针灸在急性肺损伤中的保护作用研究进展

王书鹏; 李涛; 王慧; 吴筱箐; 马军宇; 吴依娜; 段军

doi:10.16025/j.1674-1307.2025.05.027

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针灸在急性肺损伤中的保护作用研究进展

文献综述 | 更新时间：2025-07-07

- 针灸在急性肺损伤中的保护作用研究进展
- Review of the protective role of acupuncture and moxibustion in acute lung injury
- 北京中医药 2025年44卷第5期页码：671-674
- 作者机构：
  
  北京市中日友好医院重症医学科，北京 100029
- 作者简介：
  
  王书鹏，男，44岁，硕士，副主任医师。研究方向：重症医学，急性呼吸窘迫综合征的中西医结合诊疗。
  段军，E-mail： web_document@163.com
- 基金信息：
  
  2022年度北京市重大疫情防治重点专科项目(2022-ZX-007)
- DOI：10.16025/j.1674-1307.2025.05.027
  中图分类号：
- 收稿日期：2024-05-28，
  
  纸质出版日期：2025-05-25
- 稿件说明：
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王书鹏，李涛，王慧，等.针灸在急性肺损伤中的保护作用研究进展［J］.北京中医药，2025，44（5）：671-674.

WANG Shupeng,LI Tao,WANG Hui,et al.Review of the protective role of acupuncture and moxibustion in acute lung injury[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(05):671-674.
王书鹏，李涛，王慧，等.针灸在急性肺损伤中的保护作用研究进展［J］.北京中医药，2025，44（5）：671-674. DOI： 10.16025/j.1674-1307.2025.05.027.

WANG Shupeng,LI Tao,WANG Hui,et al.Review of the protective role of acupuncture and moxibustion in acute lung injury[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(05):671-674. DOI： 10.16025/j.1674-1307.2025.05.027.

摘要

急性肺损伤是由各种原因所致的弥漫性肺部炎症，针灸在多种慢性呼吸道疾病防治中有明显的抗炎特性，其作用机制涉及免疫调节的各方面，可通过神经介导的免疫调节机制发挥肺保护作用，该过程涉及多种信号传递系统，包括胆碱能抗炎通路、Toll样受体4/活化B细胞的核因子κB通路、核苷酸结合寡聚化结构域样受体通路、p38丝裂原活化蛋白激酶通路、肾素-血管紧张素系统、Janus激酶1/转导和转录激活因子3通路等。鉴于其多靶点、多途径的抗炎和肺保护作用，针灸疗法在急性肺损伤的预防和早期治疗方面均有很好的应用前景。

Abstract

Acute lung injury （ALI） arises from a variety of causes and is marked by diffuse pulmonary inflammation， with immune response dysregulation as its primary underlying mechanism. The inflammatory process in ALI is complex and multifaceted， rendering immunotherapy targeting a single pathway less effective. In contrast， acupuncture therapy has demonstrated notable anti-inflammatory effects in the prevention and management of various chronic respiratory diseases， with a broad mechanism of action that encompasses multiple facets of immune regulation. This raises the question of whether acupuncture could also exert a lung-protective effect in patients with ALI， making it a topic worthy of exploration. This review synthesizes findings from recent animal experiments and clinical studies to evaluate the lung-protective potential of acupuncture therapy， elucidate its possible mechanisms， and discuss its prospects and challenges for clinical application.

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references

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