Objective,2,To explore the clinical efficacy of the method of removing obstruction，clearing away toxin and removing blood stasis in the treatment of severe mycoplasma pneumonia with the syndrome of toxic heat obstructing the lung.,Methods,2,A total of 200 patients with severe mycoplasma pneumonia who were hospitalized in Beijing Children's Hospital from January 2019 to December 2021 were enrolled and divided into treatment group and control group of 100 cases in each one according to random number table method. The control group was treated with conventional western medicine for 10-14 days as total courses，and the treatment group was treated with traditional Chinese medicine by stages on the basis of western medicine. The curative effect，time of fever，cough， wheezing and lung rales disappearing，D-dimer，lactate dehydrogenase（LDH），lesion absorption，incidence of atelectasis， obstructive bronchitis and gastrointestinal dysfunction before and after treatment were compared between the two groups.,Results,2,After one week of treatment， the clinical effective rate in the treatment group was higher than that in the control group（,P,=0.029）.After 4 weeks of treatment， the clinical cure rate and effective rate of the treatment group were higher than those of the control group， but the difference was not statistically significant（,P,>,0.05）；during the 12-week follow-up， the clinical cure rate of the treatment group was higher than that of the control group（,P,=0.009）. Compared with the control group， the disappearance time of fever，cough and pulmonary rales in the treatment group was significantly shortened（,P,<,0.05）. There was no significant difference in disappearance time of wheezing between the two groups（,P,>,0.05）. After one week of treatment， the level of D-dimer and LDH was significantly decreased（,P,<,0.05），and the level of D- dimer in the treatment group was lower than that in the control group（,P,<,0.05），and there was no significant difference in LDH level between the two groups（,P,>,0.05）. The complete absorption rate of lesions in the treatment group was higher than that in the control group（,P,<,0.05）.The incidence of atelectasis，obliterative bronchitis， and gastrointestinal dysfunction was significantly reduced（,P,<,0.05）.,Conclusion,2,The treatment of severe mycoplasma pneumonia with integrated traditional Chinese and western medicine has obvious advantages in promoting the relief of clinical symptoms with better effect than western medicine only.