姜辉,戴继灿,李宏军.胰激肽原酶在男性不育中的临床应用专家共识(2018版)[J].中国男科学杂志,2018,32(3):59-63.
王佳宇,周党侠.16例克氏综合征患者的临床及病理分析[J].内蒙古医学杂志,2021,53(7):855-856,859,898.
农君仁. AZF基因微缺失无精子症患者睾丸病理观察[D].南宁:广西医科大学,2008:14-16.
曾国华. 先天性梗阻性无精子症患者CFTR基因突变及其睾丸超微结构的研究和ICSI治疗的临床观察[D].广州:中山医科大学,2000:18-20.
闫振龙. 牦牛睾丸促性腺激素受体和性激素受体增龄性变化与免疫调控研究[D].兰州:甘肃农业大学,2014:2-9.
UNEMOTO T, MATSUSHITA M, TAMURA K, et al. Role of BK channels in testosterone-induced relaxation of the aorta in spontaneously hypertensive rats [J]. Biol Pharm Bull.2007,30(8):1477-1480.
TSIMARIS P,DELIGEOROGLOU E,ATHANASOPOULOS N,et al. The effect of hormone therapy on biochemical and ultrasound parameters associated with atherosclerosis in 46, XY DSD individuals with female phenotype[J]. Gynecol Endocrinol,2014,30(10): 721-725.
GONZALVO V, NAVALÓN P, LLORIS JM. Effect of LHRH agonists on testicular microcirculation with Doppler laser flowmetry [J]. Actas Urol Esp,1996,20(9): 772-782.
DHOLE B, GUPTA S, KUMAR A. Triiodothyronine stimulates steroid and VEGF production in murine Leydig cells via cAMP-PKA pathway [J]. Andrologia, 2021,53(3):e13972.
ALSAIKHAN B, ALRABEEAH K, DELOUYA G, et al. Epidemiology of varicocele [J]. Asian J Androl,2016,18(2):179-181.
COZZOLINO DJ, LIPSHULTZ LI. Varicocele as a progressive lesion: positive effect of varicocele repair [J]. Hum Reprod Update,2001,7(1):55-58.
SALAMA N, BERGH A, DAMBER JE. Microvascular testicular blood flow as evaluated by laser Doppler flowmetry after the surgical induction of varicocele [J]. Arch Androl,2001,46(3):197-204.
HVIID A, RUBIN S, MÜHLEMANN K. Mumps[J]. Lancet,2008,371(9616):932-944.
胡志祥,邹丹阳,廖春洁,等.梅毒螺旋体对新西兰兔睾丸的病理损伤及其对精子产生的影响[J].中国男科学杂志,2019,33(4):15-20.
郝东方,张峰. 成年男性睾丸微石症的生精功能分析[J]. 中国性科学,2020,29(1):24-26.
ZAFAR MI, YU J, LI H. Implications of RNA Viruses in the male reproductive tract: an outlook on SARS-CoV-2 [J]. Front Microbiol,2021,12:783963.
苏艺峰,陈其华.立足血瘀病机浅析以经方论治精索静脉曲张[J].环球中医药,2022,15(1):128-130.
邢益涛,黄卫,彭玉平,等.308例男性不育症患者舌脉的流行病学研究[J].中国男科学杂志,2022,36(5):68-72.
李宏军,洪锴,李铮,等.男性不育诊疗指南[J].中华男科学杂志,2022,28(1):66-76.
LEE SH, LEE S. Genetic association study of a single nucleotide polymorphism of kallikrein-related peptidase 2 with male infertility[J]. Clin Exp Reprod Med,2011,38(1):6-9.
FANG Y, ZHAO L, YAN F, et al. Escin improves sperm quality in male patients with varicocele-associated infertility [J]. Phytomedicine,2010,17(3-4):192-196.
MATTEO M, CICINELLI E, BALDINI D, et al. Influence of human menopausal gonadotrophin treatment on testicular blood flow and on seminal plasma nitric oxide levels in infertile males [J]. Int J Androl,2006,29(4): 441-445.
金保方.生殖微循环学[M].北京:中国中医药出版社,2022:295-344.
金保方,黄宇烽,夏欣一,等. 养精胶囊联合锌硒宝对不育患者精子DNA完整性的影响[J]. 中国男科学杂志,2006,20(12):45-49.
张华俊. 养精胶囊治疗DAZ基因缺失所致无精子症的临床价值[D].南京:南京中医药大学,2010:23.
张靖,孙大林.补肾活血汤对特发性男性不育症精子质量和VEGF的影响[J].中国男科学杂志,2020,34(1):52-55.
董伟航,金保方,孙大林,等.补肾活血方通过VEGF/VEGFR2相关通路促进生精障碍模型小鼠睾丸微循环的研究[J].中国男科学杂志,2018,32(2):30-35.
JIN B, SUN D, DONG W, et al. Yangjing Capsule can improve the function of the testicular angiogenesis through activating VEGFA/eNOS signaling pathway[J]. Evid Based Complement Alternat Med,2020:1957267.
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