1.南京中医药大学第一临床医学院,南京 210023
2.连云港市中医院骨伤科,连云港 222004
3.连云港市中医院检验科,连云港 222004
宋洁菲,女,23岁,大学本科。研究方向:中医肺系疾病的临床研究。
周迎光,E-mail:47494535@qq.com
纸质出版日期:2024-01-25,
收稿日期:2023-04-07,
扫 描 看 全 文
宋洁菲,周迎光,胡妍,等.基于血栓弹力图观察活血利水法对髋部骨折术后凝血状态的影响[J].北京中医药,2024,43(1):44-47.
SONG Jie-fei,ZHOU Ying-guang,HU Yan,et al.Observation on the effect of method for promoting blood circulation and diuresis on coagulation state after hip fracture surgery based on thromboelastogram[J]. Beijing Journal of Traditional Chinese Medicine,2024,43(01):44-47.
宋洁菲,周迎光,胡妍,等.基于血栓弹力图观察活血利水法对髋部骨折术后凝血状态的影响[J].北京中医药,2024,43(1):44-47. DOI: 10.16025/j.1674-1307.2024.01.009.
SONG Jie-fei,ZHOU Ying-guang,HU Yan,et al.Observation on the effect of method for promoting blood circulation and diuresis on coagulation state after hip fracture surgery based on thromboelastogram[J]. Beijing Journal of Traditional Chinese Medicine,2024,43(01):44-47. DOI: 10.16025/j.1674-1307.2024.01.009.
目的
2
通过血栓弹力图(TEG)观察早期应用活血利水法治疗对髋部骨折术后凝血状态的影响。
方法
2
选取股骨颈骨折或股骨粗隆间骨折患者60例,按照随机数字表法分为治疗组和对照组,各30例。所有股骨颈骨折患者行人工髋关节置换术,股骨粗隆间骨折患者行股骨近端髓内钉(PFNA)内固定术,术后给予常规治疗。治疗组在此基础上,术后次日起口服活血利水类中药汤剂,7 d为1个疗程。分别于术后第1、第7日测定患者大腿围及TEG指标。
结果
2
术后第1日,2组大腿围、TEG指标及凝血状态比较,差异无统计学意义(
P
>
0.05);术后第7日,治疗组CI值、MA值、α角低于对照组,K时间高于对照组,大腿围小于对照组,血液高凝患者人数少于对照组,差异均有统计学意义(
P<
0.05)。
结论
2
在髋部骨折术后早期应用活血利水法治疗能够有效减轻术后肿胀,改善患者TEG指标,减少血液高凝状态的发生,加速术后康复。
Objective
2
To observe the clinical effect of the method for promoting blood circulation and diuresis in early stage after hip fracture operation based on thrombelastogram (TEG).
Methods
2
60 patients with femoral neck fracture or intertrochanteric fracture were randomly divided into treatment group and control group with 30 cases each. The patients with intertrochanteric fracture were treated with Proximal Femoral Nail Antirotation (PFNA) ,those with femoral neck fracture were treated with artificial hip replacement. All patients were given routine treatment after operation. The treatment group was given Taohong Siwu Decoction and Wuling Powder on the next day after surgery for 1 weeks in addition to routine treatment.On the 1st and 7th day after surgery, fracture clinical syndrome score (FCSS) and TEG were determined.
Results
2
On the 1st day after operation,there was no significant difference in thigh circumference, TEG index and coagulation state between the two groups (
P
>
0.05) . On the 7th day after operation, CI, MA, α in the treatment group were lower than those in the control group, K time was longer than that of the control group
the thigh circumference of the treatment group was smaller than that of the control group
the number of hypercoagulable patients was less than that of the control group. The difference was statistically significant (
P
<
0.05).
Conclusion
2
Early application of Taohong Siwu Decoction after hip fracture operation can effectively reduce postoperative swelling
improve the TEG Index and reduce the occurrence of hypercoagulable state so as to accelerate the early recovery of patients after operation.
活血利水法桃红四物汤五苓散股骨粗隆间骨折股骨颈骨折血栓弹力图
Method for promoting blood circulation and diuresisTaohong Siwu DecoctionWuling Powderintertrochanteric fracturefemoral neck fracturethromboelastogram
沈淑劲,卢建华,储小兵,等. 活血利水法对全膝关节置换术后血栓弹力图及凝血功能的影响[J]. 中华中医药杂志, 2022, 37(2): 1209-1212.
陈威. 血栓弹力图在评估深静脉血栓形成高危因素的应用价值探讨[D]. 贵阳:贵阳医学院, 2014.
王亦璁,姜保国. 骨与关节损伤[M].5版. 北京: 人民卫生出版社, 2012: 1160.
郑筱萸. 中药新药临床研究指导原则(试行)[M]. 北京: 中国医药科技出版社, 2002: 340-342.
沈萍萍,夏圣. 不同疾病中血栓弹力图与凝血4项对凝血功能的一致性分析[J]. 中国现代医学杂志, 2019, 29(9): 79-84.
卫勇,李军,张勇,等. 髋部骨折患者术前下肢深静脉血栓发生率及高危因素[J]. 中国组织工程研究, 2020, 24(27): 4338-4342.
崔晓燕,徐其洋. 利伐沙班与低分子肝素在骨折置换术后下肢深静脉血栓中的预防效果及安全性[J]. 血管与腔内血管外科杂志, 2022, 8(6): 718-722.
陈双,周迎光. 基于数据挖掘分析中药内服治疗骨折术后肿胀的用药规律[J]. 实用临床医药杂志, 2021, 25(12): 13-17.
韦婷婷,黄雪霞,孟立锋,等. 五苓散加减治疗糖尿病肾病研究概况[J]. 中医学报, 2022, 37(2): 311-315.
王佐梅,肖洪彬,李雪莹,等. 桃红四物汤的药理作用研究进展[J]. 现代中医药, 2021, 41(2): 22-28.
聂欣,成颜芬,王琳,等. 桃红四物汤化学成分、药理作用、临床应用的研究进展及质量标志物的预测分析[J]. 中国实验方剂学杂志, 2020, 26(4): 226-234.
周迎光,陈建斌,陈双,等. 桃红四物汤联合五苓散加减在老年股骨粗隆间骨折患者围术期的应用[J]. 实用临床医药杂志, 2021, 25(20): 85-88.
SPAHND-R, BOUILLON B, CERNY V, et al. Management of bleeding and coagulopathy following major trauma: an updated European guideline[J]. Crit Care, 2013, 17(2): R76.
许寻,杨建业,秦磊磊,等. 血栓弹力图预测髋膝关节置换术后血液高凝状态的价值分析[J]. 骨科, 2020, 11(3): 199-205.
0
浏览量
2
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构