1.首都医科大学附属北京中医医院耳鼻咽喉科,北京 100010
王雅琴,女,35岁,大学本科,主治医师。研究方向:耳鼻咽喉科疾病的中西医结合治疗。
王俊阁,E-mail:wjgent@163.com
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王雅琴,赵竞一,艾建伟,等.腺样体伴扁桃体肥大患儿切除术后应用芍药四物解肌汤的临床疗效观察[J].北京中医药,2023,42(10):1135-1138.
WANG Ya-qin,ZHAO Jing-yi,AI Jian-wei,et al.Clinical observation on application of Shaoyao Siwu Jieji Decoction in children with blood deficiency type after tonsillectomy with adenoidectomy[J]. Beijing Journal of Traditional Chinese Medicine,2023,42(10):1135-1138.
王雅琴,赵竞一,艾建伟,等.腺样体伴扁桃体肥大患儿切除术后应用芍药四物解肌汤的临床疗效观察[J].北京中医药,2023,42(10):1135-1138. DOI: 10.16025/j.1674-1307.2023.10.021.
WANG Ya-qin,ZHAO Jing-yi,AI Jian-wei,et al.Clinical observation on application of Shaoyao Siwu Jieji Decoction in children with blood deficiency type after tonsillectomy with adenoidectomy[J]. Beijing Journal of Traditional Chinese Medicine,2023,42(10):1135-1138. DOI: 10.16025/j.1674-1307.2023.10.021.
目的,2,观察血虚型腺样体伴扁桃体肥大患儿切除术术后应用芍药四物解肌汤的临床效果。,方法,2,选择2020年7月1日—2022年6月30日首都医科大学附属北京中医医院耳鼻咽喉科病房接受扁桃体伴腺样体切除术的、辨证属血虚证的患儿120例,采用随机数表法按照1∶1比例分为2组,观察组60例,术后给予口服芍药四物解肌汤口服,连续服药1周;对照组60例,术后给予头孢呋辛钠静脉滴注,每8 h 1次,连续用药1周。观察2组术后发热情况及手术前后实验室指标变化、面部表情疼痛量表(FPS-R)评分、术区伪膜情况及中医证候评分。,结果,2,观察组中度以上发热率低于对照组(,P,<,0.05),发热时间短于对照组(,P,<,0.05)。术后第1、第3天,2组白细胞(WBC)、C反应蛋白(CRP)水平与术前比较,差异均有统计学意义(,P,<,0.05),2组间差异亦有统计学意义(,P,<,0.05)。2组术前及术后4 h的FPS-R评分差异无统计学意义(,P>,0.05);术后第3日,观察组FPS-R评分低于对照组(,P,<,0.05)。观察组伪膜脱落时间较对照组早(,P,<,0.05)。术后,2组各项中医证候评分均较术前降低(,P,<,0.05);2组面色眼睑及唇甲色白评分比较,差异无统计学意义(,P>,0.05);观察组头晕、乏力、大便不通评分均低于对照组,差异有统计学意义(,P,<,0.05)。,结论,2,应用芍药四物解肌汤可减轻或避免发生扁桃体伴腺样体切除术术后不良反应,利于促进血虚型患儿术后康复。
Objective,2,To explore the application of Shaoyao Siwu Jieji Decoction after tonsillectomy with adenoidectomy in children with tonsil and adenoid hypertrophy of blood deficiency.,Methods,2,A total of 120 children with blood deficiency syndrome who underwent tonsillectomy with adenoidectomy were randomly divided into Chinese medicine treatment group and western medicine control group according to 1∶1 ratio. The Chinese medicine treatment group was given orally Shaoyao Siwu Jieji Decoction after operation, and the western medicine control group was given intravenous injection of cefuroxime sodium after operation once every 8 hours for one week.The postoperative fever, changes of laboratory indexes before and after operation, facial expression pain scale (FPS-R) score, pseudomembrane in operation area and TCM syndrome score were observed and compared between the two groups.,Results,2,The moderate fever rate of the treatment group was lower than that of the control group(,P,<,0.05),The duration of fever days was shorter than that of the control group(,P,<,0.05). After treatment, the white blood cell count (WBC) and C-reactive protein concentration in the treatment group were lower than those in the control group on the first day and third day after operation and the differences were statistically significant (P,<,0.05), and the differences between the two groups were also statistically significant(,P,<,0.05).After operation, the FPS-R scores of both groups were higher than those before operation (P,<,0.05), and the observation group was lower than the control group(,P,<,0.05). The time of pseudomembrane shedding in the control group was later than that in the treatment group.After operation, the scores of TCM syndromes in the two groups were lower than those before operation(,P,<,0.05).There was no significant difference between the two groups(,P,>,0.05).The scores of dizziness, fatigue and stool obstruction syndrome in the treatment group were lower than those in the control group, and the difference was statistically significant(,P,<,0.05). There was a statistically significant difference in total score of TCM syndrome score between the two groups (,P,<,0.05).,Conclusion,2,The application of Shaoyao Siwu Jieji Decoction after tonsillectomy and adenoidectomy in children with blood deficiency can reduce or avoid the adverse reactions after tonsillectomy and promote the postoperative rehabilitation of children.
芍药四物解肌汤小儿扁桃体伴腺样体肥大扁桃体伴腺样体切除术血虚证
Shaoyao Siwu Jieji Decoctiontonsils accompanied with adenoid hypertrophy in childrentonsillectomy with adenoidectomyblood deficiency syndrome
孙书臣,马彦,乔静,等.儿童腺样体肥大引发睡眠呼吸障碍的中医诊疗专家共识[J].世界睡眠医学杂志,2014,1(6):316-320,313
周仲瑛.中医内科学[M].北京:中国中医药出版社,2007:45.
BIERI D, REEVE RA, CHAMPION GD, et al. The faces pain scale for the self-assessment of the severity of pain experienced by children: development,initial validation.and preliminary investigation for ratio scale properties[J]. Pain, 1990,41(2):139-150.
曹隆和,戴志坚,朱传赛,等.等离子扁桃体包膜内切除术治疗儿童睡眠呼吸暂停综合征的效果观察[J].浙江临床医学,2023,25(1):93-95.
周成勇,孙宝春,王丰,等.低温等离子辅助下儿童腺样体和扁桃体手术临床疗效观察[J].临床耳鼻咽喉头颈外科杂志,2016,30(11):863-866.
倪鑫.中国儿童阻塞性睡眠呼吸暂停诊断与治疗指南(2020)[J].中国循证医学杂志,2020,20(8):883-900.
董宜祥,罗国隆.扁桃体切除术后出血及发热问题综合报告(附110例临床分析)[J].贵阳中医学院学报,1982(1):31-32.
高娟,张亚梅.儿童阻塞性睡眠呼吸暂停低通气综合征诊断方法[J].中国耳鼻咽喉头颈外科,2008,15(1):19-21.
张昌秦.血虚证自评量表的初步研制及考评[D].福州:福建中医药大学,2016.
金超,孙璇君,刘婷婷.白芍总苷与芍药苷抗衰老作用及其机制研究进展[J].医药导报,2022,41(3):355-360.
许晶,王婧,吴洁雅,等.基于黄芩汤YIV906(PHY906)思考中医药抗肿瘤现代化研究策略[J].北京中医药,2022,41(12):1393-1397.
朱青青,李雪玲,严佳怡,等.葛根素对高糖环境下H2O2诱导人足细胞氧化应激及线粒体损伤的保护机制[J].北京中医药,2022,41(2):125-131.
孙慧娟,朱鏐娈,王宪波,等.升麻的研究进展[J].中国中医基础医学杂志,2021,27(5):837-840.
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